Progression of Leukoplakia Lesions Over 13 Years: Final Diagnosis of Proliferative Verrucous Leukoplakia and Oral Cancer

2018 ◽  
Vol 126 (3) ◽  
pp. e85
Author(s):  
Luisa Aguirre Buexm ◽  
Silvia Paula De Oliveira ◽  
Ana Flávia Schueler De Assumpção Leite ◽  
Adriana Terezinha Neves Novellino Alves ◽  
Simone Sant'anna Gonçalves Barbosa ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Final Diagnosis ◽  
Proliferative Verrucous Leukoplakia

scholarly journals Proliferative Verrucous Leukoplakia Revisited: A Retrospective Clinicopathological Study

2021 ◽  
Vol 11 (2) ◽  
pp. 337-346
Author(s):  
Snehashish Ghosh ◽  
Roopa S. Rao ◽  
Manoj K. Upadhyay ◽  
Karuna Kumari ◽  
D. Sharathkumar Sanketh ◽  
...  
Keyword(s):  
Natural History ◽  
Clinical Diagnosis ◽  
Clinical Relevance ◽  
Final Diagnosis ◽  
Disease Entity ◽  
True Nature ◽  
Proliferative Verrucous Leukoplakia ◽  
Clinicopathological Study ◽  
History Of

(1) Objective: To review the criteria proposed by Cerero-Lapiedra et al. and to retrospectively identify the under-diagnosed disease in patients diagnosed with proliferative verrucous leukoplakia. (2) Materials and methods: In this study, we included patients who were diagnosed with leukoplakia (histological label consistent with the clinical diagnosis, n = 95), and cases with a final diagnosis within the spectrum of proliferative verrucous leukoplakia (n = 110) as defined by Batsakis et al. We applied the criteria proposed by Cerero-Lepiedra et al. to screen for the possible cases of proliferative verrucous leukoplakia. (3) Results: Although many of our patients satisfied specific isolated criteria, only 11 cases satisfied specific combinations of the guidelines to satisfy a diagnosis of proliferative verrucous leukoplakia. However, due to the lack of follow-up data, the disease is not confirmed in these 11 cases. (4) Conclusion: A limited number of cases of proliferative verrucous leukoplakia were diagnosed using the criteria given by Cerero-Lapiedra et al. The true natural history of the disease could not be studied due to the lack of follow-up data. (5) Clinical relevance: Proliferative verrucous leukoplakia presenting as hyperkeratosis or mild epithelial dysplasia are often not followed up, and they subsequently transform into carcinoma. Thus, clinicians must be vigilant whenever they encounter leukoplakia, especially with multifocal presentations. In such cases, the follow-up data are the key to understanding the true nature of the disease entity.

scholarly journals Oral lesions detected during a population screening for prevention and early diagnosis of oral cancer and potentially malignant disorders

2020 ◽  
Vol 24 (3) ◽  
pp. 350-354
Author(s):  
Saygo Tomo ◽  
Angela Maria Laurindo Armelin ◽  
Ana Carolina Punhagui Hernandes ◽  
Glauco Issamu Miyahara ◽  
Taís Cristina Nascimento Marques ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Final Diagnosis ◽  
Population Screening ◽  
Oral Medicine ◽  
Oral Potentially Malignant Disorders ◽  
Media Communication ◽  
Prevention Campaign ◽  
Potentially Malignant Disorders ◽  
Specialized Care ◽  
Potentially Malignant

Objective: In this paper, we describe the results of an oral cancer prevention campaign for early detecting and diagnosing oral cancer and potentially malignant disorder. Subjects and method: The population screening was performed in one day in which population was recruited by local mass media communication means. Patients with suspicious lesions were referred for final diagnosis with a specialist in oral medicine andpathology. Results: Of 1.282 patients screened, 104 were referred for specialized care and 94 attended forfinal diagnosis. Of those, only one (1.06%) patient was diagnosed with oral squamous cell carcinoma and25 (26.5%) with oral potentially malignant disorders, while the diagnosis rates for benign conditions andnormality variations were, respectively, 78.7% and 32.9%. Conclusion: These results suggest low awarenessregarding oral cancer within this population, flaws in the knowledge regarding oral cancer by dentists, andthe need for improvements in the access to the at-risk population for oral cancer.

scholarly journals Oral Lesions Diagnosed during Oral Cancer Prevention Campaign in Fernandópolis, Brazil, 2015

2015 ◽  
Vol 6 (3) ◽  
pp. 138-142 ◽  
Author(s):  
Saygo Tomo ◽  
Marlene Cabral Coimbra Cruz ◽  
Karina Gonzales Camara Fernandes ◽  
Mônica Kina ◽  
Nagib Pezati Boer ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Prevention ◽  
Final Diagnosis ◽  
Oral Lesions ◽  
Oral Diseases ◽  
Benign Lesions ◽  
Prevention Campaign ◽  
Diagnosis Rate ◽  
Potentially Malignant ◽  
Suspicious Lesions

ABSTRACT Background To describe oral lesions diagnosed during oral cancer prevention campaign performed in Fernandópolis, Brazil, in 2015. Materials and methods Patients who attended for the Basic Health Units of the city of Fernandópolis on the day of the campaign were examined by dental surgeons who searched for oral lesions clinically suggestive for oral squamous cell carcinoma (SCC) or potentially malignant lesions. Final diagnosis was obtained by a re-evaluation of patients with suspicious lesions performed by an expert in oral diseases. Results Seven hundred and sixty-two patients were examined during the campaign; although 96 (12.59%) presented with oral suspicious lesions and forwarded for re-evaluation, only 72 (9.44%) attended for re-evaluation and got the final diagnosis. Among re-evaluated patients, only 1 (1.38%) was diagnosed with oral SCC, whereas 56 (77.77%) were diagnosed with oral benign lesions, and 19 (26.38%) were diagnosed with oral normality variations. Conclusion Oral cancer low diagnosis rate detected during this campaign might be attributed to lacks on oral cancer prevention campaign methodologies, which clearly needs to be improved aiming to reach patients in real risk for oral cancer development. Furthermore, oral benign lesions diagnosis among patients forwarded with suspicious lesions rates suggests a lack on dental surgeons’ knowledge regarding oral cancer. How to cite this article Tomo S, Cruz MCC, Fernandes KGC, Kina M, Boer NP, Simonato LE. Oral Lesions Diagnosed during Oral Cancer Prevention Campaign in Fernandópolis, Brazil, 2015. World J Dent 2015;6(3):138-142.

Ultrastructural features of prognostic significance in human oral cancer

1992 ◽  
Vol 50 (1) ◽  
pp. 618-619
Author(s):  
Karvita B. Ahluwalia ◽  
Nidhi Sharma
Keyword(s):  
Oral Cancer ◽  
Squamous Cell ◽  
Common Knowledge ◽  
Prognostic Significance ◽  
Growth Control ◽  
Terminal Differentiation ◽  
Squamous Cell Carcinomas ◽  
Effective Therapy ◽  
Invasive Potential ◽  
Biological Behaviour

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.

NSAIDs Halve Oral Cancer in Heavy Smokers

2005 ◽  
Vol 36 (6) ◽  
pp. 7
Author(s):  
Robert Finn
Keyword(s):  
Oral Cancer ◽  
Heavy Smokers

'Oral cancer'-The terminology dilemma

Oral Diseases ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 66-66
Author(s):  
Bernard McCartan
Keyword(s):  
Oral Cancer
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