Postmenopausal women with carotid atherosclerosis: Potential role of the serum calcium levels

2013 ◽  
Vol 23 (11) ◽  
pp. 1141-1146 ◽  
Author(s):  
T. Montalcini ◽  
R. Terracciano ◽  
S. Romeo ◽  
D. Foti ◽  
E. Gulletta ◽  
...  
2020 ◽  
Vol 26 ◽  
Author(s):  
Areti Sofogianni ◽  
Konstantinos Tziomalos ◽  
Triantafyllia Koletsa ◽  
Apostolos G. Pitoulias ◽  
Lemonia Skoura ◽  
...  

: Carotid atherosclerosis is responsible for a great proportion of ischemic strokes. Early identification of unstable or vulnerable carotid plaques and therefore of patients at high risk for stroke is of significant medical and socioeconomical value. We reviewed the current literature and discuss the potential role of the most important serum biomarkers in identifying patients with carotid atherosclerosis who are at high risk for atheroembolic stroke.


2019 ◽  
Vol Volume 14 ◽  
pp. 743-752
Author(s):  
Ningyin Li ◽  
Ruixin Ma ◽  
Shixiong Wang ◽  
Yang Zhao ◽  
Ping Wang ◽  
...  

2005 ◽  
Vol 1 (2) ◽  
pp. 191-193 ◽  
Author(s):  
Anita H Clayton

Evaluation of: van Anders SM, Chernick AB, Chernick BA et al.: Preliminary clinical experience with androgen administration for pre- and postmenopausal women with hypoactive sexual desire. J. Sex Marital Ther. 31, 173–185 (2005). There has been significant debate about the potential role of androgens in the treatment of hypoactive sexual desire in women. In this study, pre- and postmenopausal women with hypoactive sexual desire were age-matched with women without such complaints (n = 33). The treatment group received 100 mg of testosterone cypionate intramuscularly once a month for 3 months. Measures of salivary testosterone indicated no difference between groups at baseline, with an increase in testosterone levels in the hypoactive sexual desire group post-treatment. While significant differences existed between the two groups at baseline in scores on the Sexual Desire Inventory, the treated women demonstrated a significant increase in sexual desire post-treatment, with no difference in Sexual Desire Inventory scores at study end point. This study suggests that supplemental testosterone may improve sexual desire in women with hypoactive sexual desire without hypoandrogenism.


Open Medicine ◽  
2011 ◽  
Vol 6 (2) ◽  
pp. 185-189
Author(s):  
Aleksandar Dimić ◽  
Stojanovic Sonja ◽  
Nedovic Jovan ◽  
Stankovic Aleksandra ◽  
Stamenkovic Bojana ◽  
...  

AbstractEarly diagnosis of osteoporosis and estimation of subjects that are at high risk for fracture, is neccesary for osteoporosis treatment. Dual-energy X-ray absorptometry (DXA) is a modern method for bone mineral density (BMD) evaluation. However, along BMD, clinical risk factors may significantly influence fracture development. Therefore, FRAX algorithm was designed for the assessment of a ten-year risk for serious osteoporotic fractures (SOF), as well as hip fractures. In the current study, we tried to evaluate the possible lumbal spine and hip BMD influence on ten year risk for SOF and hip fractures and potential role of FRAX in predicting the therapy in postmenopausal women with osteopenia. We performed the study on 385 postmenopausal women. According to the DXA measurements, at the lumbal (L) spine (L1–L4) and hip (femor neck), patients were then classified as normal, osteopenic, or osteoporotic. BMD evaluation included the L spine and the hip (subgroup 1), and only on the L spine (subgroup 2). By filling up the FRAX questionnaire, a ten-year risk for SOF fracture and hip fracture was calculated. BMD evaluation, in complete patient’s group and in subgroup 1, resulted in the highest number of osteoporosis (61.04%, 48.08%, retrospectively), while ospeopenia was a main finding in subgroup 2. In the subgroup 1, a high risk for SOF and hip fracture was detected in 16.45% and with high risk for hip fracture in 11.38% subjects. In subgroup 2, only high risk for hip fracture was observed in 3.16% subjects, indicating the active medicament treatment. Simultaneously, correlation of BMD results with FRAX values for SOF and hip fracture, showed significant negative correlation (p<0.001). Obtained results showed significant role of femur neck BMD evaluation in predicting the future factors, which may, together with FRAX analysis, improve the therapy approach in postmenopausal women with ospeopenia.


Angiology ◽  
2002 ◽  
Vol 53 (3) ◽  
pp. 279-285 ◽  
Author(s):  
K. Kalogeropoulou ◽  
G. Mortzos ◽  
I. Migdalis ◽  
C. Velentzas ◽  
D.P. Mikhailidis ◽  
...  

2013 ◽  
Vol 2 (4) ◽  
pp. 55 ◽  
Author(s):  
Nik Hazlina Nik Hussain ◽  
Azidah Abdul Kadir

<p><em>Labisia pumila</em> (Myrsinaceae), also called Kacip Fatimah, is a herbal medicine that has been widely used in South East Asian communities mainly for women’s health. The extensive use of this plant has led to many speculations and studies on its phytoestrogenic properties. This review highlights the studies that involved<em> Labisia pumila,</em> which include phytochemical profiling and its safety. In addition, we also look into its use as an alternative to hormonal therapy in postmenopausal women, and its role in cardiovascular protection and osteoporosis. Further studies are needed to highlight the potential benefits of this plant in promoting advantageous health properties. <em></em></p>


2007 ◽  
Vol 17 (10) ◽  
pp. 705-711 ◽  
Author(s):  
T. Montalcini ◽  
G. Gorgone ◽  
C. Gazzaruso ◽  
G. Sesti ◽  
F. Perticone ◽  
...  

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.


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