Light and shadows of dietary protein restriction in elderly with Chronic Kidney Disease

Nutrition ◽  
2013 ◽  
Vol 29 (9) ◽  
pp. 1090-1093 ◽  
Author(s):  
Mauro Giordano ◽  
Tiziana Ciarambino ◽  
Pietro Castellino ◽  
Giuseppe Paolisso
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Dietary Protein ◽  
Protein Restriction ◽  
Dietary Protein Restriction

scholarly journals Effects of dietary protein restriction and oil type on the early progression of murine polycystic kidney disease

1992 ◽  
Vol 42 (4) ◽  
pp. 837-842 ◽  
Author(s):  
Harold M. Aukema ◽  
Malcolm R. Ogborn ◽  
Koji Tomobe ◽  
Hisahide Takahashi ◽  
Tsutomu Hibino ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Dietary Protein ◽  
Protein Restriction ◽  
Polycystic Kidney ◽  
Dietary Protein Restriction ◽  
Early Progression ◽  
Oil Type

Effect of recommended dietary protein restriction on the progression of kidney disease

2016 ◽  
Vol 252 ◽  
pp. e149
Author(s):  
C. Visinoni ◽  
A. Baragetti ◽  
I. Baragetti ◽  
C. Biazzi ◽  
K. Garlaschelli ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Dietary Protein ◽  
Protein Restriction ◽  
Dietary Protein Restriction ◽  
Progression Of Kidney Disease

scholarly journals Early dietary protein restriction slows disease progression and lengthens survival in mice with polycystic kidney disease.

1994 ◽  
Vol 5 (6) ◽  
pp. 1355-1360
Author(s):  
K Tomobe ◽  
D Philbrick ◽  
H M Aukema ◽  
W F Clark ◽  
M R Ogborn ◽  
...  
Keyword(s):  
Body Weight ◽  
Kidney Disease ◽  
Disease Progression ◽  
Polycystic Kidney Disease ◽  
Dietary Protein ◽  
Protein Restriction ◽  
Polycystic Kidney ◽  
Kidney Weight ◽  
Final Body Weight ◽  
Dietary Protein Restriction

The objective of these studies was to examine the effects of early dietary protein restriction on disease progression and survival in the DBA/2FG-pcy (pcy) mouse model of polycystic kidney disease. Male pcy mice of 70 days of age were fed either a normal protein (NP, 25% casein) or a low-protein (LP, 6% casein) diet for 105 days. At the end of the dietary treatment, kidney weight, kidney weight relative to body weight and kidney water contents were almost 50% lower, and relative renal phospholipid and triglyceride contents were almost 50% higher, in mice fed the LP diet, indicating a marked reduction in the progression of cystic disease. Morphometric analyses also revealed a lower total and percent cyst area in kidneys derived from mice on the LP compared with the NP diet. There were no significant differences in final body weight, urine volume and osmolality, GFR, proteinuria, or plasma levels of protein and urea between these two groups. In a second study, it was found that all mice fed an NP diet from 70 days of age onward had died by 310 days of age, compared with a 42% survival rate in LP-fed mice at this age. Overall, the mean lifespan for pcy mice on the LP diet was 24% longer than that for those mice on the NP diet (310 +/- 20 versus 251 +/- 16 days; P < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

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