A meal replacement regimen improves blood glucose levels in prediabetic healthy individuals with impaired fasting glucose

Nutrition ◽  
2014 ◽  
Vol 30 (11-12) ◽  
pp. 1306-1309 ◽  
Author(s):  
Daniel König ◽  
Sadaf Kookhan ◽  
Denise Schaffner ◽  
Peter Deibert ◽  
Aloys Berg
Keyword(s):  
Blood Glucose ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Healthy Individuals ◽  
Meal Replacement ◽  
Glucose Levels ◽  
Blood Glucose Levels

Effect of consumption of a carob pod inositol-enriched beverage on insulin sensitivity and inflammation in middle-aged prediabetic subjects

2016 ◽  
Vol 7 (10) ◽  
pp. 4379-4387 ◽  
Author(s):  
Celia Bañuls ◽  
Susana Rovira-Llopis ◽  
Sandra López-Doménech ◽  
Silvia Veses ◽  
Víctor M. Víctor ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Insulin Sensitivity ◽  
Body Mass ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Middle Aged ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Carob Pod

This study assessed the effects of an inositol-enriched beverage (IEB) on blood glucose levels and inflammation status in subjects with an impaired fasting glucose (IFG) state according to body mass index (BMI).

scholarly journals Acute Effect of Height-Adjustable Workstations on Blood Glucose Levels in Women with Impaired Fasting Glucose Levels While Working: A Pilot Study

2021 ◽  
Vol 6 (4) ◽  
Author(s):  
Amanda R. Bonikowske ◽  
Katie C. Carpenter ◽  
Steven D. Stovitz ◽  
Dipankar Bandyopadhyay ◽  
Mark A. Pereira ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Pilot Study ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Acute Effect ◽  
Glucose Levels ◽  
Blood Glucose Levels

scholarly journals Association of a Self-Paid Medically Supervised Weight Management Program with Reversal of Obesity-Associated Impaired Fasting Glucose

2021 ◽  
Vol 11 (2) ◽  
pp. 386-394
Author(s):  
Vijaya Surampudi ◽  
Xinkai Zhou ◽  
Chi-Hong Tseng ◽  
David Heber ◽  
Zhaoping Li
Keyword(s):  
Weight Loss ◽  
Blood Glucose ◽  
Retrospective Analysis ◽  
Weight Management ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Management Program ◽  
Weight Management Program ◽  
Glucose Levels

Aims: The progression of prediabetes to T2DM can be delayed through diet modification and weight management. However, the intensive lifestyle program is often not covered by medical insurance. This retrospective analysis evaluates the association of a patient self-paid weight management program on an improvement of blood sugar in overweight and obese patients with impaired fasting glucose (IFG). Methods: The medical records of 4634 patients who participated in the self-pay UCLA Weight Management Program were reviewed and 2572 patients met the criteria for this retrospective analysis to examine whether this program was associated with the reversal of IFG over 3 months among 1396 patients with normal fasting glucose (NFG) and 1176 with IFG. Results: The patients with IFG lost comparable amounts of weight (10.5 ± 1.3 kg) at three months, as did the subjects with NFG (10.1 ± 1.3 kg). Fasting blood glucose in the IFG group decreased from 108.49 ± 6.4 to 101.8 ± 9.41 mg/dL (p < 0.0001) after three months. There were also significant reductions in triglycerides, and both systolic and diastolic blood pressure in both groups in association with weight loss. Conclusion: Our medically supervised self-pay multidisciplinary weight management program was associated with reduced fasting blood glucose levels in patients with IFG over three months with comparable weight loss to patients with NFG.

scholarly journals Hypoglycemic Activity of Okra (Abelmoschus esculentus) in Participants with Impaired

2019 ◽  
Vol 7 (1) ◽  
pp. 626-635
Author(s):  
Czari Jo Lauren ADAP ◽  
CARLA RHOCEL T DIAZ ◽  
Paula Louise J. Victorino ◽  
Ma. Kristine HERNANDEZ MENDOZA ◽  
YANNA YVONNE CAAGBAY MACAYAN
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
Short Duration ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Abelmoschus Esculentus ◽  
Glucose Load ◽  
Experimental Phase ◽  
Control Phase ◽  
Glucose Levels

