Pemphigus Vulgaris With Oral Mucosa and Skin Involvement: A Case Report

2015 ◽  
Vol 120 (2) ◽  
pp. e57
Author(s):  
PEDRO EVERTON MARQUES GOES ◽  
ANIBAL HENRIQUE BARBOSA LUNA ◽  
LUDMILA SILVA DE FIGUEIREDO ◽  
EDUARDO DE ALMEIDA SOUTO MONTENEGRO ◽  
KAROLINE GOMES DA SILVEIRA ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Pemphigus Vulgaris ◽  
Skin Involvement

scholarly journals Pemphigus Vulgaris Confined to the Gingiva: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Mitsuhiro Ohta ◽  
Seiko Osawa ◽  
Hiroyasu Endo ◽  
Kayo Kuyama ◽  
Hirotsugu Yamamoto ◽  
...  
Keyword(s):  
Case Report ◽  
Lichen Planus ◽  
Oral Mucosa ◽  
Pemphigus Vulgaris ◽  
Oral Lesions ◽  
Skin Involvement ◽  
Mucous Membranes ◽  
History Of ◽  
Blistering Disease ◽  
One Year

Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral mucosa is frequently affected in patients with PV, and oral lesions may be the first sign of the disease in majority of patients. In some patients, oral lesions may also be followed by skin involvement. Therefore, timely recognition and therapy of oral lesions is critical as it may prevent skin involvement. Early oral lesions of PV are, however, often regarded as difficult to diagnose, since the initial oral lesions may be relatively nonspecific, manifesting as superficial erosions or ulcerations, and rarely presenting with the formation of intact bullae. Lesions may occur anywhere on the oral mucosa including gingiva; however; desquamtive gingivitis is less common with PV than other mucocutaneous conditions such as pemphigoid or lichen planus. This paper describes the case of a patient presenting with a one-year history of painful gingival, who is finally diagnosed as having PV.

scholarly journals MANIFESTASI DAN PENATALAKSANAAN PEMFIGUS VULGARIS DI RONGGA MULUT

2018 ◽  
Vol 2 (2) ◽  
pp. 117-124
Author(s):  
Indra Gunawan ◽  
Riani Setiadhi
Keyword(s):  
Case Report ◽  
Early Recognition ◽  
Pemphigus Vulgaris ◽  
Oral Lesions ◽  
Oral Manifestations ◽  
Skin Involvement ◽  
Mucous Membranes ◽  
Blistering Disease ◽  
Mouth Wash ◽  
Desmoglein 3

Background : Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral lesions could be the first sign of the disease followed by the involvement of skin and other mucosa sites.Objectives : This is oral manifestations of pemphigus vulgaris case report, intended to help clinicians to recognize and treat the oral lesions.Case Reported : Male 27 yo admitted to RSUP Dr.Hasan Sadikin hospital with multiple blisters on the skin and oral mucosa, was diagnosed with Pemphigus Vulgaris.Case Management : Patient was treated with steroid mouth wash and oral paste. After two months of treatment, the patient was fully recovered from oral lesion.Discussion : In PV, autoantibodies are produced against desmosomes spesifically desmoglein 3 which responsible for holding the cells of the epithelium together. The loss of adhesive function due to anti Dsg 3 antibodies result in bulla formation on the oral mucosa.The aetiology for PV is still uncertain. Conclusion :Early recognition and treatment of oral lesions is important as it may prevent skin involvement. Early treatment, patient’s compliance and multi disciplinal teamwork ensure the treatment succes for this disease

scholarly journals Labial vitiligo associated with a factice disorder: a case report

2018 ◽  
Vol 24 (4) ◽  
pp. 167-169
Author(s):  
Margaux Fricain ◽  
Pierre Weidmann ◽  
Yvon Roche ◽  
Jean Christophe Fricain
Keyword(s):  
Folic Acid ◽  
Case Report ◽  
Vitamin C ◽  
Oral Mucosa ◽  
Clinical Examination ◽  
North Africa ◽  
Skin Involvement ◽  
Upper Lip ◽  
Immune Disease ◽  
Sharp Edges

Introduction: Vitiligo is a non-contagious leukoderma. The loss of melanocytes result in a local hypopigmentation like white symmetrical plaques with sharp edges, most of the time surrounded by hyperpigmentation. It might be an auto immune disease with a genetic predisposition linked to psychological disorders. Oral mucosa vitiligo has rarely been described in the literature. Observation: A seventeen years old patient, native from North Africa, has consulted for a half left upper lip depigmentation appeared in October 2016. The dermatologist had made the diagnosis of vitiligo and prescribed vitamin C and folic acid, without any result. In July 2017, as the lesion has extended to the whole upper lip, the patient came to oral mucosa pathology consultation. Anamnesis revealed a chronic lips chewing. Clinical examination revealed a linear vermillion border depigmentation of the upper lip associated with peripheral pigment enhancement, as well as digital cutaneous involvement. The prescribed treatment was: tacrolimus 0.1% twice daily in local application, stopping practice disorder and sun protection. Comment: Diagnosis of vitiligo is based on clinical examination that can differentiate a segmental vitiligo (localized on at least one dermatomes) of a non-segmental vitiligo (acrofacial, generalized, universalis). Vitiligo of the oral mucosa is rare. It has mainly been described in India. Oral mucosa involvement would affect 55% of patient and the lip would be affected in almost one in two cases in this population. Conclusion: Oral mucosa vitiligo must be known by oral surgeon who has to master the diagnosis and treatments in association with dermatologist, given the concomitant skin involvement that is almost mandatory.

scholarly journals Phemphigus vulgaris an autoimmune acantholysis: a case report

2020 ◽  
Vol 6 (6) ◽  
pp. 801
Author(s):  
Abarna Lakshmi Ravi ◽  
Rajganesh Ravichandran ◽  
Nikhil Cherian Sam ◽  
Jaya Shree Dilibatcha ◽  
Raveena Pachal Balakrishnan
Keyword(s):  
Monoclonal Antibodies ◽  
Case Report ◽  
Oral Mucosa ◽  
Male Patient ◽  
Skin Disease ◽  
Pemphigus Vulgaris ◽  
Good Recovery ◽  
Clear Fluid ◽  
The Face ◽  
Epithelial Layers

<p class="abstract">Pemphigus vulgaris is a rare chronic autoimmune skin disease characterized by a flaccid blister filled with clear fluid that arises on the skin or an erythematous base. The keratinocytes separated by the desmoglein present on the desmosomes which clinically manifests as fluid-filled blisters on the skin. We present pemphigus vulgaris with an unknown cause but good recovery after the management with monoclonal antibodies and corticosteroids in a 30-year-old male patient who came to the hospital with complaints of blisters on the epithelial layers of skin on the face and oral mucosa.</p>

Childhood pemphigus vulgaris treated with dapsone: a case report.

1998 ◽  
Vol 15 (5) ◽  
pp. 381-383 ◽  
Author(s):  
B Bjarnason ◽  
C Skoglund ◽  
E Flosadottir
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris

Chronic Pemphigus Vulgaris of the Gingiva: A Case Report With a 6-Year Follow-up

1983 ◽  
Vol 54 (11) ◽  
pp. 685-689 ◽  
Author(s):  
Walter A. Orlowski ◽  
Edward Bressman ◽  
John L. Doyle ◽  
Abram I. Chasens
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris
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