Effects of collagen membrane application and cortical bone perforation on de novo bone formation in periosteal distraction: an experimental study in a rabbit calvaria

2017 ◽  
Vol 123 (2) ◽  
pp. 173-182 ◽  
Author(s):  
Ken Nakahara ◽  
Maiko Haga-Tsujimura ◽  
Kosaku Sawada ◽  
Matthias Mottini ◽  
Benoit Schaller ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
Cortical Bone ◽  
De Novo ◽  
Collagen Membrane

scholarly journals Effects of hyaluronic acid on bone graft healing: An experimental study on sheep.

2020 ◽  
Vol 3 (2) ◽  
pp. 98-103
Author(s):  
Muhammed Mustafa ◽  
Othman Omar
Keyword(s):  
Experimental Study ◽  
Hyaluronic Acid ◽  
Bone Formation ◽  
Bone Graft ◽  
Bone Graft Substitute ◽  
Control Group ◽  
Collagen Membrane ◽  
Domestic Sheep ◽  
Graft Material ◽  
Basal Bone

Background and Objectives: : Alloplastic is one of known materials have been used to treat bony defects in oral and maxillofacial region, but the healing is much more slower than auto graft . So many interpositional graft materials like hyaluronic acid and bone morphogenetic protein have been introduced to such material to induce osteoinductivity of graft material. This study aimed to evaluate the histological effect of Hyaluronic acid on bone graft substitute. Patients and methods: An experimental study carried out on 3 domestic sheep 2-4 years old. They divided into two groups, first group (study group): bone graft substitute mixed with hyaluronic acid introduced to the created cavities in the basal bone of mandible. Second group (control group): bone graft substitute were introduced into created cavities in the basal bone of mandible and the defects in both groups were covered with collagen membrane. The samples then sacrificed in deferent period interval 2 weeks, 6 weeks and 12 weeks and the sample collected and sent for histological examination. Results: all animals survived till the end of study. Both groups were characterized by new bone formation in defects however the bone formation in group 1 significantly preceded. Conclusion: hyaluronic acid induces the onset of of Oral and Maxillofacial department. Keywords: hyaluronic acid, Bone graft, Alloplastic material, guided bone regeneration.

Early healing of implants placed into fresh extraction sockets: an experimental study in the beagle dog. De novo bone formation

2009 ◽  
Vol 36 (3) ◽  
pp. 265-277 ◽  
Author(s):  
Fabio Vignoletti ◽  
Carina Johansson ◽  
Tomas Albrektsson ◽  
Massimo De Sanctis ◽  
Fidel San Roman ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Formation ◽  
De Novo ◽  
Beagle Dog ◽  
Early Healing

Bone tissue engineering in the greater omentum with computer-aided design/computer-aided manufacturing scaffolds is enhanced by a periosteum transplant

2020 ◽  
Author(s):  
Hendrik Naujokat ◽  
Klaas Loger ◽  
Juliane Schulz ◽  
Yahya Açil ◽  
Jörg Wiltfang
Keyword(s):  
Bone Formation ◽  
Bone Tissue ◽  
Computer Aided Design ◽  
Bone Tissue Regeneration ◽  
Histological Evaluation ◽  
Greater Omentum ◽  
Collagen Membrane ◽  
Computer Aided ◽  
3D Printed ◽  
The Impact

Aim: This study aimed to evaluate two different vascularized bone flap scaffolds and the impact of two barrier membranes for the reconstruction of critical-size bone defects. Materials & methods: 3D-printed scaffolds of biodegradable calcium phosphate and bioinert titanium were loaded with rhBMP-2 bone marrow aspirate, wrapped by a collagen membrane or a periosteum transplant and implanted into the greater omentum of miniature pigs. Results: Histological evaluation demonstrated significant bone formation within the first 8 weeks in both scaffolds. The periosteum transplant led to enhanced bone formation and a homogenous distribution in the scaffolds. The omentum tissue grew out a robust vascular supply. Conclusion: Endocultivation using 3D-printed scaffolds in the greater omentum is a very promising approach in defect-specific bone tissue regeneration.

scholarly journals Maxillary Sinus Augmentation Using Ceramic Alloplastic Granules or Paste: An Experimental Study in Rabbits

2021 ◽  
Vol 9 (6) ◽  
pp. 65
Author(s):  
Michael Medeiros Costa ◽  
Daniele Botticelli ◽  
Ofer Moses ◽  
Yuki Omori ◽  
Shigeo Fujiwara ◽  
...  
Keyword(s):  
Bone Formation ◽  
Maxillary Sinus ◽  
Biological Behavior ◽  
Collagen Membrane ◽  
Alloplastic Material ◽  
New Bone Formation ◽  
Sinus Augmentation ◽  
Beta Tricalcium Phosphate ◽  
Sinus Lifting ◽  
Points Of View

Background: Due to the lack of data comparing the biological behavior of two formulations, granules and paste, of alloplastic graft from microtomographic and histomorphometric points of view, the aim of the present experiment was to compare the histomorphometric and microtomographic healing of two formulations, i.e., granules (MR sites) or paste (MR-inject sites) of an alloplastic graft composed of a combination of beta-tricalcium phosphate and hydroxyapatite used for maxillary sinus lifting. Methods: A sinus lifting procedure was carried out bilaterally in 20 rabbits, and the elevated space was filled with either paste or granules of an alloplastic material. A collagen membrane was placed on the antrostomy and the animals were euthanized after 2 or 10 weeks, 10 animals each group. Microtomographic and histological analyses were performed. Results: Higher proportions of new bone formation were found at the MR, compared to the MR-inject sites both after 2 weeks (2.65 ± 2.89% vs. 0.08 ± 0.12%; p < 0.01) and 10 weeks of healing (34.20 ± 13.86 vs. 23.28 ± 10.35%; p = 0.022). Conclusions: It was concluded that new bone formation was faster in the MR sites, compared to the MR-inject. However, a longer time of healing should be allowed to make final conclusions about the efficiency in bone formation of the paste formulation of the biomaterial used in the present study.

A novel multiphase anodic spark deposition coating for the improvement of orthopedic implant osseointegration: An experimental study in cortical bone of sheep

2008 ◽  
Vol 85A (4) ◽  
pp. 1022-1031 ◽  
Author(s):  
Gianluca Giavaresi ◽  
Milena Fini ◽  
Roberto Chiesa ◽  
Carmen Giordano ◽  
Enrico Sandrini ◽  
...  
Keyword(s):  
Experimental Study ◽  
Cortical Bone ◽  
Orthopedic Implant

Evaluation of autogenous PRGF+β-TCP with or without a collagen membrane on bone formation and implant osseointegration in large size bone defects. A preclinicalin vivostudy

2015 ◽  
Vol 27 (8) ◽  
pp. 981-987 ◽  
Author(s):  
Leonidas Batas ◽  
Andreas Stavropoulos ◽  
Serafim Papadimitriou ◽  
Jens R. Nyengaard ◽  
Antonios Konstantinidis
Keyword(s):  
Bone Formation ◽  
Bone Defects ◽  
Collagen Membrane ◽  
Large Size
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