Acute intake of phenolic-rich juice improves antioxidant status in healthy subjects

2006 ◽  
Vol 26 (7) ◽  
pp. 330-339 ◽  
Author(s):  
Javier García-Alonso ◽  
Gaspar Ros ◽  
M. Luisa Vidal-Guevara ◽  
M. Jesús Periago
Keyword(s):  
Healthy Subjects ◽  
Antioxidant Status ◽  
Acute Intake

Riceberry rice beverage decreases postprandial glycemic response, inflammatory markers and antioxidant status induced by a high carbohydrate and moderate fat meal in overweight and obese men

2022 ◽  
Author(s):  
Tanisa anuyahong ◽  
Charoonsri Chusak ◽  
Sirichai Adisakwattana
Keyword(s):  
Clinical Studies ◽  
Inflammatory Markers ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Current Work ◽  
Glycemic Response ◽  
High Carbohydrate ◽  
Beneficial Role ◽  
Fat Meal

Recent clinical studies support the beneficial role of riceberry rice and its food products on controlling glycemic response in healthy subjects. The aim of the current work was to determine...

Short-term supplementation with flavanol-rich cocoa improves lipid profile, antioxidant status and positively influences the AA/EPA ratio in healthy subjects

2018 ◽  
Vol 61 ◽  
pp. 33-39 ◽  
Author(s):  
Sergio Davinelli ◽  
Graziamaria Corbi ◽  
Armando Zarrelli ◽  
Mariachiara Arisi ◽  
Piergiacomo Calzavara-Pinton ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Short Term

scholarly journals Polyphenol Bioavailability and Plasma Antiradical Capacity in Healthy Subjects after Acute Intake of Pigmented Rice: A Crossover Randomized Controlled Clinical Trial

2020 ◽  
Vol 9 (10) ◽  
pp. 3209
Author(s):  
Sara Vitalini ◽  
Andrea Sardella ◽  
Daniela Fracassetti ◽  
Rita Secli ◽  
Antonio Tirelli ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Healthy Subjects ◽  
Controlled Clinical Trial ◽  
Rice Cultivars ◽  
Randomized Controlled Clinical Trial ◽  
Black Rice ◽  
Antioxidant Power ◽  
Pigmented Rice ◽  
Randomized Controlled ◽  
Acute Intake

Health-promoting effects of plant foods have been emphasized in the last few decades and ascribed to the bioactive phytochemicals present therein—in particular, phenylpropanoids. The latter have been investigated for a number of preclinical biological activities, including their antioxidant power. Due to the paucity of human studies, in this randomized intervention trial, we investigated whether the acute intake of pigmented rice could increase the plasma bioactive levels and antiradical power in twenty healthy subjects. A crossover randomized controlled clinical trial was conducted on 19 volunteers. Artemide and Venere black rice cultivars were tested, while brown rice Carnaroli was used as a control. Each patient received randomly one serving (100 g) of rice on three different experimental days, separated by a 7-day washout period. After baseline blood withdrawal, time-course changes of plasma polyphenols, flavonoids and radical-scavenging capacity were determined at 30, 60, 120 and 180 min post rice intake. Compared to Carnaroli rice, the two black rice cultivars significantly increased the plasma levels of polyphenols and flavonoids at 60 and 120 min and, correspondingly, the plasma antiradical power at 60 min after consumption. Pigmented rice consumption can contribute to diet-related health benefits in humans.

scholarly journals Postprandial Glycemia, Insulinemia, and Antioxidant Status in Healthy Subjects after Ingestion of Bread made from Anthocyanin-Rich Riceberry Rice

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 782 ◽  
Author(s):  
Charoonsri Chusak ◽  
Porntip Pasukamonset ◽  
Praew Chantarasinlapin ◽  
Sirichai Adisakwattana
Keyword(s):  
Glucose Concentration ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Thiol Group ◽  
Wheat Bread ◽  
Blood Collection ◽  
Glycemic Response ◽  
Gluten Free ◽  
Postprandial Plasma Glucose ◽  
Reducing Ability

