scholarly journals Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts

2020 ◽  
Vol 30 (12) ◽  
pp. 2252-2261
Author(s):  
Boukje C. Eveleens Maarse ◽  
Nellie Y. Loh ◽  
Fredrik Karpe ◽  
Frits R. Rosendaal ◽  
Diana van Heemst ◽  
...  
Keyword(s):  
Population Based ◽  
Outdoor Temperature ◽  
Bright Sunlight

scholarly journals Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts

2019 ◽  
Vol 104 (7) ◽  
pp. 2903-2910 ◽  
Author(s):  
Raymond Noordam ◽  
Ashna Ramkisoensing ◽  
Nellie Y Loh ◽  
Matt J Neville ◽  
Frits R Rosendaal ◽  
...  
Keyword(s):  
Population Based ◽  
European Population ◽  
Outdoor Temperature ◽  
Bright Sunlight ◽  
Cardiometabolic Traits

scholarly journals Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts

2019 ◽  
Author(s):  
Boukje C Eveleens Maarse ◽  
Nellie Y. Loh ◽  
Fredrik Karpe ◽  
Frits R Rosendaal ◽  
Diana van Heemst ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Population Based ◽  
Cardiometabolic Health ◽  
Outdoor Temperature ◽  
Cross Sectional ◽  
Lipoprotein Subclasses ◽  
Bright Sunlight

AbstractContext: Outdoor temperature and bright sunlight may directly and/or indirectly modulate systemic metabolism.Objective: We assessed the associations between outdoor temperature and bright sunlight duration with metabolomics.Design: meta-analysis of two cross-sectional studies.Setting: Two population-based European cohort studies.Patients or other participants: Non-diabetic individuals from the Oxford BioBank (OBB; N=6,368; mean age 47.0 years, males 44%) and the Netherlands Epidemiology of Obesity (NEO; N=5,916; mean age 55.6 years, males 43%) studies.Intervention(s): Data on mean outdoor bright sunlight and temperature collected from local weather stations in the week prior to blood sampling.Main Outcome Measure(s): Serum levels of 148 metabolites measured using NMR spectroscopy, including 14 lipoprotein subclasses.Statistical analyses: Multivariable linear regression analyses adjusted for age, sex, body mass index, season and either outdoor temperature or bright sunlight. Summary statistics from the OBB and NEO cohorts were combined using fixed-effect meta-analyses.Results: A higher mean outdoor temperature was associated with increased concentrations of lipoprotein (sub)particles and certain amino acids such as phenylalanine and leucine. In contrast, longer mean hours of bright sunlight were specifically associated with lower concentrations of very low density lipoprotein (sub)particles. The direction of effects was consistent between the OBB and NEO, although effect sizes were generally larger in the OBB.Conclusions: Increased bright sunlight duration is associated with an improved metabolic profile whilst higher outdoor temperature may adversely impact cardiometabolic health.

Seasonal Variation in Fibrinogen in the Rotterdam Study

1997 ◽  
Vol 78 (03) ◽  
pp. 1059-1062 ◽  
Author(s):  
J G van der Bom ◽  
M P M de Maat ◽  
M L Bots ◽  
A Hofman ◽  
C Kluft ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Seasonal Variation ◽  
Hdl Cholesterol ◽  
The Elderly ◽  
Population Based ◽  
Seasonal Difference ◽  
Risk Indicator ◽  
Rotterdam Study ◽  
Outdoor Temperature ◽  
Cross Sectional

SummaryAs evidence accumulates to implicate fibrinogen as a risk indicator for cardiovascular disease, it is of interest to study its seasonal variation. A population based cross-sectional study was performed among participants of the Rotterdam Study, a cohort of 7,983 men and women, aged 55 years and over. Fibrinogen levels were measured by the prothrombin time derived method in the first 2,325 participants of the study. Fibrinogen levels were considerably higher in winter. The seasonal difference was 0.34 g/1 (95% confidence interval 0.29,0.39) and was more pronounced in subjects aged 75 years and over than in subjects aged 55 to 75 years, 0.43 g/1 (0.34,0.52) and 0.29 g/1 (0.24,0.35), respectively. Additional adjustment for body mass index, systolic and diastolic blood pressure, and total and HDL cholesterol did not materially change the findings. After adjustment for seasons, outdoor temperature was not associated with fibrinogen. Adjustment for outdoor temperature did not change the seasonal variation of fibrinogen, seasonal difference 0.31 g/1 (0.24, 0.37). In conclusion, fibrinogen levels are highest in Winter. The seasonal variation of fibrinogen is more pronounced in the elderly. Outdoor temperature does not seem to play a role in the seasonal variation of fibrinogen. Seasonal variation of fibrinogen may partly explain the increased cardiovascular disease mortality in Winter.

Risk of fracture in Crohn's disease: A population-based study

2001 ◽  
Vol 120 (5) ◽  
pp. A628-A628
Author(s):  
E LOFTUSJR ◽  
C CROWSON ◽  
W SANDBORN ◽  
W TREAMINE ◽  
W OFALLON ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Population Based Study ◽  
Risk Of Fracture

1419: Population-Based PSA Velocity

2007 ◽  
Vol 177 (4S) ◽  
pp. 468-468
Author(s):  
David Connolly ◽  
Amanda Black ◽  
Liam J. Murray ◽  
Anna Gavin ◽  
Patrick F. Keane
Keyword(s):  
Population Based ◽  
Psa Velocity

264: Population-Based Study of Renal Cell Carcinoma and Prostate Cancer in the Same Patient

2005 ◽  
Vol 173 (4S) ◽  
pp. 73-73 ◽  
Author(s):  
Daniel A. Barocas ◽  
Farhang Rabbani ◽  
Douglas S. Scherr ◽  
E. Darracott Vaughan
Keyword(s):  
Prostate Cancer ◽  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Population Based ◽  
Population Based Study

535: Population-Based Case-Control Study of PSA and DRE Screening on Prostate Cancer Mortality

2005 ◽  
Vol 173 (4S) ◽  
pp. 146-146
Author(s):  
Eric J. Bergstralh ◽  
Rosebud O. Roberts ◽  
Michael M. Lieber ◽  
Sara A. Farmer ◽  
Jeffrey M. Slezak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Mortality ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Prostate Cancer Mortality ◽  
Control Study

1480: The Association of Body Mass Index and Serum Prostate Specific Antigen Levels in a Population-Based Study

2005 ◽  
Vol 173 (4S) ◽  
pp. 401-401
Author(s):  
Javier Hernandez ◽  
Jacques Baillargeon ◽  
Brad Pollock ◽  
Alan R. Kristal ◽  
Patrick Bradshaw ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Prostate Specific Antigen ◽  
Body Mass ◽  
Specific Antigen ◽  
Population Based ◽  
Population Based Study ◽  
Serum Prostate Specific Antigen
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