Metabolic syndrome and long-term cardiovascular outcomes in NSTEMI with unstable angina

2014 ◽  
Vol 24 (2) ◽  
pp. 176-182 ◽  
Author(s):  
S. Kul ◽  
H. Uyarel ◽  
M. Gul ◽  
O.T. Kucukdaglı ◽  
A. Bacaksiz ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Unstable Angina ◽  
Cardiovascular Outcomes

scholarly journals An Exploratory Analysis of Criteria for the Metabolic Syndrome and Its Prediction of Long-term Cardiovascular Outcomes

2005 ◽  
Vol 162 (5) ◽  
pp. 438-447 ◽  
Author(s):  
Cynthia J. Girman ◽  
Jacqueline M. Dekker ◽  
Thomas Rhodes ◽  
Giel Nijpels ◽  
Coen D. A. Stehouwer ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Outcomes ◽  
Exploratory Analysis ◽  
The Metabolic Syndrome

scholarly journals Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kosuke Honda ◽  
Satoru Kuriyama ◽  
Kimiyoshi Ichida ◽  
Tomoko Nakano ◽  
Naoki Sugano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Renal Function ◽  
Uric Acid ◽  
Cohort Study ◽  
Serum Uric Acid Level ◽  
Human Growth ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort

Abstract Background Insulin-like growth factor-1 (IGF-1) acts on glucose and protein metabolism and human growth and also influences blood pressure and renal function. This study investigated whether the single-nucleotide polymorphism of IGF-1, rs35767, plays a role in metabolic syndrome indicators, including blood pressure, glucose metabolism, uric acid levels, and renal function. Methods In this retrospective longitudinal cohort study, blood samples from 1506 Japanese individuals were collected and used for genotyping for variant rs35767: T > C in the IGF-1 upstream promoter. Data were analyzed to identify associations between IGF-1 genotypes and patient biochemical parameters, including the components of metabolic syndrome and the long-term change in renal function. Results The cohort rs35767 genotypes included 650 CC carriers (43.2%), 687 TC carriers (45.6%), and 169 TT carriers (11.2%). Multiple regression analysis revealed no association between IGF-1 genotype and blood pressure, glycated hemoglobin level, and serum uric acid level. However, in females, blood pressure was negatively correlated with the TT genotype. Longitudinal observation revealed that the decline in eGFR over 10 years was greater in TT (− 18.51 ± 1.04 mL/min/1.73m2) than in CC carriers (− 16.38 ± 0.52 mL/min/1.73m2; P < 0.05). Conclusion The present study suggests that renal function declines faster in individuals with the TT genotype at the IGF-1 rs35767 locus than in those with the CC genotype, suggesting that the TT genotype is associated with the long-term chronological decline in renal function.

Prevalence of the metabolic syndrome in women with a previous diagnosis of polycystic ovary syndrome: long-term follow-up

2011 ◽  
Vol 96 (5) ◽  
pp. 1271-1274 ◽  
Author(s):  
Miriam Hudecova ◽  
Jan Holte ◽  
Matts Olovsson ◽  
Anders Larsson ◽  
Christian Berne ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
The Metabolic Syndrome ◽  
Previous Diagnosis ◽  
Long Term Follow Up

scholarly journals The TIMI risk index predicts long-term mortality in patients admitted with primary unstable angina

2003 ◽  
Vol 41 (6) ◽  
pp. 349-350
Author(s):  
David O'Halloran ◽  
Christopher J. O'Donnell ◽  
Robert P. Giugliano ◽  
Carlos A. Camargo ◽  
Larry Allen ◽  
...  
Keyword(s):  
Unstable Angina ◽  
Risk Index ◽  
Long Term Mortality

scholarly journals Short-term and long-term cardiovascular risk, metabolic syndrome and HIV in Tanzania

Heart ◽  
2016 ◽  
Vol 102 (15) ◽  
pp. 1200-1205 ◽  
Author(s):  
Justin R Kingery ◽  
Yona Alfred ◽  
Luke R Smart ◽  
Emily Nash ◽  
Jim Todd ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Short Term
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