Branched-chain amino acid supplementation and exercise-induced muscle damage in exercise recovery: A meta-analysis of randomized clinical trials

Nutrition ◽  
2017 ◽  
Vol 42 ◽  
pp. 30-36 ◽  
Author(s):  
Mohammad Hossein Rahimi ◽  
Sakineh Shab-Bidar ◽  
Mehdi Mollahosseini ◽  
Kurosh Djafarian
Keyword(s):  
Clinical Trials ◽  
Amino Acid ◽  
Muscle Damage ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Amino Acid Supplementation ◽  
Exercise Recovery ◽  
Branched Chain Amino Acid ◽  
Branched Chain ◽  
Exercise Induced

Effect of branched-Chain Amino Acid Supplementation on Muscle Soreness following Exercise: A Meta-Analysis

2019 ◽  
Vol 89 (5-6) ◽  
pp. 348-356 ◽  
Author(s):  
Michael V. Fedewa ◽  
Steven O. Spencer ◽  
Tyler D. Williams ◽  
Zachery E. Becker ◽  
Collin A. Fuqua
Keyword(s):  
Amino Acid ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Delayed Onset Muscle Soreness ◽  
Control Group ◽  
Acute Bout ◽  
Delayed Onset ◽  
Branched Chain Amino Acid ◽  
Branched Chain ◽  
Exercise Induced

Abstract. Delayed onset muscle soreness (DOMS) is a symptom of exercise-induced muscle damage that occurs following exercise. Previous research has indicated that branched-chain amino acid (BCAA) supplementation may attenuate exercise-induced muscle damage that causes delayed onset muscle soreness, however the results are inconsistent. The primary aim of this study was to examine the previous literature assessing the effect of BCAA supplementation on DOMS following an acute bout of exercise in adults. This review was conducted in accordance with PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-analyses), and identified peer-reviewed articles comparing a BCAA supplement to a placebo non-BCAA supplement following an acute bout of exercise. An electronic search of three databases (EbscoHost, Web of Science, and SPORTDiscus) yielded 42 articles after duplicates were removed. All studies included in the current analyis were: 1) peer-reviewed publications; 2) available in English; 3) utilized a random control design that compared a BCAA group to a placebo control group following exercise; 4) and assessed soreness of muscle tissue during recovery. DOMS was assessed in 61 participants following ingestion of a BCAA supplement over the course of these interventions. The cumulative results of 37 effects gathered from 8 studies published between 2007 and 2017 indicated that BCAA supplementation reduced DOMS following exercise training (ES = 0.7286, 95% CI: 0.5017 to 0.9555, p < 0.001). A large decrease in DOMS occurs following BCAA supplementation after exercise compared to a placebo supplement.

scholarly journals Acute And Chronic Effects Of Branched-chain Amino Acid Supplementation: A Systematic Review And Meta-analysis

2020 ◽  
Vol 52 (7S) ◽  
pp. 457-457
Author(s):  
Lauren M. Colenso-Semple ◽  
Robert W. Morton ◽  
Matthew Fliss ◽  
Mirette Mounir ◽  
Mina Mladenovic ◽  
...  
Keyword(s):  
Systematic Review ◽  
Amino Acid ◽  
Meta Analysis ◽  
Amino Acid Supplementation ◽  
Acid Supplementation ◽  
Branched Chain Amino Acid ◽  
Chronic Effects ◽  
Branched Chain ◽  
Acute And Chronic Effects

scholarly journals The effects of acute branched-chain amino acid supplementation on recovery from a single bout of hypertrophy exercise in resistance-trained athletes

2017 ◽  
Vol 42 (6) ◽  
pp. 630-636 ◽  
Author(s):  
Mark Waldron ◽  
Kieran Whelan ◽  
Owen Jeffries ◽  
Dean Burt ◽  
Louis Howe ◽  
...  
Keyword(s):  
Amino Acid ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Training Session ◽  
Isometric Strength ◽  
Dietary Control ◽  
Amino Acid Supplementation ◽  
Double Blind ◽  
Branched Chain Amino Acid ◽  
Branched Chain

This study investigated the effects of acute branched-chain amino acid (BCAA) supplementation on recovery from exercise-induced muscle damage among experienced resistance-trained athletes. In a double-blind matched-pairs design, 16 resistance-trained participants, routinely performing hypertrophy training, were randomly assigned to a BCAA (n = 8) or placebo (n = 8) group. The BCAAs were administered at a dosage of 0.087 g/kg body mass, with a 2:1:1 ratio of leucine, isoleucine, and valine. The participants performed 6 sets of 10 full-squats at 70% 1-repetition maximum to induce muscle damage. All participants were diet-controlled across the study. Creatine kinase, peak isometric knee-extensor force, perceived muscle soreness, and countermovement jump (CMJ) height were measured immediately before (baseline) and at 1 h, 24 h, and 48 h postexercise. There were large to very large time effects for all measurements between baseline and 24–48 h. Between-group comparisons, expressed as a percentage of baseline, revealed differences in isometric strength at 24-h (placebo ∼87% vs. BCAA ∼92%; moderate, likely), CMJ at 24 h (placebo ∼93% vs. BCAA ∼96%; small, likely), and muscle soreness at both 24 h (placebo ∼685% vs. BCAA ∼531%; small, likely) and 48 h (placebo ∼468% vs. BCAA ∼350%; small, likely). Acute supplementation of BCAAs (0.087 g/kg) increased the rate of recovery in isometric strength, CMJ height, and perceived muscle soreness compared with placebo after a hypertrophy-based training session among diet-controlled, resistance-trained athletes. These findings question the need for longer BCAA loading phases and highlight the importance of dietary control in studies of this type.

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