Prognostic significance of serum uric acid in outpatients with chronic heart failure is complex and related to body mass index: Data from the IN-CHF Registry

2012 ◽  
Vol 22 (5) ◽  
pp. 442-448 ◽  
Author(s):  
S. Baldasseroni ◽  
R. Urso ◽  
A.P. Maggioni ◽  
F. Orso ◽  
G. Fabbri ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Uric Acid ◽  
Chronic Heart Failure ◽  
Serum Uric Acid ◽  
Body Mass ◽  
Prognostic Significance ◽  
Index Data ◽  
Body Mass Index Data

scholarly journals Should Prostate Specific Antigen be Adjusted for Body Mass Index? Data From the Baltimore Longitudinal Study of Aging

2009 ◽  
Vol 182 (6) ◽  
pp. 2646-2652 ◽  
Author(s):  
Stacy Loeb ◽  
H. Ballentine Carter ◽  
Edward M. Schaeffer ◽  
Luigi Ferrucci ◽  
Anna Kettermann ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Longitudinal Study ◽  
Prostate Specific Antigen ◽  
Body Mass ◽  
Specific Antigen ◽  
Index Data ◽  
Body Mass Index Data ◽  
Baltimore Longitudinal Study

scholarly journals Serum uric acid as a predictor of future hypertension: Stratified analysis based on body mass index and age

2016 ◽  
Vol 90 ◽  
pp. 201-206 ◽  
Author(s):  
Yuki Yokoi ◽  
Takahisa Kondo ◽  
Naoki Okumura ◽  
Keiko Shimokata ◽  
Shigeki Osugi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Body Mass ◽  
Stratified Analysis

Abstract 20287: Cardiac MIBG Imaging Predicts Cardiac Death in Patients With Chronic Heart Failure , Irrespective of Hyperuricemia

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Satoshi Takahashi ◽  
Takahisa Yamada ◽  
Takashi Morita ◽  
Yoshio Furukawa ◽  
Shunsuke Tamaki ◽  
...  
Keyword(s):  
Heart Failure ◽  
Uric Acid ◽  
Chronic Heart Failure ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Cardiac Death ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Washout Rate ◽  
Mibg Imaging

Background: Elevated uric acid level is associated with an increased risk of adverse outcome in patients with chronic heart failure (CHF). On the other hand, cardiac metaiodobenzylguanidine (MIBG) imaging provides prognostic information in patients with CHF. However, there is no information available on the prognostic value of cardiac MIBG imaging in CHF patients, relating to hyperuricemia. Methods: We enrolled 113 CHF outpatients (NYHA2.0±0.6, ischemic origin 48%) with radionuclide LVEF <40%(30±8%). The cardiac MIBG washout rate (WR) was calculated from the chest anterior view images obtained at 20 and 200 min after isotope injection. Abnormal WR was defined as >27% as reported previously. At the entry, we measured serum uric acid level and hyperuricemia was define as >7.0mg/dl. The primary end point was cardiac death. Reults: At the entry, 59 and 51 of 113 patients had abnormal WR and hyperuricemia, respectively. Serum uric acid level was significantly higher in patients with than without abnormal WR (7.3±1.8 vs 6.3±2.0 mg/dl, p=0.007). During the follow up period of 7.6±4.3 years, 35 patients had cardiac death. Cardiac death was significantly more often observed in patients with than without abnormal WR (47% vs 13%, p<0.001) and hyperuricemia (42% vs 23%, p=0.034). At multivariate Cox analysis, abnormal WR and hyperuricemia were significantly independently associated with cardiac death (p=0.02 and p=0.03, respectively). Patients with abnormal WR had a significantly greater risk of cardiac death than those with normal WR in group with hyperuricemia (p=0.004, harard ratio: 6.5, 95%CI 1.8 to 23.4) and without hyperuricemia(p=0.001, hazard ratio: 4.4, 95%CI 1.5 to 13.2). Conclusion: Cardiac MIBG imaging provides the additional information to hyperuricemia in CHF.

scholarly journals Nonlinear relationship between serum uric acid and body mass index: a cross-sectional study of a general population in coastal China

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Hui Zhou ◽  
Zhen Liu ◽  
Zhong Chao ◽  
Yeqing Chao ◽  
Lidan Ma ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
General Population ◽  
Serum Uric Acid ◽  
Body Mass ◽  
Large Scale ◽  
Cross Sectional ◽  
Men And Women ◽  
Nadir Point ◽  
Coastal China

Abstract Background Conflicting evidence exists on the relationship between body mass index (BMI) and serum uric acid (SUA). Therefore, we aimed to evaluate the SUA–BMI relationship in a large-scale epidemiological survey in coastal China. Methods This survey was conducted among the general population in the coastal region of China from September 2014 to January 2015. SUA Levels were measured by the automatic Sysmex Chemix-180 biochemical analyzer. Results A total of 6098 men (BMI: 24.58 ± 3.74 kg/m2) and 7941 women (24.56 ± 3.64 kg/m2) were included in this study. A stronger positive BMI-SUA association was found for men than women (all P-values < 0.05). The piecewise linear spline models indicated a U-shaped relationship of SUA-BMI association for both men and women; and the lowest turning points were at 19.12 kg/m2 for men and 21.3 kg/m2 for women. When BMIs were lower than the nadir point, each 1 kg/m2 increase in BMI related to a 7.74-fold (95% CI − 14.73, − 0.75) reduction for men and 2.70-fold reduction (− 4.47, − 0.94) for women in SUA levels. Once the BMI was higher than the nadir point, each 1 kg/m2 increase in BMI was related to a 5.10-fold (4.44, 5.77) increment for men and 3.93-fold increment (3.42, 4.43) for women in SUA levels. The regression coefficient differences between the two stages were 12.84 (5.66, 20.03) for men and 6.63 (4.65, 8.61) for women. Conclusions A U-shaped relationship between BMI and SUA was found for both men and women; the association was stronger for men than women.

scholarly journals Prognostic value of body mass index and waist circumference in patients with chronic heart failure (Spanish REDINSCOR Registry)

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P1536-P1536
Author(s):  
E. Roig ◽  
T. Puig ◽  
A. Ferrero Gregori ◽  
R. Vazquez ◽  
J. R. Gonzalez-Juanatey ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
Chronic Heart Failure ◽  
Waist Circumference ◽  
Body Mass ◽  
Prognostic Value
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