Higher obesity risk associated with the exon-8 insertion of the UCP2 gene in a Spanish case-control study

Nutrition ◽  
2004 ◽  
Vol 20 (6) ◽  
pp. 498-501 ◽  
Author(s):  
Amelia Marti ◽  
Ma Soledad Corbalán ◽  
Luis Forga L ◽  
Miguel A Martinez-González ◽  
J.Alfredo Martinez
2020 ◽  
Vol 43 (2) ◽  
Author(s):  
Cristine Dieter ◽  
Taís Silveira Assmann ◽  
Natália Emerim Lemos ◽  
Eloísa Toscan Massignam ◽  
Bianca Marmontel de Souza ◽  
...  

2011 ◽  
Vol 107 (4) ◽  
pp. 533-538 ◽  
Author(s):  
Adriana Moleres ◽  
M. Carmen Ochoa ◽  
Tara Rendo-Urteaga ◽  
M. Angel Martínez-González ◽  
M. Cristina Azcona San Julián ◽  
...  

The rs9939609 polymorphism of the fat mass and obesity-associated (FTO) gene has been widely associated with childhood obesity in several European cohorts. This association appears to be dependent on dietary macronutrients. Therefore, the aim of the present study was to evaluate whether dietary fatty acid intake distribution could interact with this FTO genetic variation and obesity in a Spanish case–control study of children and adolescents. A total of 354 Spanish children and adolescents aged 6–18 years (49 % males) were genotyped for the rs9939609 variant of the FTO gene. Anthropometric parameters were taken and energy intake was measured. We observed an interaction between the consumption of SFA (percentage of total energy) and PUFA:SFA ratio and obesity risk linked to the rs9939609 SNP of the FTO gene. In the study population of the present study, the risk allele carriers consuming more than 12·6 % SFA (of total energy) had an increased obesity risk compared with TT carriers. In a similar way, A allele carriers with an intake ratio lower than 0·43 PUFA:SFA presented a higher obesity risk than TT subjects. In summary, the present study reports for the first time the influence of dietary fatty acid distribution on the effect of the rs9939609 polymorphism of the FTO gene on children and adolescents' obesity risk.


1995 ◽  
Vol 54 (2) ◽  
pp. 198-207
Author(s):  
Mee Lian Wong ◽  
David Koh ◽  
James Lee ◽  
Moh Hoon Lee ◽  
Yoke Tien Fong

A case-control study was carried out in 1992 on 178 obese and 536 normal weight Chinese Singaporean adolescents to identify lifestyle behaviours associated with obesity. An inverse dose-response gradient of physical exercise to obesity was found in both genders. For females, obesity risk was statistically associated with those whose parents were food vendors, and for males, it was statistically associated with the practice of eating supper out regularly. Among the obese students, girls were statistically more likely than boys to eat in response to depression, stress and boredom.


2017 ◽  
Vol 81 (3) ◽  
pp. 106-116 ◽  
Author(s):  
Paula Costa-Urrutia ◽  
Carolina Abud ◽  
Valentina Franco-Trecu ◽  
Valentina Colistro ◽  
Martha Eunice Rodríguez-Arellano ◽  
...  

2006 ◽  
Vol 21 (8) ◽  
pp. 605-612 ◽  
Author(s):  
Olga Portolés ◽  
José Vicente Sorlí ◽  
Francesc Francés ◽  
Oscar Coltell ◽  
Jose I. González ◽  
...  

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