scholarly journals The temporal expression profile of a Nos3-related natural antisense RNA in the brain suggests a possible role in neurogenesis

Nitric Oxide ◽  
2017 ◽  
Vol 71 ◽  
pp. 27-31
Author(s):  
Gabriela G. Chavez ◽  
Gabriella Taylor ◽  
Jekaterina Garaliene ◽  
Guy P. Richardson ◽  
Sergei A. Korneev
Keyword(s):  
Expression Profile ◽  
Antisense Rna ◽  
Temporal Expression ◽  
Temporal Expression Profile ◽  
Natural Antisense Rna ◽  
The Brain

Temporal expression profile of CXC chemokines in serum of patients with spinal cord injury

2013 ◽  
Vol 63 (5) ◽  
pp. 363-367 ◽  
Author(s):  
Gholamhossein Hassanshahi ◽  
Masoud Amin ◽  
Anandakumar Shunmugavel ◽  
Reza Vazirinejad ◽  
Alireza Vakilian ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Expression Profile ◽  
Temporal Expression ◽  
Temporal Expression Profile ◽  
Cord Injury

scholarly journals Insertional mutagenesis in PLNR9C transgenic mouse: a case report and a review of the literature on cardiac-specific transgenic expression

2016 ◽  
Author(s):  
Alexander Kraev
Keyword(s):  
Expression Profile ◽  
Insertional Mutagenesis ◽  
Cardiac Development ◽  
Integration Site ◽  
Premature Death ◽  
Temporal Expression ◽  
Transgenic Expression ◽  
Temporal Expression Profile ◽  
Regulatory Circuit ◽  
Non Coding Rna

AbstractA mouse line with heterozygous transgenic expression of phospholamban carrying a substitution of cysteine for arginine 9 (PLNR9C) under the control of α-myosin heavy chain (αMHC) promoter features dilated cardiomyopathy, heart failure and premature death. In this line the transgenic array of 13 PLNR9C expression cassettes, arranged in a head-to-tail tandem orientation, has integrated into the homologous genomic site, the bi-directional promoter of the αMHC (Myh6) gene and the gene for the regulatory non-coding RNA Myheart (Mhrt), both of which are involved in the execution of the α/β MHC switch during cardiac development and pathology. PLNR9C overexpression is evident at the age of 1 month but declines dramatically along with a less pronounced concomitant decline of the resident PLN expression, until the animals die. Expression of the non-coding RNA Mhrt in PLNR9C mice also exhibits a profound deregulation, despite the presence of the second, intact allele. Hence the mouse strain does not faithfully model a human PLNR9C heterozygote, wherein both the mutant and the wildtype PLN alleles have, in all likelihood, the same temporal expression profile. The intricate regulatory circuit of the α/β MHC switch, involving the non-coding RNA Mhrt, was described in detail only recently, and since publications about αMHC-driven transgenes rarely contain the definition of the transgene integration site or temporal expression profile, it is suggested that some of the pathological phenomena attributed to expression of αMHC-driven transgenes may have an alternative explanation.

scholarly journals Spatio-temporal expression profile of matrix metalloproteinase (Mmp) modulators Reck and Sparc during the rat ovarian dynamics

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Gabriel Levin ◽  
Tatiane Maldonado Coelho ◽  
Nathali Guimarães Nóbrega ◽  
Marina Trombetta-Lima ◽  
Mari Cleide Sogayar ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Expression Profile ◽  
Temporal Expression ◽  
Temporal Expression Profile ◽  
Spatio Temporal ◽  
Ovarian Dynamics
Sign in / Sign up

Export Citation Format

Share Document