Changes in the regional homogeneity of resting-state brain activity in minimal hepatic encephalopathy

2012 ◽  
Vol 507 (1) ◽  
pp. 5-9 ◽  
Author(s):  
Hua-Jun Chen ◽  
Xi-Qi Zhu ◽  
Ming Yang ◽  
Bin Liu ◽  
Yi Zhang ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Resting State ◽  
Brain Activity ◽  
Minimal Hepatic Encephalopathy ◽  
Regional Homogeneity

scholarly journals Altered Regional Homogeneity in the Development of Minimal Hepatic Encephalopathy: A Resting-State Functional MRI Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e42016 ◽  
Author(s):  
Ling Ni ◽  
Rongfeng Qi ◽  
Long Jiang Zhang ◽  
Jianhui Zhong ◽  
Gang Zheng ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Functional Mri ◽  
Resting State ◽  
Minimal Hepatic Encephalopathy ◽  
Regional Homogeneity ◽  
Mri Study

Abnormal regional homogeneity of resting-state brain activity in patients with HBV-related cirrhosis without overt hepatic encephalopathy

2013 ◽  
Vol 33 (3) ◽  
pp. 375-383 ◽  
Author(s):  
Xiao-Fei Lv ◽  
Ying-Wei Qiu ◽  
Jun-Zhang Tian ◽  
Chuan-Miao Xie ◽  
Lu-Jun Han ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Resting State ◽  
Brain Activity ◽  
Regional Homogeneity ◽  
Overt Hepatic Encephalopathy

Distinguishing hypochondriasis and schizophrenia using regional homogeneity: a resting-state fMRI study and support vector machine analysis

2021 ◽  
pp. 1-29
Author(s):  
Kangyu Jin ◽  
Zhe Shen ◽  
Guoxun Feng ◽  
Zhiyong Zhao ◽  
Jing Lu ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Resting State ◽  
Parietal Lobe ◽  
Brain Activity ◽  
Resting State Fmri ◽  
Brain Regions ◽  
Regional Homogeneity ◽  
Middle Temporal Gyrus ◽  
Support Vector ◽  
Fmri Study

Abstract Objective: A few former studies suggested there are partial overlaps in abnormal brain structure and cognitive function between Hypochondriasis (HS) and schizophrenia (SZ). But their differences in brain activity and cognitive function were unclear. Methods: 21 HS patients, 23 SZ patients, and 24 healthy controls (HC) underwent Resting-state functional magnetic resonance imaging (rs-fMRI) with the regional homogeneity analysis (ReHo), subsequently exploring the relationship between ReHo value and cognitive functions. The support vector machines (SVM) were used on effectiveness evaluation of ReHo for differentiating HS from SZ. Results: Compared with HC, HS showed significantly increased ReHo values in right middle temporal gyrus (MTG), left inferior parietal lobe (IPL) and right fusiform gyrus (FG), while SZ showed increased ReHo in left insula, decreased ReHo values in right paracentral lobule. Additionally, HS showed significantly higher ReHo values in FG, MTG and left paracentral lobule but lower in insula than SZ. The higher ReHo values in insula were associated with worse performance in MCCB in HS group. SVM analysis showed a combination of the ReHo values in insula and FG was able to satisfactorily distinguish the HS and SZ patients. Conclusion: our results suggested the altered default mode network (DMN), of which abnormal spontaneous neural activity occurs in multiple brain regions, might play a key role in the pathogenesis of HS, and the resting-state alterations of insula closely related to cognitive dysfunction in HS. Furthermore, the combination of the ReHo in FG and insula was a relatively ideal indicator to distinguish HS from SZ.

