Which healthy lifestyle habits mitigate the risk of obesity and cardiometabolic risk factors in Caucasian children exposed to in utero adverse gestational factors?

2020 ◽  
Author(s):  
Soraya Saidj ◽  
Stephanie-M. Ruchat ◽  
Melanie Henderson ◽  
Vicky Drapeau ◽  
Marie-E. Mathieu
Keyword(s):  
Risk Factors ◽  
Cardiometabolic Risk ◽  
Healthy Lifestyle ◽  
In Utero ◽  
Cardiometabolic Risk Factors ◽  
Lifestyle Habits

scholarly journals Changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity and well-being in inactive women and men aged 57-74 years with obesity and cardiovascular risk – A 6-month complex lifestyle intervention with 6-month follow-up

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256631
Author(s):  
Laila A. Hopstock ◽  
Trygve S. Deraas ◽  
Andre Henriksen ◽  
Torsten Martiny-Huenger ◽  
Sameline Grimsgaard
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Lifestyle Intervention ◽  
Cardiometabolic Risk ◽  
Healthy Lifestyle ◽  
Well Being ◽  
Physical Capacity ◽  
Cardiometabolic Risk Factors

A key challenge in lifestyle interventions is long-term maintenance of favorable lifestyle changes. Middle-aged and older adults are important target groups. The purpose of this analysis was to investigate changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity, and well-being, in inactive middle-aged and older women and men with obesity and elevated cardiovascular disease risk, participating in an interdisciplinary single-arm complex lifestyle intervention pilot study. Participants were recruited from the population-based Tromsø Study 2015–2016 with inclusion criteria age 55–74 years, body mass index (BMI) ≥30kg/m2, sedentary lifestyle, no prior myocardial infarction and elevated cardiovascular risk. Participants (11 men and 5 women aged 57–74 years) underwent a 6-month intervention of two 1-hour group-sessions per week with instructor-led gradually intensified exercise (endurance and strength), one individual and three 2-hour group counselling sessions with nutritionist (Nordic Nutrition Recommendations) and psychologist (Implementation intention strategies). We investigated changes in adiposity (weight, BMI, body composition, waist circumference), physical activity (self-reported and via physical activity trackers), cardiometabolic risk factors (blood pressure, HbA1c, blood lipids), diet (intake of energy, nutrients, foods), physical capacity (aerobic capacity, muscle strength), and psychological well-being, measured at baseline and end-of-intervention, using mean-comparison paired t-tests. Further, we investigated self-reported healthy lifestyle maintenance six months after end-of-intervention, and monthly changes in daily step count, moderate-to-vigorous physical activity (MVPA) and total energy expenditure. From baseline to end-of-intervention, there was a mean decrease in weight, BMI, fat mass, waist circumference, intake of total- and saturated fat, and increase in lean mass, lateral pulldown and leg press. We detected no changes in mean levels of physical activity, cardiometabolic risk factors or well-being. Six months after end-of-intervention, 25% responded healthy lifestyle achievement and maintenance, while objectively measured physical activity remained unchanged. The results are useful for development of a protocol for a full-scale trial. Trial registration: The study was registered at www.ClinicalTrials.gov registry (NCT03807323).

scholarly journals Relationship between Dietary and Other Lifestyle Habits and Cardiometabolic Risk Factors in Men

2011 ◽  
Vol 3 (1) ◽  
pp. 30 ◽  
Author(s):  
Sayuri Katano ◽  
Yasuyuki Nakamura ◽  
Nagako Okuda ◽  
Yoshitaka Murakami ◽  
Nagako Chiba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Lifestyle Habits

scholarly journals Are Suboptimal in utero Conditions Associated with Obesity and Cardiometabolic Risk Factors in Caucasian children?

2020 ◽  
Author(s):  
Soraya Saidj ◽  
Melanie Henderson ◽  
Stephanie-May Ruchat ◽  
Gilles Paradis ◽  
Andraea Van Hulst ◽  
...  
Keyword(s):  
Risk Factors ◽  
Waist Circumference ◽  
Maternal Smoking ◽  
Cardiometabolic Risk ◽  
In Utero ◽  
Cardiometabolic Risk Factors ◽  
Smoking During Pregnancy ◽  
High Waist Circumference ◽  
Hypertensive Disorders ◽  
Maternal Smoking During Pregnancy

AbstractObjectiveTo explore the association between in utero exposure to suboptimal gestational factors (SGF;gestational diabetes mellitus, hypertensive disorders during pregnancy, maternal smoking during pregnancy), childhood obesity, and cardiometabolic risk factors.MethodsData were obtained from the “ QUebec Adiposity and Lifestyle InvesTigation in Youth” longitudinal study (QUALITY) composed of 630 Caucasian children recruited at age 8–10 (first visit V1; n=619) and followed-up 2 years later (V2; n=557). Simple logistic regression models were used.ResultsIn the cohort, maternal smoking during pregnancy was associated with higher odds of obesity (OR1=2.00, 95% CI 1.25-3.20, OR2=2.29, 95% IC 1.26-4.16) at both visit and with high waist circumference (OR1=1.96, 95% IC 1.24-3.1) at V1. Hypertensive disorders during pregnancy were associated with higher odds of obesity (OR1=2.37, 95% CI 1.17-4.80) at visit 1. Joint exposure to SGF was associated with higher odds of high waist circumference (OR1=1.42, 95% CI 1.06-1.91) at V1, obesity (OR2= 1.63, 95% IC 1.153-2.32) at V2 and low level of HDL (OR2=1.45, 95% IC 1.04-2.03) at V2. Analysis’ stratification by sex revealed that boys were more adversely affected by exposure to combined SGF while girls were more affected by exposure to maternal smoking during pregnancy.ConclusionIn utero exposure to an independent or combined SGF is associated with adverse adipose and cardiometabolic profiles in children, with sex specificities.

Increased monocyte to HDL cholesterol ratio in vitamin B12 deficiency: is it related to cardiometabolic risk?

2020 ◽  
pp. 1-8
Author(s):  
Sanem Kayhan ◽  
Nazli Gulsoy Kirnap ◽  
Mercan Tastemur
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Uric Acid ◽  
Vitamin B12 ◽  
Cardiometabolic Risk ◽  
Vitamin B12 Deficiency ◽  
Left Ventricular ◽  
Cardiometabolic Risk Factors ◽  
B12 Deficiency ◽  
Deficiency Group

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.

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