The role of direct visual fluorescent examination (VELscope) in routine screening for potentially malignant oral mucosal lesions

2012 ◽  
Vol 114 (5) ◽  
pp. 636-643 ◽  
Author(s):  
Kristin K. McNamara ◽  
Brent D. Martin ◽  
Erik W. Evans ◽  
John R. Kalmar
Keyword(s):  
Routine Screening ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant ◽  
Mucosal Lesions

scholarly journals Prevalence of Potentially Malignant Oral Mucosal Lesions among Tobacco Users in Jeddah, Saudi Arabia

2014 ◽  
Vol 15 (2) ◽  
pp. 757-762 ◽  
Author(s):  
Safia Ali Al-Attas ◽  
Suzan Seif Ibrahim ◽  
Hala Abbas Amer ◽  
Zeinab El-Said Darwish ◽  
Mona Hassan Hassan
Keyword(s):  
Saudi Arabia ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant ◽  
Mucosal Lesions

PD.221 Viral DNA in potentially malignant andmalignant oral mucosal lesions

2005 ◽  
Vol 1 (1) ◽  
pp. 134
Author(s):  
A. Faden ◽  
D. Moles ◽  
C.G. Teo ◽  
S.R. Porter
Keyword(s):  
Viral Dna ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant ◽  
Mucosal Lesions

Management of potentially malignant oral mucosal lesions by consultant UK oral and maxillofacial surgeons

1996 ◽  
Vol 34 (1) ◽  
pp. 28-36 ◽  
Author(s):  
J.J. Marley ◽  
C.G. Cowan ◽  
P.-J. Lamey ◽  
G.J. Linden ◽  
N.W. Johnson ◽  
...  
Keyword(s):  
Oral Mucosal Lesions ◽  
Potentially Malignant ◽  
Mucosal Lesions

Prevalence of oral cancer, oral potentially malignant disorders and other oral mucosal lesions in Cambodia

2016 ◽  
Vol 23 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Tepirou Chher ◽  
Sithan Hak ◽  
Thomas George Kallarakkal ◽  
Callum Durward ◽  
Anand Ramanathan ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Oral Potentially Malignant Disorders ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Mucosal Lesions

scholarly journals Presence of Candida albicans in potentially malignant oral mucosal lesions

2004 ◽  
Vol 12 (1) ◽  
pp. 51-54 ◽  
Author(s):  
Nada Vuckovic ◽  
Marija Bokor-Bratic ◽  
Dejan Vuckovic ◽  
Ivana Picuric
Keyword(s):  
Candida Albicans ◽  
Lichen Planus ◽  
Oral Mucosa ◽  
Viral Infections ◽  
Oral Candidiasis ◽  
Candida Infection ◽  
Lower Lip ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant ◽  
Mucosal Lesions

Recently, an interest in the study of oral candidiasis has markedly increased mainly because of its association with viral infections due to human immunodeficiency, but also because of its relation with potentially malignant lesions of oral mucosa. These lesions belong to the wide group of leukoplakia. Leukoplakia is a clinical term used to describe a range of nonspecific white lesions, whose appearance does not generally correlate well with histopathologic changes; therefore, biopsy should be performed in all cases to determine which are precancerous or potentially malignant ones. In order to study the association of Candida albicans and the types of mucosal lesions, we took 30 consecutive biopsies of oral mucosa and the smears for microbiologic examination from the changed surface of mucosa and from the rest of oral cavity. The study group consisted of 30 patients, 21 women and 9 men, with the average age of 50.23 years (range, 25-77 years). In 6 cases Candida was diagnosed in mucosal biopsy. In the smear from the lesion, it was present in 3 cases, and 2 cases were found in the smear from an unchanged oral mucosa. In 9/30 cases (30%) Candida was positive regardless of the smear area or mode of diagnosis. The most common lesion is leukoplakia, diagnosed in 12/30 cases (40%), in 6 female and 6 male patients. The average age of those patients was 52.42 years. The lesions were located as follows: cheek mucosa - 5 cases; gingival mucosa - 2; lower lip - 2; floor of the mouth - 2; soft palate - 1; Candida was present in 3/12 cases. The lesion with the second highest incidence is lichen planus (9 cases), with positive Candida infection in 4/9 (44.44%). Epithelial dysplasia, although diagnosed in a very small number of cases (1/30 or 3.3%) with leukoplakia, was associated with a Candida infection. Generally, Candida is present in potentially malignant oral mucosal lesions (in 3/12 or 25% of leukoplakia cases, in 4/9 or 44.44% of lichen planus cases, and 1/1 squamous papilloma), with an increasing incidence in lesions with serious dysplastic epithelial changes.

scholarly journals Mouth Self-Examination (MSE) As a Screening Tool for Oral Potentially Malignant Disorders Among a High-Risk Indigenous Population With a Low Socioeconomic Status

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 48s-48s
Author(s):  
I.A. Razak ◽  
W.M.N. Ghani ◽  
J.G. Doss ◽  
A. Ramanathan ◽  
Z. Tahir ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Screening Tool ◽  
Oral Potentially Malignant Disorders ◽  
Betel Quid Chewing ◽  
Oral Mucosal Lesions ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Mucosal Lesions ◽  
Self Examination

Background: Oral cancer can be preceded by a group of conditions termed oral potentially malignant disorders (OPMDs). Oral cancers are associated with a 5-year survival of less than 50%, largely attributed to diagnoses at advanced stages. As pain associated with oral cancer manifests only at late stages, delay in detection often occurs. Screening has been found to aid in detection at an early stage, however it is only feasible if targeted toward high risk individuals. Mouth self-examination (MSE) is a relatively quick, inexpensive and simple to perform method of screening. Aim: To evaluate the efficacy of MSE as a screening tool for detection of oral mucosal lesions and OPMDs in a high risk indigenous population with a high prevalence of tobacco and betel quid chewing habit. Methods: Two villages were selected as the sampling frame based on prevalence of tobacco and betel quid chewing habit. Respondents were asked to check their mouth for presence of lesion or abnormalities. Education on oral cancer, including MSE was provided. Subsequently, respondents were asked to perform MSE. Finally, a comprehensive oral examination (COE) was done by a specialist and the presence of oral mucosal lesions was recorded. Results: Almost 64.5% of respondents exhibited high levels of difficulty and low mucosal visualization and retracting ability, whereas 3.0% demonstrated high attention level when performing MSE. Prevalence of oral mucosal lesions was 59.0%, whereas the prevalence of oral potentially malignant disorders (OPMDs) was 9.0%. Detection of oral lesions by respondents using MSE was lower than detection by the gold standard. Sensitivity and specificity of MSE for detection of all types of lesions were 8.6% and 95.0% respectively. When analyzing each lesion type separately, MSE was found to be most sensitive in detection of swellings (10.0%), and most specific in identifying red lesions (100.0%). For detection of OPMDs, MSE yielded a high specificity of 98.9%, with an accuracy rate of 91.8%. Conclusion: MSE is a potentially good screening tool for OPMDs and oral cancer; however, awareness level of the public on oral cancer and its associated signs and symptoms needs to be improved.

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