Substitution of high monounsaturated fatty acid avocado for mixed dietary fats during an energy-restricted diet: Effects on weight loss, serum lipids, fibrinogen, and vascular function

Nutrition ◽  
2005 ◽  
Vol 21 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Z. Pieterse ◽  
J.C. Jerling ◽  
W. Oosthuizen ◽  
H.S. Kruger ◽  
S.M. Hanekom ◽  
...  
Author(s):  
Tereza Metelcová ◽  
Markéta Vaňková ◽  
Hana Zamrazilová ◽  
Milena Hovhannisyan ◽  
Eva Tvrzická ◽  
...  

1973 ◽  
Vol 44 (6) ◽  
pp. 601-604 ◽  
Author(s):  
J. I. Mann ◽  
G. S. Watermeyer ◽  
E. B. Manning ◽  
J. Randles ◽  
A. S. Truswell

1. Each of nine volunteers was fed three different diets. The percentage of total daily energy provided by fat, carbohydrate and protein remained constant, but the nature of the fat and carbohydrate was altered. The first diet contained ordinary amounts of sucrose and predominantly saturated fat. During the second dietary period, fat remained saturated, but the quantity of sucrose was increased at the expense of complex carbohydrate. In the third dietary period, the sucrose intake remained high, but fat was supplied chiefly in the polyunsaturated form. 2. A small but statistically significant increase of serum fasting cholesterol and triglyceride was observed during the second dietary period, but on the third diet levels of both lipids fell to concentrations not significantly different from those seen on the first diet.


2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Krista A. Varady ◽  
Vi T. Dam ◽  
Monica C. Klempel ◽  
Matthew Horne ◽  
Rani Cruz ◽  
...  

Author(s):  
Qingyi Jia ◽  
B Gisella Carranza Leon ◽  
Michael D Jensen

Abstract Context The factors that determine the recycling of free fatty acids (FFA) back into different adipose tissue depots via the direct storage pathway are not completely understood. Objective To assess the interactions between adipocyte factors and plasma FFA concentrations that determine regional FFA storage rates. Design We measured direct adipose tissue FFA storage rates before and after weight loss under high FFA (intravenous somatostatin and epinephrine) and low (intravenous insulin and glucose) FFA concentrations. Setting Mayo Clinic Clinical Research Unit. Patients Sixteen premenopausal women, BMI 30 - 37 kg/m 2. Intervention Comprehensive lifestyle weight loss program. Main Outcome Measure Direct FFA storage rates in upper and lower body subcutaneous fat. Results Over the entire range of FFA and under isolated conditions of elevated FFA concentrations the storage rates of FFA into upper and lower body subcutaneous fat per unit lipid were associated with concentrations, not adipocyte fatty acid storage factors. Under low FFA conditions, direct FFA storage rates were related to adipocyte CD36 content, not tissue level content of fatty acid storage factors. Weight loss did not change these relationships. Conclusions The regulation of direct FFA storage under low FFA concentration conditions appears to be at the level of the cell/adipocyte content of CD36, whereas under high FFA concentration conditions direct FFA storage at the tissue level is predicted by plasma FFA concentrations, independent of adipocyte size or fatty acid storage factors. These observations offer novel insights into how adipose tissue regulates direct FFA storage in humans.


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