p16INK4 Expression is not associated with human papillomavirus in oral lichen planus

2014 ◽  
Vol 118 (6) ◽  
pp. 694-702 ◽  
Author(s):  
Lucio Montebugnoli ◽  
Davide B. Gissi ◽  
Luca Scapoli ◽  
Annalisa Palmieri ◽  
Luca Morandi ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Lichen

scholarly journals Association of Human Papillomavirus With Oral Lichen Planus and Oral Leukoplakia: A Meta-analysis

2020 ◽  
Vol 20 (4) ◽  
pp. 101485
Author(s):  
Qianhui Shang ◽  
Jiakuan Peng ◽  
Yu Zhou ◽  
Qianming Chen ◽  
Hao Xu
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Meta Analysis ◽  
Oral Leukoplakia ◽  
Oral Lichen

scholarly journals Peripheral and Local Human Papillomavirus 16–Specific CD8 + T-Cell Expansions Characterize Erosive Oral Lichen Planus

2015 ◽  
Vol 135 (2) ◽  
pp. 418-424 ◽  
Author(s):  
Manuelle Viguier ◽  
Hervé Bachelez ◽  
Béatrice Poirier ◽  
Jérémy Kagan ◽  
Maxime Battistella ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
T Cell ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Cd8 T Cell ◽  
Human Papillomavirus 16 ◽  
Oral Lichen

scholarly journals The Magnitude of the Association between Human Papillomavirus and Oral Lichen Planus: A Meta-Analysis

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0161339 ◽  
Author(s):  
Junxian Ma ◽  
Jinshan Zhang ◽  
Yan Zhang ◽  
Tingting Lv ◽  
Jie Liu
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Meta Analysis ◽  
Oral Lichen

scholarly journals Risk co-factors inducing malignant transformation of oral lichen planus: A literature review of clinical studies

2021 ◽  
Vol 5 (1) ◽  
pp. 005-011
Author(s):  
Saleh Wafaa ◽  
Youssef Jilan M ◽  
Ata Fatma ◽  
Anees Mohamed M ◽  
Cha Seunghee ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Hepatitis C ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Potential Risk ◽  
Clinical Studies ◽  
Animal Studies ◽  
Oral Lichen Planus ◽  
Chronic Inflammatory Disease ◽  
Oral Lichen

Oral lichen planus (OLP) is an autoimmune chronic inflammatory disease. The potential risk of malignant transformation in OLP remains controversial. The aim of the present study was to review original clinical studies published in indexed databases, which assessed the potential risk cofactors which were implicated in the malignant transformation of oral lichen planus. We focused our search to include most of the studies that reported malignant transformation of oral lichen planus using different combinations of the following key indexing terms: oral lichen planus, malignant transformation, smoking, alcohol, chronic inflammation, candida, human papillomavirus (HPV), hepatitis C virus (HCV) and immunosuppression. The animal studies were excluded from our study. Despite a dearth of studies on this topic we have identified consumption of tobacco and/or alcohol, the presence of erosive and/or atrophic areas, infection with candida, HCV, HPV, and immunosuppression as significant cofactors. Patients with OLP with these risk co-factors are at risk of malignant transformation should, therefore be followed up for an extensive period or even for life.

scholarly journals Molecular Detection of Human Papillomavirus DNA in Oral Lichen Planus Patients

2019 ◽  
Author(s):  
Ayesha Sameera ◽  
Rosaiah Kotikalpudi ◽  
Rajesh Kumar Patel ◽  
Kranti Kiran Reddy ◽  
MD Prasanna ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Molecular Detection ◽  
Oral Lichen ◽  
Papillomavirus Dna

scholarly journals Oral Lichen Planus in Thai Patients Has a Low Prevalence of Human Papillomavirus

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Pratanporn Arirachakaran ◽  
Jira Chansaengroj ◽  
Woradee Lurchachaiwong ◽  
Patnarin Kanjanabud ◽  
Kobkan Thongprasom ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Cell Function ◽  
Hpv Infection ◽  
Predisposing Factor ◽  
Hpv Dna ◽  
Tissue Biopsy ◽  
Low Prevalence ◽  
Oral Lichen

Background. Oral lichen planus (OLP) is a common chronic inflammatory immune-mediated disease, with an etiopathogenesis associated with cell-mediated immunological dysfunction. Viral infection has been hypothesized as a predisposing factor in the pathogenesis of this disease. Viruses may alter host cell function by inducing the abnormal expression of cellular proteins leading to disease development. However, reports on the relationship between human papillomavirus (HPV) and OLP are inconclusive. Objective. To explore the association between HPV and OLP in Thai patients. Materials and Methods. DNA was extracted from thirty-seven fresh-frozen tissue biopsy specimens from OLP lesions, and polymerase chain reaction assay for the L1 and E1 genes covering 32 types of high- and low-risk HPV was performed. Results. HPV DNA was detected in one tissue biopsy from an atrophic-type OLP lesion. All control samples were negative. Genomic sequencing of the E1 gene PCR product demonstrated that the HPV-type 16 found in the lesion is closely related to the East Asian type. Conclusion. Our data indicate a low prevalence of HPV infection in OLP lesions in Thai patients.

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