P3.22. Evaluation of the expression of cytokeratins in exfoliative cytology of oral mucosa from smoking patients

2009 ◽  
Vol 3 (1) ◽  
pp. 208
Author(s):  
C. Lima ◽  
S. Leite ◽  
Y. Carvalho ◽  
L. Cabral ◽  
J. Almeida
Keyword(s):  
Oral Mucosa ◽  
Exfoliative Cytology

Exfoliative Cytology of Oral Mucosa in Kidney Transplant Patients: A Cytomorphometric Study

2011 ◽  
Vol 43 (3) ◽  
pp. 871-875 ◽  
Author(s):  
M. Keles ◽  
U. Tozoglu ◽  
D. Unal ◽  
F. Caglayan ◽  
A. Uyanik ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Oral Mucosa ◽  
Exfoliative Cytology ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Mechanical Ventilation and Cytopathological Changes in the Oral Mucosa

2017 ◽  
Vol 26 (4) ◽  
pp. 297-302 ◽  
Author(s):  
Ana Carolina Machado Landgraf ◽  
Angélica Reinheimer ◽  
Júlio Cezar Merlin ◽  
Soraya de Azambuja Berti Couto ◽  
Paulo Henrique Couto Souza
Keyword(s):  
Mechanical Ventilation ◽  
Intensive Care ◽  
Oral Mucosa ◽  
Oral Care ◽  
The Other ◽  
Control Group ◽  
Oral Epithelium ◽  
Exfoliative Cytology ◽  
Intensive Care Patients ◽  
Glass Slides

BackgroundThe oral mucosa is an important defense barrier to penetration of microorganisms. Thus, changes in the oral epithelium might indicate risk for infection in intensive care patients receiving mechanical ventilation.ObjectiveTo evaluate the oral mucosa of intensive care patients who did or did not receive mechanical ventilation by using liquid-base exfoliative cytology.MethodsThe sample consisted of 3 groups: 27 patients admitted to intensive care during a 7- to 14-day period who received mechanical ventilation, 29 patients admitted during the same period who did not receive mechanical ventilation, and 27 healthy patients who had no lesions in the mouth. For all 3 groups, samples were collected from the buccal mucosa by using cytology brushes. Smears were applied to glass slides before Papanicolaou staining and were codified for blind analyses by a cytopathologist. Kruskal-Wallis and Dunn tests were used to analyze the results.ResultsPatients receiving mechanical ventilation had higher prevalence and intensity of karyomegaly, perinuclear halos, cell keratinization, deep cells, and leukocyte infiltrates than did patients in the other 2 groups (P < .05). No significant differences were observed between the control group and the group who did not receive mechanical ventilation.ConclusionsLiquid-base exfoliative cytology can be used to detect preclinical alterations in the oral mucosa. Patients treated with mechanical ventilation are vulnerable to infections, and oral care may be valuable in their prognosis.

scholarly journals Erratum to “Evaluation of oral mucosa epithelium in type II diabetic patients by an exfoliative cytology method”

2009 ◽  
Vol 51 (3) ◽  
pp. 493
Author(s):  
Hassan Hosseinpour Jajarm ◽  
Nooshin Mohtasham ◽  
Maryam Moshaverinia ◽  
Afsaneh Rangiani
Keyword(s):  
Oral Mucosa ◽  
Diabetic Patients ◽  
Exfoliative Cytology ◽  
Type Ii ◽  
Mucosa Epithelium

scholarly journals Cytological Changes in Normal Oral Mucosa of Individuals with Tobacco Habits: A Cytomorphometric Study

2017 ◽  
Vol 18 (8) ◽  
pp. 722-727
Author(s):  
Pavan G Kulkarni ◽  
Pavan Palakurthy ◽  
Rateesh K Nandan ◽  
T Madhusudan Rao ◽  
D Shyam P Reddy ◽  
...  
Keyword(s):  
Head And Neck ◽  
Oral Mucosa ◽  
Head And Neck Cancers ◽  
Exfoliative Cytology ◽  
Control Groups ◽  
Normal Oral Mucosa ◽  
Cellular Changes ◽  
Group I ◽  
Cytological Changes ◽  
Tobacco Chewing

ABSTRACT Introduction Oral cancer is one of the six most common cancers in the world, and globally more than 50% of head and neck cancers occur in Asia, remarkably in India. Overall, 200,000 cases of head and neck cancers occur each year in India, among which 80,000 are oral cancers. Epidemiological and clinical studies suggest a causative role of tobacco use in the evolution of oral potentially malignant and malignant disorders. Aims and objectives The aim of the study is to evaluate independently and compare the cytological effects of smoking, tobacco chewing, and smoking in conjunction with tobacco chewing on oral mucosa by cytomorphometric analysis. Materials and methods The study included a total of 120 individuals subdivided into four groups, each group with 30 individuals. Group I was tobacco smokers, group II tobacco chewers, and group III both tobacco smokers and chewers. Group IV comprised 30 individuals without tobacco habit. Smears were prepared from buccal mucosa of both the study and control groups using a cytobrush and stained using Papanicolaou staining. The cells were quantified using image analysis software. Results The results of the study showed alterations in the nuclear and cellular parameters in the study groups when compared with control groups and were statistically significant (p < 0.05). Conclusion The present study explains the significance of early identification of cellular changes in individuals with tobacco habits who require early intercession even without any visible oral mucosal changes. The study emphasizes that exfoliative cytology and cytomorphometry aid as a valuable tool to evaluate the effect of tobacco on oral mucosa. Clinical significance Simple noninvasive techniques like exfoliative cytology can be employed as a chairside technique and in mass screening programs for identification of cellular changes in oral mucosa of individuals with tobacco habits. Thereby, it can be used as an early diagnostic tool for identification of potentially cancerous and cancerous lesions. How to cite this article Palakurthy P, Kulkarni PG, Nandan RK, Rao TM, Reddy DSP, Muddana K. Cytological Changes in Normal Oral Mucosa of Individuals with Tobacco Habits: A Cytomorphometric Study. J Contemp Dent Pract 2017; 18(8):722-727.

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