Riceberry rice, a gluten-free grain, contains many nutrient components, including carbohydrates, proteins, certain fatty acids, and micronutrients, as well as bioactive non-nutrient compounds, such as polyphenolic compounds. This study aimed to evaluate the effect of bread made from anthocyanin-rich Riceberry rice on the postprandial glycemic response, glucagon-like peptide-1 (GLP-1), antioxidant status, and subjective ratings of appetite. In the crossover design, 16 healthy participants (six men and 10 women) completed four sessions involving blood collection in the fasting state and at 30, 60, 90, 120, 150, and 180 min after food consumption (50 g of available carbohydrate) in a randomized order: 1) glucose solution, 2) wheat bread (WB), 3) Riceberry rice bread (RRB), and 4) Hom Mali bread (HMB). Consumption of RRB resulted in significantly lower postprandial plasma glucose concentration at 30 and 60 min when compared to HMB. No difference in postprandial glucose concentration between RRB and WB was observed. In addition, postprandial plasma insulin showed a significant decrease in the group which received RRB at 15 and 60 min, as compared to HMB. In comparison with 50 g of glucose, as a reference, the glycemic index (GI) of RRB, WB, and HMB was 69.3 ± 4.4, 77.8 ± 4.6, and 130.6 ± 7.9, respectively. Interestingly, the ferric-reducing ability of plasma (FRAP) level was shown to significantly increase after consumption of RRB. In the meantime, a significant decrease in the postprandial FRAP level was also observed following an intake of WB and HMB. All breads caused increases in the postprandial plasma protein thiol group and had similar effects on hunger, fullness, desire to eat, and satiety ratings. However, consumption of RBB, WB, and HMB did not change plasma GLP-1 and malondialdehyde (MDA) levels when compared to the baseline. The findings suggest that anthocyanin-rich Riceberry rice can be a natural ingredient for gluten-free bread which reduced glycemic response together with improvement of antioxidant status in healthy subjects.

Oxidative stress in Vitiligo patients and administration of Munzij and Mushil therapy, a poly herbal Unani formulation – hospital-based study

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Towseef Amin Rafeeqi ◽  
Farhat Jabeen ◽  
M A Waheed ◽  
Gulam Mohammed Husain ◽  
Alokananda Chakraborthy
Keyword(s):  
Oxidative Stress ◽  
Healthy Subjects ◽  
Skin Disorder ◽  
Antioxidant Status ◽  
The Body ◽  
Oxygen Species ◽  
Statistical Significant Difference ◽  
Significant Difference ◽  
Gpx Activity

AbstractBackgroundVitiligo, a skin disorder is viewed as a multifactorial process with major role of reactive oxygen species in concert to destroy or incapacitate melanocytes. In Unani system of medicine the treatment of Bars (Vitiligo) starts with removal of harmful materials from the body with Munzij and Mushil (MM), a poly herbal Unani formulation.MethodsHerein, oxidative stress related parameters as MDA, SOD, GPx and CAT have been estimated in the 21 clinically diagnosed Vitiligo in-patients and subsequently these parameters were evaluated during and after administration of MM therapy and compared with 21 healthy subjects.ResultsThere was significant difference in the parameters viz., SOD (p<0.001) and CAT (p<0.005) activity at the baseline with no statistical significant difference in MDA and GPx activity among Vitiligo subjects and controls. After MM therapy there was no statistical significant difference among the values of these parameters in Vitiligo subjects.ConclusionsThe results suggest that there is imbalance in the oxidant-antioxidant status of Vitiligo subjects and the MM therapy is not found to significantly change the levels of oxidative stress related parameters.

Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomized crossover trial

2021 ◽  
pp. 1-29
Author(s):  
Marina V. Geraldi ◽  
Cínthia B. B. Cazarin ◽  
Marcelo Cristianini ◽  
Ana C. Vasques ◽  
Bruno Geloneze ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Metabolic Diseases ◽  
Area Under The Curve ◽  
C Peptide ◽  
Test Product ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Carbohydrate Meal

Abstract Jabuticaba is a Brazilian berry rich in polyphenols, which may exert beneficial effects on metabolic diseases. This randomized crossover study aimed to determine the effects of jabuticaba juice (250 ml in a portion) on postprandial response. Sixteen healthy subjects (11 women; 5 men; 28.4 ± 3.8 years old; body mass index (BMI) 21.7 ± 2.3 kg m−2) consumed two test products after fasting overnight in a randomized controlled crossover design. Each test product portion had a similar composition of sugar components: 250 mL water with glucose, fructose, colored with artificial non-caloric food colorings (placebo); and 250 mL of jabuticaba juice. Beverages were administered immediately before a carbohydrate meal. Blood samples were collected at 0, 15, 30, 45, 60, 90, and 120 min after each test product to analyze the concentrations of glucose, insulin, C-peptide, antioxidant capacity, plasma glucagon-like peptide-1 (GLP-1), and appetite sensations. Compared to the placebo, the intake of jabuticaba juice resulted in a higher GLP-1 response as the area under the curve (AUC) and peaking at 60 min. Jabuticaba juice also resulted in higher antioxidant capacity. Postprandial glucose, insulin, C-peptide levels, and appetite sensations were not significantly different between tests. In conclusion, 250 mL of jabuticaba juice before a carbohydrate meal was able to improve the antioxidant status and GLP-1 concentrations in healthy subjects.

