scholarly journals Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease

2007 ◽  
Vol 26 (3) ◽  
pp. 590-596 ◽  
Author(s):  
Michael D. Boska ◽  
Khader M. Hasan ◽  
Danette Kibuule ◽  
Rebecca Banerjee ◽  
Erin McIntyre ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor Imaging ◽  
Murine Model ◽  
Diffusion Tensor ◽  
Neuronal Degeneration

Olfactory Function and Diffusion Tensor Imaging as Markers of Mild Cognitive Impairment in Early Stages of Parkinson's Disease

2021 ◽  
pp. 155005942110582
Author(s):  
Sophie A. Stewart ◽  
Laura Pimer ◽  
John D. Fisk ◽  
Benjamin Rusak ◽  
Ron A. Leslie ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Diffusion Tensor Imaging ◽  
Mild Cognitive Impairment ◽  
White Matter ◽  
Neurodegenerative Disorder ◽  
Diffusion Tensor ◽  
Early Stage ◽  
White Matter Integrity

Parkinson's disease (PD) is a neurodegenerative disorder that is typified by motor signs and symptoms but can also lead to significant cognitive impairment and dementia Parkinson's Disease Dementia (PDD). While dementia is considered a nonmotor feature of PD that typically occurs later, individuals with PD may experience mild cognitive impairment (PD-MCI) earlier in the disease course. Olfactory deficit (OD) is considered another nonmotor symptom of PD and often presents even before the motor signs and diagnosis of PD. We examined potential links among cognitive impairment, olfactory functioning, and white matter integrity of olfactory brain regions in persons with early-stage PD. Cognitive tests were used to established groups with PD-MCI and with normal cognition (PD-NC). Olfactory functioning was examined using the University of Pennsylvania Smell Identification Test (UPSIT) while the white matter integrity of the anterior olfactory structures (AOS) was examined using magnetic resonance imaging (MRI) diffusion tensor imaging (DTI) analysis. Those with PD-MCI demonstrated poorer olfactory functioning and abnormalities based on all DTI parameters in the AOS, relative to PD-NC individuals. OD and microstructural changes in the AOS of individuals with PD may serve as additional biological markers of PD-MCI.

scholarly journals Diffusion tensor imaging of Parkinson's disease, atypical parkinsonism, and essential tremor

2013 ◽  
Vol 28 (13) ◽  
pp. 1816-1822 ◽  
Author(s):  
Janey Prodoehl ◽  
Hong Li ◽  
Peggy J. Planetta ◽  
Christopher G. Goetz ◽  
Kathleen M. Shannon ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor Imaging ◽  
Essential Tremor ◽  
Diffusion Tensor ◽  
Atypical Parkinsonism

scholarly journals Is Diffusion Tensor Imaging a Good Biomarker for Early Parkinson's Disease?

2018 ◽  
Vol 9 ◽  
Author(s):  
Rachel P. Guimarães ◽  
Brunno M. Campos ◽  
Thiago J. de Rezende ◽  
Luiza Piovesana ◽  
Paula C. Azevedo ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Early Parkinson’S Disease

Poster #56 A DIFFUSION TENSOR IMAGING (DTI) STUDY OFWHITE MATTER INTEGRITY IN PARKINSON'S DISEASE (PD)

2012 ◽  
Vol 136 ◽  
pp. S300-S301
Author(s):  
Nailin Yao ◽  
Shirley Pang ◽  
Kevin Yu ◽  
Charlton Cheung ◽  
Richard Chang ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Diffusion Tensor Imaging Dti

Cerebellar Microstructural Abnormalities in Parkinson’s Disease: a Systematic Review of Diffusion Tensor Imaging Studies

2022 ◽  
Author(s):  
Maryam Haghshomar ◽  
Parnian Shobeiri ◽  
Seyed Arsalan Seyedi ◽  
Fatemeh Abbasi-Feijani ◽  
Amirhossein Poopak ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Imaging Studies
Sign in / Sign up

Export Citation Format

Share Document