DIFFUSION REFLECTION, A NOVEL METHOD FOR DISCRIMINATING ORAL CANCER AND POTENTIAL MALIGNANT DISORDERS FROM BENIGN LESIONS

2016 ◽  
Vol 122 (5) ◽  
pp. e158-e159
Author(s):  
A. Hirshberg ◽  
I. Alon ◽  
R. Ankri ◽  
D. Fixler
Keyword(s):  
Oral Cancer ◽  
Benign Lesions ◽  
Diffusion Reflection ◽  
Novel Method

scholarly journals Non-Invasive Diagnostic System Based on Light for Detecting Early-Stage Oral Cancer and High-Risk Precancerous Lesions—Potential for Dentistry

Cancers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3185
Author(s):  
Seiko Tatehara ◽  
Kazuhito Satomura
Keyword(s):  
Oral Cancer ◽  
Aminolevulinic Acid ◽  
Early Stage ◽  
Diagnostic Methods ◽  
Epithelial Dysplasia ◽  
Benign Lesions ◽  
Oral Health Promotion ◽  
Oral Epithelial Dysplasia ◽  
Non Invasive ◽  
Oral Epithelial

Oral health promotion and examinations have contributed to the early detection of oral cancer and oral potentially malignant disorders, leading to the adaptation of minimally invasive therapies and subsequent improvements in the prognosis/maintenance of the quality of life after treatments. However, the accurate detection of early-stage oral cancer and oral epithelial dysplasia is particularly difficult for conventional oral examinations because these lesions sometimes resemble benign lesions or healthy oral mucosa tissues. Although oral biopsy has been considered the gold standard for accurate diagnosis, it is deemed invasive for patients. For this reason, most clinicians are looking forward to the development of non-invasive diagnostic technologies to detect and distinguish between cancerous and benign lesions. To date, several non-invasive adjunctive fluorescence-based detection systems have improved the accuracy of the detection and diagnosis of oral mucosal lesions. Autofluorescence-based systems can detect lesions as a loss of autofluorescence through irradiation with blue-violet lights. Photodynamic diagnosis using 5-aminolevulinic acid (ALA-PDD) shows the presence of very early oral cancers and oral epithelial dysplasia as a red fluorescent area. In this article, currently used fluorescence-based diagnostic methods are introduced and discussed from a clinical point of view.

scholarly journals EDNRB and DCC Salivary Rinse Hypermethylation Has a Similar Performance as Expert Clinical Examination in Discrimination of Oral Cancer/Dysplasia versus Benign Lesions

2013 ◽  
Vol 19 (12) ◽  
pp. 3268-3275 ◽  
Author(s):  
Juliana Schussel ◽  
Xian Chong Zhou ◽  
Zhe Zhang ◽  
Kavita Pattani ◽  
Francisco Bermudez ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Clinical Examination ◽  
Benign Lesions ◽  
Similar Performance

Oral cancer adjacent to dental implants mimicking benign lesions: a case series study

2020 ◽  
Author(s):  
Marisol Miranda Galvis ◽  
Isabel Schausltz Pereira Faustino ◽  
Joab Cabral Ramos ◽  
Alan Roger Santos Silva ◽  
Fábio Abreu Alves ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Dental Implants ◽  
Case Series ◽  
Benign Lesions ◽  
Case Series Study ◽  
Series Study

A novel method of intra-arterial chemotherapy for oral cancer.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e18086-e18086
Author(s):  
Masatoshi Ohmae ◽  
Itsuro Kato ◽  
Yusei Fujita ◽  
Noritoshi Meshii ◽  
Ayako Motoki ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Novel Method

scholarly journals Oral Lesions Diagnosed during Oral Cancer Prevention Campaign in Fernandópolis, Brazil, 2015

2015 ◽  
Vol 6 (3) ◽  
pp. 138-142 ◽  
Author(s):  
Saygo Tomo ◽  
Marlene Cabral Coimbra Cruz ◽  
Karina Gonzales Camara Fernandes ◽  
Mônica Kina ◽  
Nagib Pezati Boer ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Prevention ◽  
Final Diagnosis ◽  
Oral Lesions ◽  
Oral Diseases ◽  
Benign Lesions ◽  
Prevention Campaign ◽  
Diagnosis Rate ◽  
Potentially Malignant ◽  
Suspicious Lesions

ABSTRACT Background To describe oral lesions diagnosed during oral cancer prevention campaign performed in Fernandópolis, Brazil, in 2015. Materials and methods Patients who attended for the Basic Health Units of the city of Fernandópolis on the day of the campaign were examined by dental surgeons who searched for oral lesions clinically suggestive for oral squamous cell carcinoma (SCC) or potentially malignant lesions. Final diagnosis was obtained by a re-evaluation of patients with suspicious lesions performed by an expert in oral diseases. Results Seven hundred and sixty-two patients were examined during the campaign; although 96 (12.59%) presented with oral suspicious lesions and forwarded for re-evaluation, only 72 (9.44%) attended for re-evaluation and got the final diagnosis. Among re-evaluated patients, only 1 (1.38%) was diagnosed with oral SCC, whereas 56 (77.77%) were diagnosed with oral benign lesions, and 19 (26.38%) were diagnosed with oral normality variations. Conclusion Oral cancer low diagnosis rate detected during this campaign might be attributed to lacks on oral cancer prevention campaign methodologies, which clearly needs to be improved aiming to reach patients in real risk for oral cancer development. Furthermore, oral benign lesions diagnosis among patients forwarded with suspicious lesions rates suggests a lack on dental surgeons’ knowledge regarding oral cancer. How to cite this article Tomo S, Cruz MCC, Fernandes KGC, Kina M, Boer NP, Simonato LE. Oral Lesions Diagnosed during Oral Cancer Prevention Campaign in Fernandópolis, Brazil, 2015. World J Dent 2015;6(3):138-142.

The removal and morphology of intact biofilms from implanted venous access devices

1995 ◽  
Vol 53 ◽  
pp. 1020-1021
Author(s):  
M.A. Gregory ◽  
G.P. Hadley
Keyword(s):  
Patient Selection ◽  
Surgical Oncology ◽  
Venous Access ◽  
Common Procedure ◽  
Indwelling Catheters ◽  
Careful Patient ◽  
Novel Method ◽  
The Subject ◽  
Vascular Catheters ◽  
Venous Access Devices

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.

Ultrastructural features of prognostic significance in human oral cancer

1992 ◽  
Vol 50 (1) ◽  
pp. 618-619
Author(s):  
Karvita B. Ahluwalia ◽  
Nidhi Sharma
Keyword(s):  
Oral Cancer ◽  
Squamous Cell ◽  
Common Knowledge ◽  
Prognostic Significance ◽  
Growth Control ◽  
Terminal Differentiation ◽  
Squamous Cell Carcinomas ◽  
Effective Therapy ◽  
Invasive Potential ◽  
Biological Behaviour

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.

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