Serum 25-hydroxyvitamin D levels, obesity and the metabolic syndrome among Korean children

2013 ◽  
Vol 23 (8) ◽  
pp. 785-791 ◽  
Author(s):  
S.H. Lee ◽  
S.M. Kim ◽  
H.S. Park ◽  
K.M. Choi ◽  
G.J. Cho ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Korean Children ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D

Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome

2019 ◽  
pp. 68-73
Author(s):  
Trong Nghia Nguyen ◽  
Thi Nhan Nguyen ◽  
Thi Dua Dao
Keyword(s):  
Metabolic Syndrome ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D ◽  
Key Words Metabolic Syndrome ◽  
And Control

Background: The metabolic syndrome is a constellation of cardiometabolic risk factors that tend to cluster together in affected individuals more often than predicted by chance. The presence of the metabolic syndrome substantially increases the risk of developing type 2 diabetes and cardiovascular disease, and is associated with a range of adverse clinical outcomes, many of which are closely associated with aging. Current estimates suggest that approximately 20 - 25% of the world’s population is affected by the metabolic syndrome. The prevalence of the metabolic syndrome rises with age and more than 45% of people aged over 60 years have the metabolic syndrome. Recent studies show that low vitamin D status is very common in the world and this is a risk factor of metabolic syndrome. Objective: (1) Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome. (2) Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Material and method: A cross-sectional study with control group on 318 adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 139 subjects with metabolic syndrome and control group of 179 healthy subjects. Metabolic syndrome was defined according to the IDF, NHLBI, AHA, WHF, IAS, IASO (2009). Plasma hydroxyvitamin D concentration was measured using chemiluminescent microparticle immunoassay. Reciever operating characteristic (ROC) curve were generated to assess sensitivity and specificity for different cut off value of 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Results: Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome was 26.4 ng/ml, incidence of plasma 25-hydroxyvitamin D deficiency (59.7%) was significantly higher than in control group (23.5%) (p < 0.001). The optimal cut off point for 25-OH-D concentration for predictor of metabolic syndrome as 26.4 ng/ml (AUC=0.657, sensitivity=53.4%, specificity=71.6%). Conclusion: In 139 subjects with metabolic syndrome, the plasma 25-hydroxyvitamin D concentration was 26.4 ng/ml and the incidence of 25-hydroxyvitamin D deficiency in the metabolic syndrome group was 59.7%. The optimal cut off point for plasma 25-hydroxyvitamin D concentration for predictor of metabolic syndrome as 26.4 ng/ml. Key words: Metabolic syndrome, 25-hydroxyvitamin D

scholarly journals Associations of Serum 25-Hydroxyvitamin D and Components of the Metabolic Syndrome in Obese Adolescent Females

Obesity ◽  
2011 ◽  
Vol 19 (11) ◽  
pp. 2214-2221 ◽  
Author(s):  
Ambika P. Ashraf ◽  
Jessica A. Alvarez ◽  
Barbara A. Gower ◽  
Karen H. Saenz ◽  
Kenneth L. McCormick
Keyword(s):  
Metabolic Syndrome ◽  
Adolescent Females ◽  
Obese Adolescent ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D

scholarly journals The associations of vitamin D status and dietary calcium with the metabolic syndrome: an analysis of the Victorian Health Monitor survey

2016 ◽  
Vol 20 (10) ◽  
pp. 1785-1796 ◽  
Author(s):  
Poonam K Pannu ◽  
Yun Zhao ◽  
Mario J Soares ◽  
Leonard S Piers ◽  
Zahid Ansari
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Sociodemographic Factors ◽  
Favourable Outcome ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D ◽  
Health Monitor

AbstractObjectiveTo examine the associations between serum 25-hydroxyvitamin D (25(OH)D), dietary Ca intake and presence of the metabolic syndrome (MetS).DesignA stratified cluster sample of a population aged 18–75 years from the Victorian Health Monitor survey.SettingNon-institutionalized adults living in private dwellings in Victoria, Australia.SubjectsAdults (n 3404) with complete data and without type 1 or type 2 diabetes.ResultsAdjusted for sociodemographic factors, physical characteristics and dietary covariates including Ca intake, every 10 nmol/l increase in serum 25(OH)D was significantly associated with decreased odds of MetS (adjusted odds ratio (AOR)=0·85, 95 % CI 0·80, 0·89; P<0·001). Relative to the low 25(OH)D tertile (median 33 nmol/l), there was a progressive decrease in odds of MetS that reached significance with the high 25(OH)D tertile (median 77 nmol/l; AOR=0·35, 95 % CI 0·26, 0·48; P<0·001). Every 500 mg/d increase in Ca intake adjusted for 25(OH)D did not reduce odds of MetS (AOR=0·81, 95 % CI 0·66, 1·06; P=0·141) but approached significance if unadjusted for 25(OH)D in the final model (AOR=0·81, 95 % CI 0·64, 1·02; P=0·073). No significant effect was obtained for tertiles of Ca intake. However, Ca and vitamin D tertile combinations suggested a beneficial effect of high Ca (median 1233 mg/d) only at low and medium 25(OH)D. The high 25(OH)D tertile was associated with significantly decreased odds of MetS regardless of Ca intake.ConclusionsA high vitamin D status significantly reduced the odds of MetS. A high Ca intake may have a similar favourable outcome but only at lower circulating concentrations of 25(OH)D.

Serum 25-hydroxyvitamin D levels and the metabolic syndrome in older persons: a population-based study

2011 ◽  
Vol 75 (5) ◽  
pp. 608-613 ◽  
Author(s):  
Mirjam M. Oosterwerff ◽  
Elisabeth M. W. Eekhoff ◽  
Martijn W. Heymans ◽  
Paul Lips ◽  
Natasja M. van Schoor
Keyword(s):  
Metabolic Syndrome ◽  
Older Persons ◽  
Population Based ◽  
Population Based Study ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D
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