P2.30. Postoperative complications after primary curative surgery for advanced oral and oropharyngeal carcinoma

2009 ◽  
Vol 3 (1) ◽  
pp. 171
Author(s):  
J. Gonçalves-Filho ◽  
E. Pontes ◽  
I.M.G. Agra ◽  
L.P. Kowalski
Keyword(s):  
Postoperative Complications ◽  
Oropharyngeal Carcinoma ◽  
Curative Surgery ◽  
Oral And Oropharyngeal Carcinoma

Major surgery of oral and oropharyngeal carcinoma

1992 ◽  
Vol 106 (2) ◽  
pp. 127-129 ◽  
Author(s):  
T. Alun Jones ◽  
I. Gallow ◽  
S. L. Sellars ◽  
D. H. Kranold ◽  
G. R. Sealy
Keyword(s):  
Overall Survival ◽  
Postoperative Complications ◽  
Salvage Surgery ◽  
Squamous Carcinoma ◽  
Major Surgery ◽  
Oropharyngeal Carcinoma ◽  
Primary Procedure ◽  
Primary Radiotherapy ◽  
Time Of Presentation ◽  
Oral And Oropharyngeal Carcinoma

AbstractThirty-two composite resections were carried out in the Department of Otolaryngology at Groote Schuur Hospital for oral and oro-pharyngeal squamous carcinoma over the 10-year period, 1977–1986. Three patients were lost to review but all others were followed up to death or to five years. Twenty-seven patients underwent surgery as their primary procedure and five for recurrence after primary radiotherapy. The overall survival was 16 patients at three years and eight at five years. Only one of the five patients who underwent salvage surgery after failed radiotherapy was alive at five years and all five experienced serious postoperative complications. All thosesurviving over five years had had either N0 or N1, disease at the time of presentation for surgery.

Outcomes and xerostomia after postoperative radiotherapy for oral and oropharyngeal carcinoma

Head & Neck ◽  
2014 ◽  
pp. n/a-n/a
Author(s):  
Zhong-He Wang ◽  
Chao Yan ◽  
Zhi-Yuan Zhang ◽  
Chen-Ping Zhang ◽  
Hai-Sheng Hu ◽  
...  
Keyword(s):  
Postoperative Radiotherapy ◽  
Oropharyngeal Carcinoma ◽  
Oral And Oropharyngeal Carcinoma

scholarly journals The Clinical Utility of the Geriatric Nutritional Risk Index in Predicting Postoperative Complications and Long-Term Survival in Elderly Patients with Colorectal Cancer after Curative Surgery

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5852
Author(s):  
Chun-Kai Liao ◽  
Yih-Jong Chern ◽  
Yu-Jen Hsu ◽  
Yueh-Chen Lin ◽  
Yen-Lin Yu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Postoperative Complications ◽  
Independent Risk Factor ◽  
Risk Index ◽  
Nutritional Risk ◽  
Geriatric Nutritional Risk Index ◽  
Curative Surgery ◽  
Term Survival ◽  
Nutritional Risk Index

Research on the relationship between the geriatric nutritional risk index (GNRI) and postoperative complications/oncological outcomes in elderly colorectal cancer (CRC) patients is limited. This study investigated the prognostic value of the GNRI in aged CRC patients. We retrospectively analyzed 1206 consecutive CRC patients aged over 75 years who underwent curative-intent surgery from January 2008 to December 2015 and categorized them into high GNRI (≥98) and low GNRI (<98) groups according to a receiver operating characteristic (ROC) curve analysis. Uni- and multivariate logistic regression analysis were used to explore the association of the GNRI with postoperative complications. Kaplan–Meier survival analyses and the Cox proportional hazard model were used to explore the association between GNRI and survival. We discovered that GNRI is an independent risk factor for postoperative complications (HR: 1.774, p = 0.037). Surgical site infection, wound dehiscence and pneumonia were more common in patients with GNRI < 98. Survival analysis showed significantly worse overall survival and disease-free survival in the low GNRI group (both p < 0.001). In the multivariate analysis, GNRI < 98 was an independent risk factor for OS (HR: 1.329, p = 0.031) and DFS (HR: 1.312, p = 0.034). Thus, preoperative GNRI can be effectively used to predict postoperative complications and long-term survival in elderly CRC patients after curative surgery.