Introduction: Impaired fasting glucose (IFG) is characterized by a blood glucose level higher than normal but lower than that of diabetes level. Abelmoschus esculentus (okra) is an alternative hypoglycemic and antidiabetic plant due to its phytochemical constituents that regulate intestinal glucose absorption and prevents insulin resistance. This study determined the hypoglycemic activity of okra among IFG participants. Methodology: Subjects were random subjects with impaired fasting glucose results upon screening.  Quasi-experimental pre-test post-test was used where a standard glucose load was consumed in the control phase and powdered okra seed-peel mixed with the glucose load was consumed during the experimental phase. The blood sugar concentration was measured again every hour until three hours after consumption of the standard glucose load. In the experimental phase, the same group of participants was asked to consume 75 grams of glucose load with powdered okra peel that depends on their body weight (200 mg/kg of body mass). Fasting, 1 -hour, 2-hour and 3-hour glucose concentration were measured the same way it was done during the control phase. Results: Statistical analysis revealed that Abelmoschus esculentus has its hypoglycemic effect only during the first hour while data results for the 2nd and 3 rd hour are considered insignificant. The results proved that okra’s mechanism in lowering glucose levels is immediate yet of short duration. Discussion: Based on the data gathered, the researchers conclude that the powdered peel of Abelmoschus esculentus (okra) is effective in lowering the blood glucose levels of IFG individuals only during the first hour after the administration of oral glucose load. Abelmoschus esculentus may not be effective in lowering the blood glucose after the next hours due to the fact that its mechanism of action is immediate but of short duration. The researchers recommend future researches on the study of Abelmoschus esculentus using increased dosage of each participant and that the experiment should be performed at the same month.   Keywords: Abelmoschus esculentus, okra, impaired fasting glucose, diabetes, hypoglycaemia, insulin resistance

scholarly journals Glucose metabolism and incretins level in morbidly obese patients and in patients after biliopancreatic diversion performed for morbid obesity

2014 ◽  
Vol 11 (1) ◽  
pp. 24-31
Author(s):  
I I Dedov ◽  
G A Melnichenko ◽  
E A Troshina ◽  
N V Mazurina ◽  
N A Ogneva ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glucose Metabolism ◽  
Biliopancreatic Diversion ◽  
Plasma Insulin ◽  
Fasting Glucose ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Insulin Levels ◽  
Glucose Levels ◽  
Blood Glucose Levels

We’ve studied a carbohydrate metabolism in morbidly obese (MO) patients and the patients after bariatric surgery. The patients of the 1st group had BMI40 (n=22) and no history of diabetes mellitus. Patients after biliopancreatic diversion (BPD) performed for MO were included in the 2nd group (n=23). The 3rd group was a control group of normal weight healthy subjects (n=22). Blood glucose levels, insulin, GLP-1, GIP and glucagon during the OGTT (with 75 g of glucose) at 0, 30, 60 and 120 minutes were measured in all patients. In MO group fasting glucose levels were the highest. Impaired glucose metabolism was revealed in 68.2% of patients (n=10). Impaired fasting glucose (IFG) was diagnosed in 4 cases (18.2%), impaired glucose tolerance (IGT) in 11 patients (50%). In the BPD postprandial blood glucose levels (120 min) were lower if compared to the other groups. In 4 individuals (17.4%) we found postprandial hypoglycemia (2.8 mmol/l). Patients of the MO group had the highest fasting insulin levels and HOMA-IR (p0.001). The maximum of insulin concentration was seen on minute 30 of the OGTT in the 2nd and 3rd groups, and it was significantly higher in the post-bariatric patients (p=0.026). In MO group the maximum of the plasma insulin levels were on the 60th minute and were still elevated after 120 minutes. Fasting and stimulated (on the 30th minute) levels of GLP-1 were significantly higher after BPD (р=0.037 and p=0.022 at 0 and 30 min, respectively). Morbidly obese patients had higher fasting and stimulated GIP. Fasting glucagon concentrations were similar in the surgical and control groups, while the people with MO had higher initial levels of glucagon (p=0.013) and it was not suppressed during the OGTT (p=0.076). Glucose intolerance and insulin resistance incidence was higher in MO patients. Hyperglucagonemia, increased GIP and decreased GLP-1 levels are observed in MO patients. Stimulated plasma insulin and GLP-1 concentrations were significantly increased in patients who underwent BPD, and may cause postprandial hypoglycemia.