scholarly journals An acute intake of plant stanol esters alters immune-related pathways in the jejunum of healthy volunteers

2015 ◽  
Vol 113 (5) ◽  
pp. 794-802 ◽  
Author(s):  
Els De Smet ◽  
Ronald P. Mensink ◽  
Mark V. Boekschoten ◽  
Rogier de Ridder ◽  
Wilfred T. V. Germeraad ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Healthy Subjects ◽  
Expression Profiles ◽  
Papilla Of Vater ◽  
Sterol Metabolism ◽  
Plant Stanol ◽  
Cluster Of Differentiation ◽  
Plant Stanol Esters ◽  
Stanol Ester ◽  
Acute Intake

Plant sterols and stanols inhibit intestinal cholesterol absorption and consequently lower serum LDL-cholesterol (LDL-C) concentrations. The underlying mechanisms are not yet known. In vitro and animal studies have suggested that changes in intestinal sterol metabolism are attributed to the LDL-C-lowering effects of plant stanol esters. However, similar studies in human subjects are lacking. Therefore, we examined the effects of an acute intake of plant stanol esters on gene expression profiles of the upper small intestine in healthy volunteers. In a double-blind cross-over design, fourteen healthy subjects (eight female and six male; age 21–55 years), with a BMI ranging from 21 to 29 kg/m2, received in random order a shake with or without plant stanol esters (4 g). At 5 h after consumption of the shake, biopsies were taken from the duodenum (around the papilla of Vater) and from the jejunum (20 cm distal from the papilla of Vater). Microarray analysis showed that the expression profiles of genes involved in sterol metabolism were not altered. Surprisingly, the pathways involved in T-cell functions were down-regulated in the jejunum. Furthermore, immunohistochemical analysis showed that the number of CD3 (cluster of differentiation number 3), CD4 (cluster of differentiation number 4) and Foxp3+ (forkhead box P3-positive) cells was reduced in the plant stanol ester condition compared with the control condition, which is in line with the microarray data. The physiological and functional consequences of the plant stanol ester-induced reduction of intestinal T-cell-based immune activity in healthy subjects deserve further investigation.

scholarly journals Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects

2005 ◽  
Vol 94 (5) ◽  
pp. 639-642 ◽  
Author(s):  
Timur Anlasik ◽  
Helmut Sies ◽  
Helen R. Griffiths ◽  
Patrizia Mecocci ◽  
Wilhelm Stahl ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Fruits And Vegetables ◽  
Community Dwelling ◽  
Protein Carbonyls ◽  
Elderly Subjects ◽  
Age And Gender ◽  
Age Related ◽  
And Gender

Previous studies indicate that regular consumption of a diet rich in fruits and vegetables is associated with a lower risk for age-related diseases. The aim of the present study was to evaluate whether the often-reported age-related decrease of plasma antioxidants in man depends on differences in dietary intake or on other age- and gender-related factors. In this observational case-control study, thirty-nine community-dwelling healthy subjects aged 65 years and older consuming high intakes of fruits and vegetables daily (HI) and forty-eight healthy subjects aged 65 and older consuming low intakes of fruit and vegetables daily (LI) were enrolled. Plasma levels of retinol, tocopherols, carotenoids and malondialdehyde (MDA) as well as content of protein carbonyls in Ig G were measured. Plasma levels of retinol, tocopherols and carotenoids were significantly higher in group HI than in group LI subjects independent of age and gender. MDA levels were inversely correlated with vitamin A and α-carotene. Protein carbonyls were inversely correlated with γ-tocopherol. In the elderly, a higher daily intake of fruits and vegetables is associated with an improved antioxidant status in comparison to subjects consuming diets poor in fruits and vegetables. Modification of nutritional habits among other lifestyle changes should be encouraged to lower prevalence of disease risk factors in later life.

Sign in / Sign up

Export Citation Format

Share Document