Impact of treatment on quality of life for oral and oropharyngeal carcinoma

2009 ◽  
Vol 38 (10) ◽  
pp. 1052-1058 ◽  
Author(s):  
P. Infante-Cossio ◽  
E. Torres-Carranza ◽  
A. Cayuela ◽  
E. Hens-Aumente ◽  
P. Pastor-Gaitan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oropharyngeal Carcinoma ◽  
Oral And Oropharyngeal Carcinoma

Validity of sentinel node biopsy in early oral and oropharyngeal carcinoma

2018 ◽  
Vol 46 (10) ◽  
pp. 1748-1752 ◽  
Author(s):  
C.G.U. Riese ◽  
J.-A. Karstadt ◽  
A. Schramm ◽  
S. Güleryüz ◽  
G. Dressel ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Oropharyngeal Carcinoma ◽  
Node Biopsy ◽  
Oral And Oropharyngeal Carcinoma

Infectious Postoperative Complications Decrease Long-term Survival in Patients Undergoing Curative Surgery for Colorectal Cancer

2015 ◽  
Vol 261 (3) ◽  
pp. 497-505 ◽  
Author(s):  
Avo Artinyan ◽  
Sonia T. Orcutt ◽  
Daniel A. Anaya ◽  
Peter Richardson ◽  
G. John Chen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Postoperative Complications ◽  
Curative Surgery ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Low Socioeconomic Status Is Associated with Worse Outcomes After Curative Surgery for Colorectal Cancer: Results from a Large, Multicenter Study

2019 ◽  
Vol 24 (11) ◽  
pp. 2628-2636 ◽  
Author(s):  
I. van den Berg ◽  
S. Buettner ◽  
R. R. J. Coebergh van den Braak ◽  
K. H. J. Ultee ◽  
H. F. Lingsma ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Socioeconomic Status ◽  
Postoperative Complications ◽  
Cancer Patients ◽  
Household Income ◽  
Stage I ◽  
Curative Surgery ◽  
Cancer Specific Survival ◽  
Increased Risk ◽  
Percent Increase

Abstract Background Socioeconomic status (SES) has been associated with early mortality in cancer patients. However, the association between SES and outcome in colorectal cancer patients is largely unknown. The aim of this study was to investigate whether SES is associated with short- and long-term outcome in patients undergoing curative surgery for colorectal cancer. Methods Patients who underwent curative surgery in the region of Rotterdam for stage I–III colorectal cancer between January 2007 and July 2014 were included. Gross household income and survival status were obtained from a national registry provided by Statistics Netherlands Centraal Bureau voor de Statistiek. Patients were assigned percentiles according to the national income distribution. Logistic regression and Cox proportional hazard regression were performed to assess the association of SES with 30-day postoperative complications, overall survival and cancer-specific survival, adjusted for known prognosticators. Results For 965 of the 975 eligible patients (99%), gross household income could be retrieved. Patients with a lower SES more often had diabetes, more often underwent an open surgical procedure, and had more comorbidities. In addition, patients with a lower SES were less likely to receive (neo) adjuvant treatment. Lower SES was independently associated with an increased risk of postoperative complications (Odds ratio per percent increase 0.99, 95%CI 0.99–0.998, p = 0.004) and lower cancer-specific mortality (Hazard ratio per percent increase 0.99, 95%CI 0.98–0.99, p = 0.009). Conclusion This study shows that lower SES is associated with increased risk of postoperative complications, and poor cancer-specific survival in patients undergoing surgery for stage I–III colorectal cancer after correcting for known prognosticators.

