Immunoexpression of Tumor-Associated Macrophages Subpopulation M2 in Lower Lip Squamous Cell Carcinomas

2015 ◽  
Vol 120 (2) ◽  
pp. e97
Author(s):  
JANAINA ALMEIDA MESQUITA ◽  
PRISCILLA SUASSUNA CARNEIRO LÚCIO ◽  
DANIELA COTTA RIBEIRO ◽  
MARIA CÁSSIA FERREIRA DE AGUIAR ◽  
POLLIANNA MUNIZ ALVES ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Tumor Associated Macrophages ◽  
Lower Lip

scholarly journals Tumor-associated macrophages (TAMs): clinical-pathological parameters in squamous cell carcinomas of the lower lip

2016 ◽  
Vol 30 (1) ◽  
Author(s):  
Priscilla Suassuna Carneiro LÚCIO ◽  
Daniela Cotta RIBEIRO ◽  
Maria Cássia Ferreira de AGUIAR ◽  
Pollianna Muniz ALVES ◽  
Cassiano Francisco Weege NONAKA ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Tumor Associated Macrophages ◽  
Lower Lip

Characterization of Tumor-Associated Macrophages Subpopulation M1 and Their Relationship With Clinicopathological Parameters in Lower Lip Squamous Cell Carcinomas

2015 ◽  
Vol 120 (2) ◽  
pp. e83
Author(s):  
ARLLEY DE SOUSA LEITÃO ◽  
PRISCILLA SUASSUNA CARNEIRO LÚCIO ◽  
DANIELA COTTA RIBEIRO ◽  
MARIA CÁSSIA FERREIRA DE AGUIAR ◽  
POLLIANNA MUNIZ ALVES ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Clinicopathological Parameters ◽  
Tumor Associated Macrophages ◽  
Lower Lip

scholarly journals Collagen IV and laminin expression in squamous cell carcinomas of lower lip and tongue

2016 ◽  
Vol 19 (2) ◽  
pp. 82
Author(s):  
João Luiz de Miranda ◽  
Dhelfeson Willya Douglas de Oliveira ◽  
Rafael Menezes-Silva ◽  
Roseana De Almeida Freitas
Keyword(s):  
Basement Membrane ◽  
Squamous Cell ◽  
Immunohistochemical Analysis ◽  
Collagen Iv ◽  
Squamous Cell Carcinomas ◽  
Matrix Proteins ◽  
Biological Behavior ◽  
Collagen Type Iv ◽  
Lower Lip ◽  
Type Iv

<p class="western" align="justify"><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>O</strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>bjective: </strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">In this study, the expression of the extracellular matrix proteins was immunohistochemically studied and compared with the histological grading of squamous cell carcinomas of the lower lip and tongue. </span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>Material and M</strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>ethods: </strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">The lower lip carcinomas (n=12) and the tongue carcinomas (n=12) were histopathologically graduated according to Bryne’s method. The immunohistochemical technique utilized specific antibodies to collagen IV and laminin. Histopathologic and immunohistochemical analysis were carried-out on the tumoral invasive front. </span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>R</strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>esults: </strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">Most of lower lip carcinomas (91.7%) was classified in lower score and all tongue carcinomas (100%) in high score malignant grade (p&lt;0.01). Collagen type IV expression was absent in the peritumoral basement membrane in 50% of lower lip carcinomas and in 66.7% of tongue carcinomas (p=0.09). Laminin expression was absent in the peritumoral basement membrane in 66.7% of lower lip carcinomas and in 58.3% of tongue carcinomas (p=0.48). When these two glicoproteins were expressed, they showed a linear, thin and discontinuous pattern and a weak intensity of expression. </span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>C</strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>onclusion: </strong></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">The high score malignancy grade of the tongue carcinomas associated with the expression pattern of the studied matrix proteins. It suggests that tongue squamous cell carcinomas have more invasive potential and more aggressive biological behavior than the lower lip carcinomas.</span></span></span></p><p class="western" lang="en-US" align="justify"> </p><p class="western" align="justify"><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong>Keywords</strong></span></span></span></p><p class="western" align="justify"><span style="font-family: Arial, serif;"><span><span lang="en-US">C</span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">ollagen type IV; Laminin; </span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">C</span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">arcinoma; </span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">I</span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">mmunohistochemistry.</span></span></span></p><p> </p>

scholarly journals Immunohistochemical analysis of FoxP3+ regulatory T cells in lower lip squamous cell carcinomas

2016 ◽  
Vol 30 (1) ◽  
Author(s):  
Fernando Antonio Portela da CUNHA FILHO ◽  
Maria Cássia Ferreira de AGUIAR ◽  
Lélia Batista de SOUZA ◽  
Leão PEREIRA PINTO ◽  
Gustavo Pina GODOY ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Squamous Cell ◽  
Immunohistochemical Analysis ◽  
Squamous Cell Carcinomas ◽  
Lower Lip
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