A case of lichen planus in a pediatric patient: Clinical presentation and management

Author(s):  
MARIANA CARVALHO XEREZ ◽  
KATIANNE SOARES RODRIGUES ◽  
CAIO CéSAR DA SILVA BARROS ◽  
ANTôNIO DE LISBOA LOPES COSTA ◽  
MáRCIA CRISTINA DA COSTA MIGUEL ◽  
...  

2018 ◽  
Vol 37 (02) ◽  
pp. 119-122
Author(s):  
Miguel Maldonado-Morán ◽  
Jeisson Ospina ◽  
Juan Vega ◽  
Claudia Restrepo ◽  
Daniela Rico ◽  
...  

AbstractPituicytoma is a rare tumor that arises from the glial cells of the neurohypophysis. For a long time, it was believed that pituicytomas only appeared in adults. Currently, at least three cases of this entity occurring in children have been reported in the literature. The aim of the present report is to describe the case of a 5-year-old girl who presented to the emergency department with visual disturbances, and the diagnosis was a recurrent pituicytoma. Therefore, the clinical presentation, the radiological features of the tumor, and the corresponding surgical management are described. Additionally, a brief review of the management of this unusual entity was performed.


Biology ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1129
Author(s):  
Anna Baran ◽  
Julia Nowowiejska ◽  
Tomasz W. Kamiński ◽  
Julita A. Krahel ◽  
Iwona Flisiak

Plaque psoriasis (PSO) and lichen planus (LP) are skin diseases with some similarities in pathogenesis, comorbidities, and clinical presentation. Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and its ligand, α4β7 integrin, are involved in inflammatory bowel diseases and liver dysfunctions, which occur more frequently in PSO and LP. Serum MAdCAM-1 and ITGB7 levels in patients with plaque PSO and eruptive LP have never been studied before. The study included 42 patients with PSO, 13 with LP, and 23 controls. Serum molecules levels were evaluated using the immune–enzymatic method. ITGB7 concentration was not statistically different, both in patients with PSO and LP, compared to controls (both p > 0.05). MAdCAM-1 level was significantly lower in PSO subjects than in controls (p = 0.041), whereas in the LP group, a downward trend was observed (p = 0.088) with p = 0.0455 in ANOVA. Multiple linear regression revealed independent associations between ITGB7 and HDL and BMI and RBC in the LP group. In psoriatic patients with elevated CRP, there was an upward trend for MAdCAM-1, and also a positive correlation between MAdCAM-1 and WBC. ITGB7 and MAdCAM-1 cannot serve as markers of disease activity or liver pathology neither in patients with PSO nor LP. MAdCAM-1 might play a role as an inflammation indicator in PSO and a beneficial influence on the lipid profile in LP.


2009 ◽  
Vol 21 (3) ◽  
Author(s):  
Ameta Primasari

Lichen planus is a common oral disorder which may represent the manifestation of varies clinical presentation and microscopic findings. In this retrospective study of 86, cases of oral lichen planus (OLP) were compared with 73 cases of oral lichenoid lesions (OLL). Various clinicohistopathological features were studied. The object of this study was to compare clinical and microscopic findings in order to present evidence that supports the position of true lichen planus. Biopsy specimens were obtained from every patient. The biopsy specimens were fixed in 10 percent formalin, embedded in paraffin, sectioned at 4 microns and stained by means of routine hemotoxylin and eosin procedures. The histologic specimens were examined and evaluated without knowledge of clinical findings. The mean age at presentation of patients with OLP was 42.5 years as compared to 47.0 years for OLL. There was no significant difference between the ethnic groups, site of lesions and the distribution of the clinical presentation. Compare to histopathologic findings, there were only 55% clinical and histological agreement in this study, this because of using strict criteria for oral lichen planus there could be an over diagnosis lesions. This study showed that there were no reliable clinical and histopathological features which could differentiate OLL from OLP. The features in the OLL group were non specific. The patient’s medical history, oral habits or psychological status appeared to be able to alter the classical clinicopathological findings.


