Serum 25-hydroxyvitamin D is associated with major cardiovascular risk factors and cardiac structure and function in patients with coronary artery disease

2015 ◽  
Vol 25 (5) ◽  
pp. 471-478 ◽  
Author(s):  
M.P. Pekkanen ◽  
O. Ukkola ◽  
P. Hedberg ◽  
O.P. Piira ◽  
S. Lepojärvi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Cardiac Structure And Function ◽  
Artery Disease ◽  
And Function

scholarly journals The impact of cardiovascular risk factors on cardiac structure and function: Insights from the UK Biobank imaging enhancement study

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185114 ◽  
Author(s):  
Steffen E. Petersen ◽  
Mihir M. Sanghvi ◽  
Nay Aung ◽  
Jackie A. Cooper ◽  
José Miguel Paiva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Uk Biobank ◽  
Cardiac Structure And Function ◽  
The Uk ◽  
And Function ◽  
The Impact

scholarly journals Changes in cardiac structure and function with aging

2022 ◽  
Author(s):  
Tanushree Agrawal ◽  
Sherif F. Nagueh
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Cardiac Remodeling ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Physiological Changes ◽  
Age Related ◽  
Cardiac Structure And Function ◽  
And Function

Aging is associated with progressive changes in cardiac structure and function. The prevalence of cardiovascular risk factors and disease also increases profoundly with advancing age. Therefore, understanding the spectrum of physiological changes in the aging heart is crucial for the identification and risk stratification of cardiovascular disease. In this review, we discuss echocardiographic features of age-related cardiac remodeling.

Stress Echocardiography

2018 ◽  
pp. 326-334
Author(s):  
L. Samuel Wann
Keyword(s):  
Cardiac Disease ◽  
Stress Echocardiography ◽  
Comprehensive Evaluation ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Ultrasound Assessment ◽  
Cardiac Structure And Function ◽  
Artery Disease ◽  
Sensitivity Specificity ◽  
And Function

The Stress Echocardiography chapter reviews the opportunities to increase sensitivity and specificity of stress testing for the diagnosis of ischemic heart disease with adjunctive echocardiography with exercise or dobutamine-atropine stress. Baseline imaging prior to stress should include a comprehensive evaluation of cardiac structure and function, including the assessment of valvular disease with Doppler echocardiography. The chapter discusses stress echocardiography protocols; image analysis and reporting; sensitivity, specificity, and accuracy for detection of coronary artery disease; and evaluation of noncoronary cardiac disease. New and developing echocardiographic technology, including ultrasound assessment of myocardial perfusion, real-time 3D echocardiographic, and strain imaging are also discussed.

scholarly journals Retinal microvascular structure and function in patients with risk factors of atherosclerosis and coronary artery disease

2014 ◽  
Vol 233 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Ali H. Al-Fiadh ◽  
Omar Farouque ◽  
Ryo Kawasaki ◽  
T.T. Nguyen ◽  
Nazim Uddin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Structure And Function ◽  
Artery Disease ◽  
And Function

Cardioprotective potential of lithium and role of fractalkine in euthymic patients with bipolar disorder

2021 ◽  
pp. 000486742110625
Author(s):  
Pao-Huan Chen ◽  
Cheng-Yi Hsiao ◽  
Shuo-Ju Chiang ◽  
Ruei-Siang Shen ◽  
Yen-Kuang Lin ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cardiovascular Risk ◽  
Lithium Treatment ◽  
Structure And Function ◽  
Cardiac Structure ◽  
High Cardiovascular Risk ◽  
Cohen’S D ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Cohen's D

Objective: Over a half century, lithium has been used as the first-line medication to treat bipolar disorder. Emerging clinical and laboratory studies suggest that lithium may exhibit cardioprotective effects in addition to neuroprotective actions. Fractalkine (CX3CL1) is a unique chemokine associated with the pathogenesis of mood disorders and cardiovascular diseases. Herein we aimed to ascertain whether lithium treatment is associated with favorable cardiac structure and function in relation to the reduced CX3CL1 among patients with bipolar disorder. Methods: We recruited 100 euthymic patients with bipolar I disorder aged over 20 years to undergo echocardiographic study and measurement of plasma CX3CL1. Associations between lithium treatment, cardiac structure and function and peripheral CX3CL1 were analyzed according to the cardiovascular risk. The high cardiovascular risk was defined as (1) age ⩾ 45 years in men or ⩾ 55 years in women or (2) presence of concurrent cardiometabolic diseases. Results: In the high cardiovascular risk group ( n = 61), patients who received lithium as the maintenance treatment had significantly lower mean values of left ventricular internal diameters at end-diastole (Cohen’s d = 0.65, p = 0.001) and end-systole (Cohen’s d = 0.60, p = 0.004), higher mean values of mitral valve E/A ratio (Cohen’s d = 0.51, p = 0.019) and superior performance of global longitudinal strain (Cohen’s d = 0.51, p = 0.037) than those without lithium treatment. In addition, mean plasma levels of CX3CL1 in the high cardiovascular risk group were significantly lower among patients with lithium therapy compared with those without lithium treatment ( p = 0.029). Multiple regression models showed that the association between lithium treatment and mitral value E/A ratio was contributed by CX3CL1. Conclusion: Data from this largest sample size study of the association between lithium treatment and echocardiographic measures suggest that lithium may protect cardiac structure and function in patients with bipolar disorder. Reduction of CX3CL1 may mediate the cardioprotective effects of lithium.

Sign in / Sign up

Export Citation Format

Share Document