High-resolution and high-sensitivity SPECT imaging of breast phantoms

2004 ◽  
Vol 527 (1-2) ◽  
pp. 97-101 ◽  
Author(s):  
G.K Loudos ◽  
N.D Giokaris ◽  
K Mainta ◽  
N Sakelios ◽  
E Stiliaris ◽  
...  
Keyword(s):  
High Resolution ◽  
High Sensitivity ◽  
Spect Imaging ◽  
Breast Phantoms

scholarly journals SPEM: a state-of-the-art instrument for high resolution molecular imaging of small animal organs

2012 ◽  
Vol 10 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Marilia Alves dos Reis ◽  
Jorge Mejia ◽  
Ilza Rosa Batista ◽  
Marycel Rosa Felisa Figols de Barboza ◽  
Solange Amorim Nogueira ◽  
...  
Keyword(s):  
High Resolution ◽  
State Of The Art ◽  
Single Photon ◽  
Photon Emission ◽  
Small Animal ◽  
Software Tool ◽  
High Sensitivity ◽  
Spect Imaging ◽  
Innovative Technology ◽  
Animal Organs

OBJECTIVE: To describe the Single Photon Emission Microscope (SPEM), a state-of-the-art instrument for small animal SPECT imaging, and characterize its performance presenting typical images of different animal organs. METHODS: SPEM consists of two independent imaging devices based on high resolution scintillators, high sensitivity and resolution Electron-Multiplying CCDs and multi-pinhole collimators. During image acquisition, the mouse is placed in a rotational vertical holder between the imaging devices. Subsequently, an appropriate software tool based on the Maximum Likelihood algorithm iteratively produces the volumetric image. Radiopharmaceuticals for imaging kidneys, heart, thyroid and brain were used. The mice were injected with 74 to 148 MBq/0,3mL and scanned for 40 to 80 minutes, 30 to 60 minutes afterwards. During this procedure, the animals remained under ketamine/xilazine anesthesia. RESULTS: SPEM images of different mouse organs are presented, attesting the imaging capabilities of the instrument. CONCLUSION: SPEM is an innovative technology for small animal SPECT imaging providing high resolution images with appropriate sensitivity for pre-clinical research. Its use with appropriate radiotracers will allow translational investigation of several animal models of human diseases, their pharmacological treatment and the development of potential new therapeutic agents.

Backscattered Electron Imaging of GaAs/AlGaAs Super Lattice Structures with an Ultra-High- Resolution SEM

1988 ◽  
Vol 46 ◽  
pp. 204-205
Author(s):  
Kazumichi Ogura ◽  
Michael M. Kersker
Keyword(s):  
High Resolution ◽  
Layer Structure ◽  
High Sensitivity ◽  
Beam Current ◽  
Electron Beam Current ◽  
Lattice Structures ◽  
Super Lattice ◽  
Different Types ◽  
Backscattered Electron ◽  
Electron Imaging

Backscattered electron (BE) images of GaAs/AlGaAs super lattice structures were observed with an ultra high resolution (UHR) SEM JSM-890 with an ultra high sensitivity BE detector. Three different types of super lattice structures of GaAs/AlGaAs were examined. Each GaAs/AlGaAs wafer was cleaved by a razor after it was heated for approximately 1 minute and its crosssectional plane was observed.First, a multi-layer structure of GaAs (100nm)/AlGaAs (lOOnm) where A1 content was successively changed from 0.4 to 0.03 was observed. Figures 1 (a) and (b) are BE images taken at an accelerating voltage of 15kV with an electron beam current of 20pA. Figure 1 (c) is a sketch of this multi-layer structure corresponding to the BE images. The various layers are clearly observed. The differences in A1 content between A1 0.35 Ga 0.65 As, A1 0.4 Ga 0.6 As, and A1 0.31 Ga 0.69 As were clearly observed in the contrast of the BE image.

High Resolution and High Sensitivity Measurement of Methane at 1.51 μm

2006 ◽  
Vol 23 (9) ◽  
pp. 2415-2417
Author(s):  
Deng Lun-Hua ◽  
Gao Xiao-Ming ◽  
Cao Zhen-Song ◽  
Zhao Wei-Xiong ◽  
Zhang Wei-Jun
Keyword(s):  
High Resolution ◽  
High Sensitivity ◽  
Sensitivity Measurement
Sign in / Sign up

Export Citation Format

Share Document