Abstract WMP117: Regional Homogeneity Changes In Patients With Transient Ischemic Attack: A Resting-state Functional Magnetic Resonance Imaging Study

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Jian Guo ◽  
Ning Chen ◽  
Muke Zhou ◽  
Pian Wang ◽  
Li He
Keyword(s):  
Transient Ischemic Attack ◽  
Neural Activity ◽  
Resting State ◽  
Right Hemisphere ◽  
Brain Activity ◽  
Imaging Study ◽  
Brain Regions ◽  
Regional Homogeneity ◽  
Anterior Cingulate ◽  
Ischemic Attack

Background: Transient ischemic attack (TIA) can increase the risk of some neurologic dysfunctions, of which the mechanism remains unclear. Resting-state functional MRI (rfMRI) is suggested to be a valuable tool to study the relation between spontaneous brain activity and behavioral performance. However, little is known about whether the local synchronization of spontaneous neural activity is altered in TIA patients. The purpose of this study is to detect differences in regional spontaneous activities throughout the whole brain between TIAs and normal controls. Methods: Twenty one TIA patients suffered an ischemic event in the right hemisphere and 21 healthy volunteers were enrolled in the study. All subjects were investigated using cognitive tests and rfMRI. The regional homogeneity (ReHo) was calculate and compared between two groups. Then a correlation analysis was performed to explore the relationship between ReHo values of brain regions showing abnormal resting-state properties and clinical variables in TIA group. Results: Compared with controls, TIA patients exhibited decreased ReHo in right dorsolateral prefrontal cortex (DLPFC), right inferior prefrontal gyrus, right ventral anterior cingulate cortex and right dorsal posterior cingular cortex. Moreover, the mean ReHo in right DLPFC and right inferior prefrontal gyrus were significantly correlated with MoCA in TIA patients. Conclusions: Neural activity in the resting state is changed in patients with TIA. The positive correlation between regional homogeneity of rfMRI and cognition suggests that ReHo may be a promising tool to better our understanding of the neurobiological consequences of TIA.

scholarly journals Evaluation of spontaneous regional brain activity in weight-recovered anorexia nervosa

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maria Seidel ◽  
Daniel Geisler ◽  
Viola Borchardt ◽  
Joseph A. King ◽  
Fabio Bernardoni ◽  
...  
Keyword(s):  
Resting State ◽  
Grey Matter ◽  
Brain Activity ◽  
Low Frequency ◽  
Regional Homogeneity ◽  
Degree Centrality ◽  
Mean Square ◽  
Regional Brain ◽  
Cortical Grey Matter ◽  
Regional Brain Activity

AbstractWhereas research using structural magnetic resonance imaging (sMRI) reports sizable grey matter reductions in patients suffering from acute anorexia nervosa (AN) to be largely reversible already after short-term weight gain, many task-based and resting-state functional connectivity (RSFC) studies suggest persistent brain alterations even after long-term weight rehabilitation. First investigations into spontaneous regional brain activity using voxel-wise resting-state measures found widespread abnormalities in acute AN, but no studies have compared intrinsic brain activity properties in weight-recovered individuals with a history of AN (recAN) with healthy controls (HCs). SMRI and RSFC data were analysed from a sample of 130 female volunteers: 65 recAN and 65 pairwise age-matched HC. Cortical grey matter thickness was assessed using FreeSurfer software. Fractional amplitude of low-frequency fluctuations (fALFFs), mean-square successive difference (MSSD), regional homogeneity (ReHo), voxel-mirrored homotopic connectivity (VHMC), and degree centrality (DC) were calculated. SMRI and RSFC data were analysed from a sample of 130 female volunteers: 65 recAN and 65 pairwise age-matched HCs. Cortical grey matter thickness was assessed using FreeSurfer software. Fractional amplitude of low-frequency fluctuations (fALFF), mean-square successive difference (MSSD), regional homogeneity (ReHo), voxel-mirrored homotopic connectivity (VHMC), and degree centrality (DC) were calculated. Abnormal regional homogeneity found in acute AN seems to normalize in recAN, supporting assumptions of a state rather than a trait marker. Aberrant fALFF values in the cerebellum and the infertior temporal gyrus could possibly hint towards trait factors or a scar (the latter, e.g., from prolonged periods of undernutrition), warranting further longitudinal research.

Alterations in regional homogeneity of resting-state brain activity in ketamine addicts

2012 ◽  
Vol 522 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Yanhui Liao ◽  
Jinsong Tang ◽  
Alex Fornito ◽  
Tieqiao Liu ◽  
Xiaogang Chen ◽  
...  
Keyword(s):  
Resting State ◽  
Brain Activity ◽  
Regional Homogeneity
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