Structure guided chemical modifications of propylthiouracil reveal novel small molecule inhibitors of cytochrome B5 reductase 3

Nitric Oxide ◽  
2014 ◽  
Vol 42 ◽  
pp. 103-104
Author(s):  
Md. Mizanur Rahaman ◽  
David Koes ◽  
Courtney Sparacino-Watkins ◽  
Megan Miller ◽  
Carlos J. Camacho ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Cytochrome B5 ◽  
Chemical Modifications ◽  
Cytochrome B5 Reductase

Novel Small Molecule Inhibitors of Cytochrome B5 Reductase 3 Were Identified by Structure Guided Chemical Modifications of Propylthiouracil

2014 ◽  
Vol 76 ◽  
pp. S89-S90
Author(s):  
Md. Mizanur Rahaman ◽  
Fabio Reinders ◽  
Courtney Elaine Watkins ◽  
Anh Nguyen ◽  
Megan P. Miller ◽  
...  
Keyword(s):  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Cytochrome B5 ◽  
Chemical Modifications ◽  
Cytochrome B5 Reductase

scholarly journals Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochromeb5Reductase 3 That Increase Nitric Oxide Bioavailability

2015 ◽  
Vol 290 (27) ◽  
pp. 16861-16872 ◽  
Author(s):  
Md. Mizanur Rahaman ◽  
Fabio G. Reinders ◽  
David Koes ◽  
Anh T. Nguyen ◽  
Stephanie M. Mutchler ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Chemical Modifications ◽  
Nitric Oxide Bioavailability
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