Polymorphisms in Vitamin D receptor and Parathyroid Hormone Genes in the Development and Progression of Obstructive Sleep Apnea in Asian Indians.

Nutrition ◽  
2021 ◽  
pp. 111237
Author(s):  
Surya Prakash Bhatt ◽  
Randeep Guleria
Respiration ◽  
2013 ◽  
Vol 86 (4) ◽  
pp. 295-301 ◽  
Author(s):  
Antonia Barceló ◽  
Cristina Esquinas ◽  
Javier Piérola ◽  
Mónica De la Peña ◽  
Manuel Sánchez-de-la-Torre ◽  
...  

Author(s):  
Daniela Krasimirova ◽  
Radoslav Bilyukov ◽  
Ventsislava Pencheva ◽  
Daniela Petrova ◽  
Tzanko Mondeshki ◽  
...  

Endocrine ◽  
2013 ◽  
Vol 45 (2) ◽  
pp. 311-318 ◽  
Author(s):  
Ersin Sukru Erden ◽  
Sebahat Genc ◽  
Sedat Motor ◽  
Ihsan Ustun ◽  
Kemal Turker Ulutas ◽  
...  

2019 ◽  
Vol 80 (5-6) ◽  
pp. 319-323 ◽  
Author(s):  
Zeqin Fan ◽  
Bing Cao ◽  
Hong Long ◽  
Lijie Feng ◽  
Qianjun Li ◽  
...  

Author(s):  
Banu Musaffa Salepçi ◽  
Benan Caglayan ◽  
Elif Torun Parmaksiz ◽  
Nesrin Kiral ◽  
Ali Fidan ◽  
...  

2011 ◽  
Vol 30 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Bharat Bhushan ◽  
Randeep Guleria ◽  
Anoop Misra ◽  
Kalpana Luthra ◽  
Guresh Kumar

Background:Obstructive sleep apnea (OSA) is prevalent in 7.5% in urban Asian Indians.Peroxisome proliferator activated receptor gamma2 (PPARγ2)has been implicated in adipocyte differentiation.Neuropeptide Y (NPY)is also considered as a candidate gene for excess body fat accumulation. The association ofPPARγ2 (Pro12Ala)andNPY (Leu7Pro)gene polymorphisms with OSA has not been studied in Asian Indians.Objective:To study the distribution ofPPARγ2 (Pro12Ala)andNPY (Leu7Pro)polymorphism in Asian Indians with and without OSA.Methods and results:This study was carried out in 252 obese subjects [(body mass index (BMI > 25 kg/m2)]; 142 with OSA and 110 without OSA. Measurements included anthropometric and biochemical parameters (fasting blood glucose, lipid profile, various circumferences and skin-fold thicknesses).PPARγ2 (Pro12Ala) and NPY (Leu7Pro) genepolymorphisms were studied in all subjects. The frequency of the variantallele (Ala12) of PPARγ2 genewas significantly higher in subjects with OSA (14.4%) when compared with subjects without OSA (5.5%; χ2= 9.7;p= 0.001). The distribution of the variantallele (Pro7)ofNPY genewas comparable in subjects with OSA (3.5%) and without OSA (3.6%; χ2= 0.001,p= 0.94).Conclusion:This study reveals a significantly higher frequency ofPPARγ2 (Ala12) allelein obese Asian Indians with OSA when compared to obese Asian Indians without OSA.


Author(s):  
Hülya Albayrak ◽  
Nevin Fazlıoğlu ◽  
Bahadır Batar ◽  
Mehmet Emin Yanık ◽  
Mustafa Oran ◽  
...  

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