P090. Cross talk between endothelial nitric oxide synthase and arginase II

Nitric Oxide ◽  
2006 ◽  
Vol 14 (4) ◽  
pp. 46
Author(s):  
Gokce Topal ◽  
Annie Brunet ◽  
Laurence Walch ◽  
Jean-Luc Boucher ◽  
Monique David-Dufilho
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Cross Talk ◽  
Endothelial Nitric Oxide Synthase ◽  
Arginase Ii ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

scholarly journals A Model to Study the Inhibition of Arginase II with Noscapine & Its Derivatives

2020 ◽  
Vol 2 (2) ◽  
pp. 1-14
Author(s):  
Prashant Singh ◽  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Nitrate Tolerance ◽  
Arginase Ii ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Background and Purpose Nitrate tolerance can be explained based on the reduction of the vessel responsiveness and the same is used for endogenous vasodilator Nitric Oxide (NO). There are some limitations for the treatment of ischaemia, angina etc. and it attracted the scientists and researchers. The location of arginase II is endothelial cells in mitochondria and it is used to change the potency of endothelial nitric oxide synthase.

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

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