scholarly journals Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Alia Ali Muhammed ◽  
Azeem Taj ◽  
Muhammed Uthman Ahmed ◽  
Elsa Tabrez
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Impaired Fasting Glucose ◽  
Type Ii Diabetes ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Type Ii ◽  
Glucose Levels ◽  
First Degree Relatives

Objectives: To determine the frequency of impaired fasting glucose in first degree relatives of people with Type-II diabetes and its association with BMI. Methods: This cross-sectional study was conducted in Diabetic clinic of Shaikh Zayed Hospital, Lahore from July to December 2017. Individuals aged ≥35 years, first degree relatives of people with Type-II diabetes, were selected and their fasting blood glucose levels were checked twice a week apart. Study participants were divided into 3 groups. Group-I were those with normal fasting blood glucose (FBS: <100mg/dl), Group-II were those with impaired fasting glucose (100-125mg/dl), considered as high risk and Group-III included those who turned out to be having frank diabetes (FBS: ≥126mg/dl). Exclusion criteria were known diabetes and pregnancy. Proportions of impaired fasting glucose levels versus BMI were compared using Chi-square test. Significance was considered at P <0.001. Results: A total of hundred subjects were included in the study with the mean age of 44.27 years. Sixty percent participants had normal FBS, 31% showed impaired FBS and 09% had frank diabetes (P <0.001). Significant association was found between impaired fasting glucose and BMI, as with increasing BMI the frequency of impaired fasting glucose increases. Conclusion: First-degree relatives of people with Type-II diabetes showed higher frequency of impaired fasting glucose and obesity was an important risk factor. doi: https://doi.org/10.12669/pjms.36.3.57 How to cite this:Ali A, Taj A, Ahmed MU, Tabrez E. Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index. Pak J Med Sci. 2020;36(3):407-411. doi: https://doi.org/10.12669/pjms.36.3.57 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Assessment of Different Commercially Available Breads and Its Effect on Blood Glucose Levels of Healthy Individuals

2019 ◽  
pp. 1-5
Author(s):  
Bhavana Parmar ◽  
Rupali Sengupta
Keyword(s):  
Blood Glucose ◽  
Plasma Glucose ◽  
White Bread ◽  
Healthy Individuals ◽  
Glucose Response ◽  
High Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Response ◽  
Blood Glucose Levels ◽  
Breakfast Food

Background: Bread is one of the most commonly used breakfast food in India. The consumption also increased tremendously among children and adolescents as well as to some extent among adults. It was found that white bread raises the blood glucose levels and is not considered to be a healthy breakfast option especially for those with diabetes mellitus and those at risk of increased or borderline glucose intolerance. Aim: To assess different commercially available bread and its effect on Blood Glucose Levels of Healthy Individuals. Study Design: 5 bread varieties were chosen (namely White, Brown, Multigrain, Oats and Tutty fruity bread). The samples were fed to 30 subjects and their effect on blood glucose was analysed. Place of Study: The study was conducted in BMN College of Home Science, Matunga, Mumbai, India. Methodology: A pilot study was conducted on 30 samples to assess the Blood Glucose Levels of each type of bread. The subjects were then given bread-butter and the blood glucose response was re-tested at gap of 1 hour and 2 hour respectively. Each subject was given 5 different varieties of bread for 5 consecutive days i.e. White bread, Brown bread, Multigrain bread, Tutty Fruity bread and Oats bread. White bread is a universal standard, was used as a standard in the study.  The average plasma glucose levels were analysed in the study. Results: The average plasma glucose spike of the standard (White bread) was found to be the highest i.e (131.63 mg/dl).  It was observed that oats bread was found to have the lowest spike post 1 hour (103.43mg/dl) while tutty fruity bread exhibited a very high blood glucose response (123.90mg/dl) following the standard white bread. Conclusion: Investigations proved that oats bread should be consumed by people to mitigate metabolic syndrome due to a stressful lifestyle. Also, a healthy diet and exercise regime to be followed by subjects in the study.

