Cross-talk between the Ras GTPase and the Hog1 survival pathways in response to nitrosative stress in Paracoccidioides brasiliensis

Nitric Oxide ◽  
2019 ◽  
Vol 86 ◽  
pp. 1-11 ◽  
Author(s):  
Palloma Mendes Conceição ◽  
Alison Felipe Alencar Chaves ◽  
Marina Valente Navarro ◽  
Daniele Gonçalves Castilho ◽  
Juliana Cristina P. Calado ◽  
...  
Keyword(s):  
Cross Talk ◽  
Nitrosative Stress ◽  
Paracoccidioides Brasiliensis ◽  
Ras Gtpase ◽  
Survival Pathways

scholarly journals Organelle Cross-Talk in Apoptotic and Survival Pathways

2012 ◽  
Vol 2012 ◽  
pp. 1-2 ◽  
Author(s):  
Lina Ghibelli ◽  
Alina Grzanka
Keyword(s):  
Cross Talk ◽  
Survival Pathways

scholarly journals Cross-Talk between Mitochondrial Dysfunction-Provoked Oxidative Stress and Aberrant Noncoding RNA Expression in the Pathogenesis and Pathophysiology of SLE

2019 ◽  
Vol 20 (20) ◽  
pp. 5183 ◽  
Author(s):  
Chang-Youh Tsai ◽  
Song-Chou Hsieh ◽  
Cheng-Shiun Lu ◽  
Tsai-Hung Wu ◽  
Hsien-Tzung Liao ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dysfunction ◽  
Cross Talk ◽  
Noncoding Rna ◽  
Nitrosative Stress ◽  
Noncoding Rnas ◽  
The Body ◽  
Rna Expression ◽  
Epigenetic Regulations ◽  
The Cross

Systemic lupus erythematosus (SLE) is a prototype of systemic autoimmune disease involving almost every organ. Polygenic predisposition and complicated epigenetic regulations are the upstream factors to elicit its development. Mitochondrial dysfunction-provoked oxidative stress may also play a crucial role in it. Classical epigenetic regulations of gene expression may include DNA methylation/acetylation and histone modification. Recent investigations have revealed that intracellular and extracellular (exosomal) noncoding RNAs (ncRNAs), including microRNAs (miRs), and long noncoding RNAs (lncRNAs), are the key molecules for post-transcriptional regulation of messenger (m)RNA expression. Oxidative and nitrosative stresses originating from mitochondrial dysfunctions could become the pathological biosignatures for increased cell apoptosis/necrosis, nonhyperglycemic metabolic syndrome, multiple neoantigen formation, and immune dysregulation in patients with SLE. Recently, many authors noted that the cross-talk between oxidative stress and ncRNAs can trigger and perpetuate autoimmune reactions in patients with SLE. Intracellular interactions between miR and lncRNAs as well as extracellular exosomal ncRNA communication to and fro between remote cells/tissues via plasma or other body fluids also occur in the body. The urinary exosomal ncRNAs can now represent biosignatures for lupus nephritis. Herein, we’ll briefly review and discuss the cross-talk between excessive oxidative/nitrosative stress induced by mitochondrial dysfunction in tissues/cells and ncRNAs, as well as the prospect of antioxidant therapy in patients with SLE.

scholarly journals Effect of Nitrosative Stress on the S-Nitroso-Proteome of Paracoccidioides brasiliensis

2020 ◽  
Vol 11 ◽  
Author(s):  
Marina V. Navarro ◽  
Alison F. A. Chaves ◽  
Daniele G. Castilho ◽  
Isis Casula ◽  
Juliana C. P. Calado ◽  
...  
Keyword(s):  
Nitrosative Stress ◽  
Paracoccidioides Brasiliensis

scholarly journals A Structural Analysis of the PKCδVIII Variant Region and Cross Talk with Cell Survival Pathways

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Ann Anselme ◽  
Antonio Roki ◽  
Kevin Urbina ◽  
Brady Brooks ◽  
Iris Semer ◽  
...  
Keyword(s):  
Structural Analysis ◽  
Cell Survival ◽  
Cross Talk ◽  
Survival Pathways

Cross-talk between TNF-LIGHT and nitrosative stress in the airway remodeling of asthma

2016 ◽  
Author(s):  
Tsunahiko Hirano ◽  
Kosuke Ito ◽  
Nobutaka Edakuni ◽  
Kazuto Matsunaga
Keyword(s):  
Cross Talk ◽  
Nitrosative Stress ◽  
Airway Remodeling

Cross-talk between death and survival pathways

2003 ◽  
Vol 10 (8) ◽  
pp. 861-863 ◽  
Author(s):  
Shída Yousefi ◽  
Sébastían Conus ◽  
Hans-Uwe Símon
Keyword(s):  
Cross Talk ◽  
Survival Pathways

scholarly journals Cross-Talk Between Nitrosative Stress, Inflammation and Hypoxia-Inducible Factor in Patients with Adrenal Masses

2021 ◽  
Vol Volume 14 ◽  
pp. 6317-6330
Author(s):  
Barbara Choromańska ◽  
Piotr Myśliwiec ◽  
Tomasz Kozłowski ◽  
Magdalena Łuba ◽  
Piotr Wojskowicz ◽  
...  
Keyword(s):  
Cross Talk ◽  
Nitrosative Stress ◽  
Hypoxia Inducible Factor ◽  
Adrenal Masses
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