Impact of postoperative complications on pancreatic cancer survival and recurrence.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 446-446
Author(s):  
Masahiro Asari ◽  
Toru Aoyama ◽  
Yusuke Katayama ◽  
Masaaki Murakawa ◽  
Koichiro Yamaoku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pancreatic Cancer ◽  
Overall Survival ◽  
Postoperative Complications ◽  
Cancer Survival ◽  
Disease Recurrence ◽  
Lymphatic Invasion ◽  
Curative Surgery ◽  
Independent Risk Factors ◽  
The Impact

446 Background: We investigated the impact of postoperative complications on pancreatic cancer survival and recurrence after curative surgery. Methods: This study included 164 patients who underwent curative surgery for pancreatic cancer between 2005 and 2014. The patients were classified into those with postoperative complications (C group) and those without postoperative complications (NC group). The risk factors for overall survival (OS) and recurrence-free survival (RFS) were identified. Results: Postoperative complications were found in 61 of the 164 patients (37.2%). The RFS rate at five years after surgery was 10.6% in the C group patients and was 21.0% in the NC group patients. The RFS tended to be worse in the C group than in the NC group (p=0.1756). The OS rate at five years after surgery was 7.4% in the C group and 22.8% in the NC group, which was significantly different (p=0.0189). The multivariate analysis demonstrated that postoperative complications and lymphatic invasion were significant independent risk factors for the RFS and OS. Conclusions: The development of postoperative complications was a risk factor for a decreased overall survival and for disease recurrence in patients who underwent curative surgery for pancreatic cancer. The surgical procedure, perioperative care and the surgical strategy should be carefully planned to avoid complications.

The impact of preoperative dexamethasone on the postoperative systemic inflammatory response and complications following surgery for colorectal cancer.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 692-692
Author(s):  
Stephen Thomas McSorley ◽  
Paul G. Horgan ◽  
Donald C McMillan
Keyword(s):  
Colorectal Cancer ◽  
Postoperative Complications ◽  
Inflammatory Response ◽  
Elective Surgery ◽  
Systemic Inflammatory Response ◽  
Curative Surgery ◽  
Association Table ◽  
L 14 ◽  
Induction Of Anaesthesia ◽  
The Impact

692 Background: It is now clear that there is a significant association between the magnitude of the systemic inflammatory response and postoperative complications (Adamina et al. Br J Surg 2015;102(6):590-8). The present study examined the impact of preoperative steroids on the postoperative systemic inflammatory response and complications, following elective surgery for colorectal cancer. Methods: The administration of dexamethasone at induction of anaesthesia was prospectively audited from a cohort of patients who underwent elective, potentially curative surgery for colorectal cancer at a single centre between 2008 and 2013. Results: 286 patients were included, of which the majority were male (161, 57%), over 65 (190, 66%) with colonic (183, 64%) and node negative disease (192, 67%). 114 (40%) received dexamethasone at induction of anaesthesia. There was a significant association (Table 1) between preoperative dexamethasone administration and the proportion of patients breaching established CRP thresholds on postoperative days 2 (190mg/L, 14% vs. 50%, p<0.001), and 3 (170mg/L, 27% vs. 49%, p<0.001) but not 4 (145mg/L, 50% vs. 36%, p=0.658). There was no significant association between preoperative dexamethasone and postoperative complications. Conclusions: The present study suggests that the systemic inflammatory response following surgery for colorectal cancer may be attenuated by preoperative steroids. It remains to be determined whether this will lead to a reduction in postoperative complications. [Table: see text]

Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma

1998 ◽  
Vol 132 (1-2) ◽  
pp. 37-44 ◽  
Author(s):  
Shigeharu Fujieda ◽  
Nobuyuki Tanaka ◽  
Hiroshi Sunaga ◽  
Ichiro Noda ◽  
Chizuru Sugimoto ◽  
...  
Keyword(s):  
Oropharyngeal Carcinoma ◽  
In Vitro Chemosensitivity ◽  
Oral And Oropharyngeal Carcinoma
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