P3.23. Association of oral cancer susceptibility and DNA double strand break gene Ku70 single nucleotide polymorphisms

2009 ◽  
Vol 3 (1) ◽  
pp. 208
Author(s):  
T.C. Wen ◽  
T.H. Chang ◽  
W.C. Hsing ◽  
W.H. Chung ◽  
C.C. Hsiang ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Cancer Susceptibility ◽  
Strand Break ◽  
Double Strand Break ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Dna Double Strand Break

Association between DNA double strand break gene Ku80 polymorphisms and oral cancer susceptibility

Oral Oncology ◽  
2009 ◽  
Vol 45 (9) ◽  
pp. 789-793 ◽  
Author(s):  
Chia-Fang Hsu ◽  
Hsien-Chang Tseng ◽  
Chang-Fang Chiu ◽  
Shiu-Yun Liang ◽  
Chia-Wen Tsai ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Susceptibility ◽  
Strand Break ◽  
Double Strand Break ◽  
Dna Double Strand Break

scholarly journals RAD51 and XRCC3 Polymorphisms Are Associated with Increased Risk of Prostate Cancer

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Maria Nowacka-Zawisza ◽  
Agata Raszkiewicz ◽  
Tomasz Kwasiborski ◽  
Ewa Forma ◽  
Magdalena Bryś ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Strand Break ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Dna Double Strand Break ◽  
Repair Efficiency ◽  
Increased Risk ◽  
Pcr Rflp ◽  
Repair Genes

Genetic polymorphisms in DNA repair genes may affect DNA repair efficiency and may contribute to the risk of developing cancer. The aim of our study was to investigate single nucleotide polymorphisms (SNPs) in RAD51 (rs2619679, rs2928140, and rs5030789) and XRCC3 (rs1799796) involved in DNA double-strand break repair and their relationship to prostate cancer. The study group included 99 men diagnosed with prostate cancer and 205 cancer-free controls. SNP genotyping was performed using the PCR-RFLP method. A significant association was detected between RAD51 rs5030789 polymorphism and XRCC3 rs1799796 polymorphism and an increased risk of prostate cancer. Our results indicate that RAD51 and XRCC3 polymorphism may contribute to prostate cancer.

scholarly journals The Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a and miR-499 with Breast Cancer Susceptibility

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e70656 ◽  
Author(s):  
Ping-Yu Wang ◽  
Zong-Hua Gao ◽  
Zhong-Hua Jiang ◽  
Xin-Xin Li ◽  
Bao-Fa Jiang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Cancer Susceptibility ◽  
Breast Cancer Susceptibility ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide
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