scholarly journals Postprandial glucose and insulin response to a high-fiber muffin top containing resistant starch type 4 in healthy adults: a double-blind, randomized, controlled trial

Nutrition ◽  
2018 ◽  
Vol 53 ◽  
pp. 59-63 ◽  
Author(s):  
Maria L. Stewart ◽  
J. Paul Zimmer
Keyword(s):  
Randomized Controlled Trial ◽  
Resistant Starch ◽  
Controlled Trial ◽  
Insulin Response ◽  
Postprandial Glucose ◽  
Healthy Adults ◽  
Double Blind ◽  
High Fiber ◽  
Randomized Controlled

scholarly journals Nutritional Bar with Potato-Based Resistant Starch Attenuated Post-Prandial Glucose and Insulin Response in Healthy Adults

Foods ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1679
Author(s):  
Vishnupriya Gourineni ◽  
Maria L. Stewart ◽  
Meredith L. Wilcox ◽  
Kevin C. Maki
Keyword(s):  
Resistant Starch ◽  
Area Under Curve ◽  
Insulin Response ◽  
Healthy Adults ◽  
Double Blind ◽  
Total Dietary Fiber ◽  
High Fiber ◽  
Naturally Occurring ◽  
Capillary Glucose ◽  
Physiological Benefits

Resistant starch is a non-digestible starch fraction and is classified as fiber. Beyond naturally occurring fiber sources, starches can be modified to resist digestion, increase their fiber content and provide physiological benefits. The current study examined acute postprandial glycemic responses of VERSAFIBE™ 1490 resistant starch type-4, containing 90% total dietary fiber (TDF, AOAC (Association of Official Analytical Collaboration International) 991.43 method). In a double-blind, randomized, placebo-controlled, cross-over study, healthy adults (n = 38) consumed a nutritional bar containing either control (2 g), medium (21 g) or high (30 g) fiber. The test bars were matched with control for available carbohydrates, fat and protein. Venous glucose, insulin, and capillary glucose were measured. Mean ± SEM capillary glucose incremental area-under-curve (iAUC0)-120 min in min*mmol/L was lower (p < 0.005) for both fiber bars (136.2 ± 9.2 and 137.0 ± 10.4 for the medium and high fiber bars, respectively) compared to the control bar (174.9 ± 13.5). Mean venous insulin iAUC0-120 min in min*pmol/L was also lower for medium (8096.3 ± 894.5) and high fiber (7533.8 ± 932.9) bars, respectively, compared to the control bar (11871.6 ± 1123.9, p < 0.001). Peak capillary glucose and venous insulin concentrations were also significantly reduced (p < 0.001) after consumption of both fiber bars compared to the control bar. The results of this study suggest that nutritional bars containing potato based RS4 fiber reduced post-consumption glycemic and insulinemic responses when consumed by generally healthy adults.

Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial

2001 ◽  
Vol 26 (1) ◽  
pp. 67-71 ◽  
Author(s):  
S. A. Ahmadi-Abhari ◽  
S. Akhondzadeh ◽  
S. M. Assadi ◽  
O. L. Shabestari ◽  
Z. M. Farzanehgan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Side Effects ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled
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