scholarly journals Increased risk of mortality and loss to follow-up among HIV-positive patients with oropharyngeal candidiasis and malnutrition before antiretroviral therapy initiation: a retrospective analysis from a large urban cohort in Johannesburg, South Africa

2012 ◽  
Vol 113 (3) ◽  
pp. 362-372 ◽  
Author(s):  
Denise Evans ◽  
Mhairi Maskew ◽  
Ian Sanne
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Retrospective Analysis ◽  
Hiv Positive ◽  
Oropharyngeal Candidiasis ◽  
Loss To Follow Up ◽  
Therapy Initiation ◽  
Risk Of Mortality ◽  
Increased Risk

Patient Loss to Follow-Up Before Antiretroviral Therapy Initiation in Rural Mozambique

2014 ◽  
Vol 19 (4) ◽  
pp. 666-678 ◽  
Author(s):  
Monica da Silva ◽  
Meridith Blevins ◽  
C. William Wester ◽  
José Manjolo ◽  
Eurico José ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Loss To Follow Up ◽  
Therapy Initiation

scholarly journals The HIV care cascade for adolescents initiated on antiretroviral therapy in a health district of South Africa: a retrospective cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Roxanna Haghighat ◽  
Elona Toska ◽  
Nontuthuzelo Bungane ◽  
Lucie Cluver
Keyword(s):  
South Africa ◽  
Viral Load ◽  
Antiretroviral Therapy ◽  
Viral Suppression ◽  
Hiv Care ◽  
Loss To Follow Up ◽  
Hiv Care Cascade ◽  
Care Cascade ◽  
Clinical Records

Abstract Background Little evidence exists to comprehensively estimate adolescent viral suppression after initiation on antiretroviral therapy in sub-Saharan Africa. This study examines adolescent progression along the HIV care cascade to viral suppression for adolescents initiated on antiretroviral therapy in South Africa. Methods All adolescents ever initiated on antiretroviral therapy (n=1080) by 2015 in a health district of the Eastern Cape, South Africa, were interviewed in 2014–2015. Clinical records were extracted from 52 healthcare facilities through January 2018 (including records in multiple facilities). Mortality and loss to follow-up rates were corrected for transfers. Predictors of progression through the HIV care cascade were tested using sequential multivariable logistic regressions. Predicted probabilities for the effects of significant predictors were estimated by sex and mode of infection. Results Corrected mortality and loss to follow-up rates were 3.3 and 16.9%, respectively. Among adolescents with clinical records, 92.3% had ≥1 viral load, but only 51.1% of viral loads were from the past 12 months. Adolescents on ART for ≥2 years (AOR 3.42 [95%CI 2.14–5.47], p< 0.001) and who experienced decentralised care (AOR 1.39 [95%CI 1.06–1.83], p=0.018) were more likely to have a recent viral load. The average effect of decentralised care on recent viral load was greater for female (AOR 2.39 [95%CI 1.29–4.43], p=0.006) and sexually infected adolescents (AOR 3.48 [95%CI 1.04–11.65], p=0.043). Of the total cohort, 47.5% were recorded as fully virally suppressed at most recent test. Only 23.2% were recorded as fully virally suppressed within the past 12 months. Younger adolescents (AOR 1.39 [95%CI 1.06–1.82], p=0.017) and those on ART for ≥2 years (AOR 1.70 [95%CI 1.12–2.58], p=0.013) were more likely to be fully viral suppressed. Conclusions Viral load recording and viral suppression rates remain low for ART-initiated adolescents in South Africa. Improved outcomes for this population require stronger engagement in care and viral load monitoring.

scholarly journals Loss to follow-up correction increased mortality estimates in HIV–positive people on antiretroviral therapy in Mozambique

2020 ◽  
Vol 128 ◽  
pp. 83-92
Author(s):  
Nanina Anderegg ◽  
Jonas Hector ◽  
Laura F. Jefferys ◽  
Juan Burgos-Soto ◽  
Michael A. Hobbins ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Hiv Positive ◽  
Loss To Follow Up ◽  
Mortality Estimates

scholarly journals CD4 count at antiretroviral therapy initiation and the risk of loss to follow-up: results from a multicentre cohort study

2015 ◽  
Vol 70 (6) ◽  
pp. 549-555 ◽  
Author(s):  
Anna Grimsrud ◽  
Morna Cornell ◽  
Michael Schomaker ◽  
Matthew P Fox ◽  
Catherine Orrell ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antiretroviral Therapy ◽  
Cd4 Count ◽  
Loss To Follow Up ◽  
Therapy Initiation ◽  
Multicentre Cohort Study ◽  
Multicentre Cohort
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