P141. The cross-talk between myeloperoxidase and inducible nitric oxide synthase in epithelial ovarian cancer

Nitric Oxide ◽  
2006 ◽  
Vol 14 (4) ◽  
pp. 63-64
Author(s):  
Husam M. Abu-Soud ◽  
Ghassan M. Saed ◽  
Ruba Ali ◽  
Bob Morris ◽  
John Malone ◽  
...  
2014 ◽  
Vol 158 (1-2) ◽  
pp. 195-199 ◽  
Author(s):  
Agrimaldo Martins Filho ◽  
Millena Prata Jammal ◽  
Eliângela de Castro Côbo ◽  
Thales Parenti Silveira ◽  
Sheila Jorge Adad ◽  
...  

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Rosekeila Simões Nomelini ◽  
Lívia Carolina de Abreu Ribeiro ◽  
Beatriz Martins Tavares-Murta ◽  
Sheila Jorge Adad ◽  
Eddie Fernando Candido Murta

Tumor sections from nonneoplastic (n=15), benign (n=28), and malignant ovarian tumors (n=20) were obtained from 63 women. Immunohistochemistry of the tumor sections demonstrated that inducible nitric oxide synthase (iNOS) expression was increased in ovarian cancer samples compared to nonneoplastic or benign tumor samples. Using the Griess method, nitric oxide (NO) metabolite levels were also found to be elevated in malignant tumor samples compared to benign tumor samples (P<.05). For stage I ovarian cancer, intracystic NO levels>80 μMwere more frequent than NO levels<80 μM, and iNOS expression in well-differentiated carcinomas was greater than in moderately/poorly differentiated carcinomas (P<.05). These data suggest an important role for NO in ovarian carcinogenesis.


2016 ◽  
Vol 105 ◽  
pp. 183-185 ◽  
Author(s):  
Carlos Sanhueza ◽  
Joaquín Araos ◽  
Luciano Naranjo ◽  
Eric Barros ◽  
Lilian Toledo ◽  
...  

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