scholarly journals Diabetes as a risk factor for greater COVID-19 severity and in-hospital death: A meta-analysis of observational studies

2020 ◽  
Vol 30 (8) ◽  
pp. 1236-1248 ◽  
Author(s):  
Alessandro Mantovani ◽  
Christopher D. Byrne ◽  
Ming-Hua Zheng ◽  
Giovanni Targher
Keyword(s):  
Risk Factor ◽  
Observational Studies ◽  
Meta Analysis ◽  
Hospital Death

scholarly journals Mortality rate and predictors of Stroke: A Meta-Analysis and Systematic Review

2019 ◽  
Author(s):  
Amanual Getnet Mersha ◽  
Tadesse Melaku Abegaz ◽  
Mohammed Assen Seid ◽  
Eyob Alemayehu Gebreyohannes ◽  
Akshaya Srikanth Bhagavath ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Observational Studies ◽  
Meta Analysis ◽  
Random Effect ◽  
Stroke Mortality ◽  
Stroke Event ◽  
Meta Analyses ◽  
Random Effect Models ◽  
Overall Mortality

Abstract Background Global data on stroke mortality remained to be sparse. In light of this, we aimed to conduct a Meta-analysis and systematic review of observational studies to estimate the mortality of stroke and to identify risk factors that predispose patients for stroke-related death.Methods This study was conducted based on the Meta-Analyses of Observational Studies in Epidemiology (MOOSE) guidelines. Overall mortality, in-hospital and 30- day mortality due to stroke were the primary outcome measures of the study. The meta-analysis was performed using Stata (Version 14, Stata Corp, College Station, Texas). Random-effect models were used for estimating pooled effects.Findings Overall, thirty two studies assessed overall mortality due to stroke. A total number of 2,885, 126 patients were recruited for the study. Pooled estimate indicated that the overall mortality of stroke was reported to be 20% (19%-22%). Whereas, the 30-day and In-hospital mortality were found to be 18% (16%-20%) and 16% (16%-19%), respectively. A subgroup analysis revealed that Africa registered the highest stroke-related death 29% (23%-36%). Hypertension was found to be an important risk factor for mortality secondary to stroke 61.9% (52.8%-71.1%).Conclusion Overall mortality of stroke was estimated to be twenty percent. The burden of stroke mortality was prominent in Africa region. Hypertension remained to be an independent risk factor for stroke mortality. Mortality of stroke can be minimized by establishing stroke centers that promptly deliver emergency management of stroke event.

scholarly journals Pregnancy as a risk factor for severe outcomes from influenza virus infection: A systematic review and meta-analysis of observational studies

Vaccine ◽  
2017 ◽  
Vol 35 (4) ◽  
pp. 521-528 ◽  
Author(s):  
Dominik Mertz ◽  
Johanna Geraci ◽  
Judi Winkup ◽  
Bradford D. Gessner ◽  
Justin R. Ortiz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Influenza Virus ◽  
Risk Factor ◽  
Virus Infection ◽  
Observational Studies ◽  
Meta Analysis ◽  
Influenza Virus Infection

Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies

2009 ◽  
Vol 69 (01) ◽  
pp. 70-81 ◽  
Author(s):  
D Sugiyama ◽  
K Nishimura ◽  
K Tamaki ◽  
G Tsuji ◽  
T Nakazawa ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factor ◽  
Observational Studies ◽  
Meta Analysis ◽  
Smoking History ◽  
Random Effects Model ◽  
Relative Risks ◽  
Adjustment Factors ◽  
Participant Characteristics ◽  
Heavy Smokers

Objectives:To assess whether smoking is a risk factor for developing rheumatoid arthritis (RA).Design:Meta-analysis.Method:Data sources were observational studies that examined the association between smoking history and the risk of developing RA identified through Medline and EMBASE (from 1966 to December 2006), relevant books and a reference search. Two authors independently extracted the following: authors’ names, publication year, sample size, participant characteristics, odds ratios (OR) or relative risks, adjustment factors, study design and area where the study was conducted. Data syntheses were based upon random effects model. Summarised syntheses effects were expressed by OR.Results:Sixteen studies were selected from among 433 articles. For men, summary OR for ever, current and past smokers were 1.89 (95% CI 1.56 to 2.28), 1.87 (1.49 to 2.34) and 1.76 (1.33 to 2.31), respectively. For rheumatoid factor-positive (RF+) RA, summary OR for ever, current and past smokers were 3.02 (2.35 to 3.88), 3.91 (2.78 to 5.50) and 2.46 (1.74 to 3.47), respectively. Summary OR for 20 or more pack-years of smoking was 2.31 (1.55 to 3.41). For women, summary OR for ever, current and past smokers were 1.27 (1.12 to 1.44), 1.31 (1.12 to 1.54) and 1.22 (1.06 to 1.40), respectively. For RF+ RA, summary OR for ever, current and past smokers were 1.34 (0.99 to 1.80), 1.29 (0.94 to 1.77) and 1.21 (0.83 to 1.77). Summary OR for 20 or more pack-years of smoking was 1.75 (1.52 to 2.02).Conclusion:Smoking is a risk factor for RA, especially RF+ RA men and heavy smokers.

