Effect of ω-3 fatty acid-containing phospholipids on blood catecholamine concentrations in healthy volunteers: a randomized, placebo-controlled, double-blind trial

Nutrition ◽  
2005 ◽  
Vol 21 (6) ◽  
pp. 705-710 ◽  
Author(s):  
Kei Hamazaki ◽  
Miho Itomura ◽  
Mingming Huan ◽  
Hiroto Nishizawa ◽  
Shigeki Sawazaki ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Healthy Volunteers ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial

A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia

1989 ◽  
Vol 27 (3) ◽  
pp. 313-323 ◽  
Author(s):  
Krishna S. Vaddadi ◽  
Paul Courtney ◽  
Christopher J. Gilleard ◽  
Mehar S. Manku ◽  
David F. Horrobin
Keyword(s):  
Fatty Acid ◽  
Tardive Dyskinesia ◽  
Essential Fatty Acid ◽  
Double Blind Trial ◽  
Double Blind ◽  
Fatty Acid Supplementation ◽  
Acid Supplementation ◽  
Blind Trial

Percutaneous Treatment with a Mucopolysaccharide Polysulphate of Experimentally Induced Subcutaneous Haematomas in Man

1985 ◽  
Vol 53 (03) ◽  
pp. 343-345 ◽  
Author(s):  
B Larsson ◽  
S Fianu ◽  
A Jonasson ◽  
B Forsskåhl
Keyword(s):  
Healthy Volunteers ◽  
Subcutaneous Injection ◽  
Percutaneous Treatment ◽  
Double Blind Trial ◽  
Double Blind ◽  
Absorption Time ◽  
Blind Trial ◽  
The Difference ◽  
Objectively Measured ◽  
Experimentally Induced

SummaryIn a double blind trial on ten healthy volunteers, the efficacy of a topically applied mucopolysaccharide polysulphate* in the treatment of subcutaneous haematomas was assessed. Standardized haematomas were induced by subcutaneous injection of a mixture of autogenous blood and 125I-fibrinogen. The absorption of the haematoma, expressed as the removal of the labelled fibrin(ogen), could thus be objectively measured by the decrease in radioactivity.The results show an exponential absorption of these haematomas. The absorption time was reduced to about half compared with placebo, when treated topically with mucopolysaccharide polysulphate. The difference is statistically highly significant and is also considered clinically relevant.

O3-05-08: A randomized double-blind trial with omega-3 fatty acid treatment in mild to moderate Alzheimer's disease

2006 ◽  
Vol 2 ◽  
pp. S64-S64
Author(s):  
Yvonne Freund-Levi ◽  
Maria Eriksdotter Jonhagen ◽  
Tommy Cederholm ◽  
Hans Basun ◽  
Gerd Faxen-Irving ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fatty Acid ◽  
Acid Treatment ◽  
Double Blind Trial ◽  
Omega 3 ◽  
Double Blind ◽  
Omega 3 Fatty Acid ◽  
Blind Trial ◽  
Fatty Acid Treatment

scholarly journals Uptake of vitamin A in buccal mucosal cells after topical application of retinyl palmitate: a randomised, placebo-controlled and double-blind trial

2003 ◽  
Vol 90 (1) ◽  
pp. 69-74 ◽  
Author(s):  
U. Sobeck ◽  
A. Fischer ◽  
H. K. Biesalski
Keyword(s):  
Vitamin A ◽  
Healthy Volunteers ◽  
Squamous Metaplasia ◽  
Retinyl Palmitate ◽  
Double Blind Trial ◽  
Double Blind ◽  
Mucosal Epithelium ◽  
Blind Trial ◽  
Mucosal Cells ◽  
Plasma Retinol

Retinoids have been reported to produce regressions in metaplastic changes of the mucosal epithelium. In order to define the role of these micronutrients in the prevention of squamous metaplasia of the oral cavity, it is necessary to measure their uptake in target tissues such as the buccal mucosal epithelium. We demonstrated in a trial that retinyl palmitate applied topically via a toothpaste is taken up by buccal mucosal cells in young healthy volunteers. In the randomised, parallel-designed, placebo-controlled and double-blind trial, forty volunteers divided in two groups cleaned their teeth either with a placebo toothpaste or a retinyl palmitate-containing toothpaste (1 mg/g) for 56 d. Buccal mucosal cells samples were taken from the healthy volunteers during the retinyl palmitate application and the following wash-out phase to determine the concentration of retinyl palmitate and retinol by HPLC. Supplementary blood samples were taken from the volunteers on days 0 and 56 to investigate changes in plasma retinyl palmitate and retinol concentrations. Results from only thirty participants (sixteen placebo and fourteen treated subjects) were used in the statistical evaluation as the remaining sample results were spoiled by a technical defect during the HPLC analysis. A significant (P<0·05) uptake of retinyl palmitate in buccal mucosal cells after 7 d and a significant (P<0·05) increase of plasma retinol after 17 d was demonstrated in our present study. The uptake of retinyl palmitate and the following hydrolysis to retinol led to an enrichment of vitamin A in buccal mucosal cells.

99: Prulifloxacin Versus Levofloxacin in the Treatment of Chronic Bacterial Prostatitis: A Prospective, Randomized, Double-Blind Trial

2007 ◽  
Vol 177 (4S) ◽  
pp. 35-35
Author(s):  
Gianluca Giannarini ◽  
Andrea Mogorovich ◽  
Girolamo Morelli ◽  
Maurizio De Maria ◽  
Francesca Manassero ◽  
...  
Keyword(s):  
Double Blind Trial ◽  
Chronic Bacterial Prostatitis ◽  
Double Blind ◽  
Blind Trial ◽  
Bacterial Prostatitis
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