2020 ◽  
Vol 4 (10) ◽  
pp. 617-624
Author(s):  
O.V. Parygina ◽  
◽  
I.O. Smirnova ◽  
M.V. Oganesyan ◽  
Y.G. Petunova ◽  
...  

Lichenoid vulvar dermatoses are a heterogeneous group of diseases characterized by a number of overlapping signs and/or morphological features. Clinical similarity is accounted for by the appearance of small discrete papules with closely adjacent superficial squamae. The prototype of lichenoid dermatoses is lichen ruber planus. Histologically, lichenoid pattern is characterized by basal epithelial cell damage and a band-like infiltrate in the upper dermis. The International Society on Vulvovaginal Diseases categorizes lichen ruber planus and early lichen sclerosus as dermatoses with this histological pattern. Some authors also classify plasma cell (Zoon) vulvitis as lichenoid vulvar dermatoses. The cause of diagnostic errors lies in the similarity of the clinical and histological presentations of lichenoid vulvar dermatoses. Dermatoscopy should be considered as an additional diagnostic test. Only few studies address the key dermatoscopic signs of vulvar dermatoses. Histological study is important for the differential diagnosis. However, at some stages of disease evolution, vulvar dermatoses can have an overlapping histological pattern. This paper summarizes the data on the clinical, histological, and dermatoscopic presentation of the most common lichenoid vulvar dermatoses, i.e., lichen planus, lichen sclerosus, lichen simplex chronicus, and plasma cell vulvitis. KEYWORDS: lichenoid dermatoses, vulvar dermatoses, lichen sclerosus, lichen planus, lichen simplex chronicus, plasma cell vulvitis, Zoon vulvitis, dermoscopy. FOR CITATION: Parygina O.V., Smirnova I.O., Oganesyan M.V. et al. Lichenoid vulvar dermatoses: clinical presentation, morphology, and dermatoscopic signs. Russian Medical Inquiry. 2020;4(10):617–624. DOI: 10.32364/2587-6821-2020-4-10-617-624.


2021 ◽  
pp. 109352662110438
Author(s):  
Joshua M Eisenberg ◽  
Joseph A Buckwalter V ◽  
Anthony N Snow ◽  
Jonathan Davick

Cellular fibroma of tendon sheath (CFTS) is a rare, benign myofibroblastic neoplasm of tenosynovial soft tissues closely resembling nodular fasciitis (NF), but is histomorphologically distinct from classic fibroma of tendon sheath (FTS). We report a case of a pediatric patient with thumb swelling clinically concerning for arthritis with a biopsy demonstrating myofibroblastic proliferation with features consistent with NF/CFTS, and molecular studies confirming the presence of a USP6 gene fusion (TNC-USP6). This case highlights a unique clinical presentation of CFTS in a pediatric patient mimicking an inflammatory or reactive/non-neoplastic musculoskeletal disorder and the increasingly crucial role of molecular testing to differentiate a reactive myofibroblastic process from a neoplasm. Moreover, this report identifies TNC as a new fusion partner to USP6 fusion partner adding to our growing understanding of the USP6-rearranged family of tumors.


2005 ◽  
Vol 1 (1) ◽  
pp. 148
Author(s):  
L. Montebupoli ◽  
L. Dovizioso ◽  
A. Cuppini ◽  
M.P. Foschini ◽  
A. Farnedi ◽  
...  

2018 ◽  
Vol 59 (3) ◽  
pp. e208-e210 ◽  
Author(s):  
Prachi C Gajjar ◽  
Hita H Mehta ◽  
Vivek Nimbark ◽  
Manisha Jethwa

1979 ◽  
Vol 87 (2) ◽  
pp. 199-202 ◽  
Author(s):  
Allan B. Seid ◽  
Dan Millet ◽  
Robin Cotton

Nasotracheal intubation has been well established as a method for maintaining an artificial airway in children. Approximately 0.5% to 1.0% of cases have complications that require surgical intervention to correct the laryngeal trauma. A complication described as protrusion of the laryngeal ventricle following nasotracheal intubation is reported. The clinical presentation and a rationale for the treatment plan are discussed.


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