scholarly journals Periodontitis as a risk factor for peri-implantitis: Systematic review and meta-analysis of observational studies

2018 ◽  
Vol 79 ◽  
pp. 1-10 ◽  
Author(s):  
Sérgio Diniz Ferreira ◽  
Carolina Castro Martins ◽  
Sergio Antonucci Amaral ◽  
Thais Ribeiral Vieira ◽  
Bárbara Nascimento Albuquerque ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Observational Studies ◽  
Meta Analysis

Thyroid nodules as a risk factor for thyroid cancer in patients with Graves’ disease: A systematic review and meta‐analysis of observational studies in surgically treated patients

2019 ◽  
Vol 91 (4) ◽  
pp. 571-577 ◽  
Author(s):  
Anastasios Papanastasiou ◽  
Konstantinos Sapalidis ◽  
Dimitrios G. Goulis ◽  
Nikolaos Michalopoulos ◽  
Evangelia Mareti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Thyroid Cancer ◽  
Observational Studies ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
Graves Disease

scholarly journals Head Injury as a Risk Factor for Dementia and Alzheimer’s Disease: A Systematic Review and Meta-Analysis of 32 Observational Studies

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169650 ◽  
Author(s):  
Yanjun Li ◽  
Yongming Li ◽  
Xiaotao Li ◽  
Shuang Zhang ◽  
Jincheng Zhao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Head Injury ◽  
Observational Studies ◽  
Meta Analysis

scholarly journals Is liver transplantation a risk factor for cardiovascular disease? a meta-analysis of observational studies

2012 ◽  
Vol 18 (10) ◽  
pp. 1140-1146 ◽  
Author(s):  
Surabhi Madhwal ◽  
Ashish Atreja ◽  
Mazen Albeldawdi ◽  
Rocio Lopez ◽  
Anthony Post ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Liver Transplantation ◽  
Risk Factor ◽  
Observational Studies ◽  
Meta Analysis

scholarly journals Risk Factors for Plantar Fasciitis in Physically Active Individuals: A Systematic Review and Meta-analysis

2021 ◽  
pp. 194173812097097
Author(s):  
Karrie L. Hamstra-Wright ◽  
Kellie C. Huxel Bliven ◽  
R. Curtis Bay ◽  
Burcu Aydemir
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Body Mass Index ◽  
Risk Factor ◽  
Range Of Motion ◽  
Body Mass ◽  
Plantar Fasciitis ◽  
Observational Studies ◽  
Meta Analysis ◽  
Physically Active

Context: Plantar fasciitis (PF) is a common condition in active individuals. The lack of agreement on PF etiology makes treatment challenging and highlights the importance of understanding risk factors for preventive efforts. Objective: The purpose of this systematic review and meta-analysis was to determine what factors may put physically active individuals at risk of developing PF. Data Sources: CENTRAL, CINAHL, EMBASE, Gray Lit, LILACS, MEDLINE (PubMed), ProQuest, Scopus, SPORTDiscus, and Web of Science were searched through April 2018 and updated in April 2020. Study Selection: Studies were included if they were original research investigating PF risk factors, compared physically active individuals with and without PF, were written in English, and were accessible as full-length, peer-reviewed articles. Study Design: Systematic review and meta-analysis. Level of Evidence: Level 3, because of inconsistent definitions and blinding used in the included observational studies. Data Extraction: Data on sample characteristics, study design and duration, groups, PF diagnosis, and risk factors were extracted. The methodological quality of the studies was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology statement. When means and standard deviations of a particular risk factor were presented 2 or more times, that risk factor was included in the meta-analysis. Results: Sixteen studies were included in the systematic review and 11 risk factors in the meta-analysis. Increased plantarflexion range of motion (weighted mean difference [MD] = 7.04°; 95% CI, 5.88-8.19; P < 0.001), body mass index (MD = 2.13 kg/m2; 95% CI, 1.40-2.86; P < 0.001; I2 = 0.00%), and body mass (MD = 4.52 kg; 95% CI, 0.55-8.49; P = 0.026) were risk factors for PF. Conclusion: Interventions focused on addressing a greater degree of plantarflexion range of motion, body mass index, and body mass and their load on the force-absorbing plantar surface structures may be a good starting point in the prevention and treatment of active individuals with PF.

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