scholarly journals Chitosan oligosaccharide (GO2KA1) improves postprandial glycemic response in subjects with impaired glucose tolerance and impaired fasting glucose and in healthy subjects: a crossover, randomized controlled trial

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Sarang Jeong ◽  
Jung Min Cho ◽  
Young-In Kwon ◽  
Seong-Chul Kim ◽  
Dong Yeob Shin ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Healthy Subjects ◽  
Fasting Glucose ◽  
Test Group ◽  
Postprandial Blood Glucose ◽  
Chitosan Oligosaccharide ◽  
Glucose Levels ◽  
Blood Glucose Levels

Abstract Background The antidiabetic and hypoglycemic effects of chitosan have been reported in previous studies. We have previously shown that chitosan oligosaccharide reduces postprandial blood glucose levels in vivo. We conducted a short-term crossover study to support the results of the previous study. Methods The study was a randomized, double-blind, controlled crossover trial completed at one clinical research site. Subjects with impaired glucose tolerance and impaired fasting glucose and healthy subjects were randomly assigned to consume one of two different experimental test capsules that differed in only the sample source (GO2KA1 vs placebo), and all subjects were instructed to consume the 75 g sucrose within 15 min. After a 7-day interval, the subjects consumed the other capsules that were not consumed on the first day. We assessed blood glucose levels using a 2-h oral sucrose tolerance test. The study was registered at clinicaltrials.gov (NCT03650023). Results The test group showed significantly lower blood glucose levels at 60 min (p = 0.010) and postprandial blood glucose areas under the curve (p = 0.012). The change in blood glucose levels at 60 min was significantly lower in the test group than in the placebo group (p = 0.017). Conclusions Based on the results of this study, the consumption of chitosan oligosaccharide (GO2KA1) supplements with a meal can effectively reduce postprandial blood glucose levels, which is relevant to the prevention of diabetes.

scholarly journals The Evaluation of Fasting Glucose Plasma (FGP) in Hypertensive Patients using Calcium Channel Blocker (CCB) Drug Class in Undata Regional Hospital

2021 ◽  
Vol 7 (2) ◽  
pp. 168-176
Author(s):  
Amelia Rumi ◽  
Anggun Fitriana
Keyword(s):  
Blood Glucose ◽  
Calcium Channel ◽  
Calcium Channel Blocker ◽  
Plasma Levels ◽  
Channel Blocker ◽  
Fasting Glucose ◽  
Hypertensive Patients ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Glucose Plasma

Background: Hypertension plays a major role in the development of heart disease which is one of the most leading causes of death worldwide. Antihypertensives must be selected carefully to avoid affecting metabolic parameters. A risky case involving the increase of glucose plasma levels using Calcium Channel Blocker (CCB) antihypertensive, amlodipine, has been reported. Objectives: This study aims to examine the effects of CCB treatments on blood glucose levels in hypertensive patients at the Undata District General Hospital of Central Sulawesi Province. Material and Methods: This study used a cross-sectional design with a prospective approach. The instruments & materials used in this study are Accu-Chek Performa glucometer along with the patient's blood sample material. The research subjects were 31 patients who met the inclusion criteria of 1) patients who had been treated with CCB therapy for 3 months, 2) were not diagnosed with diabetes mellitus, and 3) did not use drugs that might affect blood glucose levels. Results: The results showed an average value of fasting glucose plasma (FGP) levels of hypertension patients using CCB class showed an increase from baseline 124,619 mg/dL to 141,612 mg/dL with a difference of 16,993 mg/dL. Conclusions: Statistical analysis conducted also obtained a significance value of p 0,000 which indicates that the use of amlodipine can significantly increase fasting patients' glucose plasma levels. If observed clinically, this increase in fasting glucose plasma values ​​falls into the category of mild to moderate hyperglycemic.

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