Saturated fatty acids intake in relation to C-reactive protein, adiponectin, and leptin: A population-based study

Nutrition ◽  
2013 ◽  
Vol 29 (6) ◽  
pp. 892-897 ◽  
Author(s):  
Susana Santos ◽  
Andreia Oliveira ◽  
Susana Casal ◽  
Carla Lopes
BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Knut Hagen ◽  
Lars Jacob Stovner ◽  
Kristian Bernhard Nilsen ◽  
Espen Saxhaug Kristoffersen ◽  
Bendik Slagsvold Winsvold

Abstract Background Increased high sensitivity C- reactive protein (hs-CRP) levels have been found in many earlier studies on migraine, and recently also in persons with migraine and insomnia. The aim of this study was to see whether these findings could be reproduced in a large-scale population-based study. Methods A total of 50,807 (54%) out of 94,194 invited aged ≥20 years or older participated in the third wave of the Nord-Trøndelag Health Study study performed in 2006–2008. Among these, 38,807 (41%) had valid measures of hs-CRP and answered questions on headache and insomnia. Elevated hs-CRP was defined as > 3.0 mg/L. The cross-sectional association with headache was estimated by multivariate analyses using multiple logistic regression. The precision of the odds ratio (OR) was assessed with 95% confidence interval (CI). Results In the fully adjusted model, elevated hs-CRP was associated with migraine (OR 1.14, 95% CI 1.04–1.25) and migraine with aura (OR 1.15, 95% CI 1.03–1.29). The association was strongest among individuals with headache ≥15 days/month for any headache (OR 1.26, 95% CI 1.08–1.48), migraine (OR 1.62, 95% CI 1.21–2.17), and migraine with aura (OR 1.84, 95% CI 1.27–2.67). No clear relationship was found between elevated hs-CRP and headache less than 7 days/month or with insomnia. Conclusions Cross-sectional data from this large-scale population-based study showed that elevated hs-CRP was associated with headache ≥7 days/month, especially evident for migraine with aura.


2012 ◽  
Vol 54 (3) ◽  
pp. 462-468 ◽  
Author(s):  
Rafaella C.P. Luna ◽  
Christiane C.C. do Nascimento ◽  
Luiza S.R. Asciutti ◽  
Sylvia do C.C. Franceschini ◽  
Rosália Gouveia Filizola ◽  
...  

2005 ◽  
Vol 145 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Nuria Bertran ◽  
Jordi Camps ◽  
Joan Fernandez-Ballart ◽  
Victoria Arija ◽  
Natalia Ferre ◽  
...  

2010 ◽  
Vol 68 (6) ◽  
pp. 573-579 ◽  
Author(s):  
Timo Liukkonen ◽  
Mauno Vanhala ◽  
Jari Jokelainen ◽  
Sirkka Keinänen-Kiukaanniemi ◽  
Hannu Koponen ◽  
...  

2008 ◽  
Vol 23 ◽  
pp. S257 ◽  
Author(s):  
T. Liukkonen ◽  
M. Vanhala ◽  
J. Jokelainen ◽  
S. Keinänen-Kiukaanniemi ◽  
H. Koponen ◽  
...  

Author(s):  
Jørgen Jeppesen ◽  
Tine W. Hansen ◽  
Michael H. Olsen ◽  
Susanne Rasmussen ◽  
Hans lbsen ◽  
...  

Background C-reactive protein (CRP), a marker of inflammation, and insulin resistance (IR), a metabolic disorder, are closely related. CRP and IR have both been identified as significant risk factors of cardiovascular disease (CVD) after adjustment for conventional CVD risk factors. It is not clear whether CRP predicts CVD independent of IR. Design Prospective population-based study. Methods Two thousand three hundred and fifty-seven Danish men and women, recruited from the general population, aged 41–72 years, without major CVD at baseline were studied. Traditional and new risk factors were recorded at baseline. CRP was determined by a high-sensitivity assay, and IR was determined by the homoeostasis model assessment (HOMA-IR) method. Results Over a median follow-up of 9.4 years, the incidence of the prespecified CV event, defined as the composite event of CV death, nonfatal ischaemic heart disease and nonfatal stroke, amounted to 222 cases. In Cox proportional-hazard models, adjusted for age, sex, smoking habit, total cholesterol, waist circumference, levels of triglycerides and high-density lipoprotein-cholesterol, systolic and diastolic blood pressures, physical activity and HOMA-IR, the hazard ratio (95% confidence interval) of a CV event was 1.33 (1.14–1.55; 0.001) per standard deviation increase in log-transformed CRP level. In the same model, the hazard ratio of a CV event was 1.11 (1.02–1.21; P < 0.05) per standard deviation increase in HOMA-IR level. Conclusion In a general Danish population free of major CVD at baseline, both CRP and IR were significantly related to risk of CVD.


Sign in / Sign up

Export Citation Format

Share Document