Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis

2006 ◽  
Vol 24 (2) ◽  
pp. 213-225 ◽  
Author(s):  
Zarah Batulan ◽  
David M. Taylor ◽  
Rebecca J. Aarons ◽  
Sandra Minotti ◽  
Mohammad M. Doroudchi ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Primary Culture ◽  
Familial Amyotrophic Lateral Sclerosis ◽  
Culture Model ◽  
Shock Proteins ◽  
Lateral Sclerosis

Molecular chaperones as therapeutic targets in amyotrophic lateral sclerosis

2005 ◽  
Vol 33 (4) ◽  
pp. 551-552 ◽  
Author(s):  
B. Kalmar ◽  
D. Kieran ◽  
L. Greensmith
Keyword(s):  
Cell Death ◽  
Amyotrophic Lateral Sclerosis ◽  
Heat Shock ◽  
Molecular Chaperones ◽  
Apoptotic Cell ◽  
Structural Repair ◽  
Cell Death Pathway ◽  
Shock Proteins ◽  
Intracellular Aggregates ◽  
Lateral Sclerosis

Neurodegenerative diseases are characterized by a number of common hallmarks, such as the presence of intracellular aggregates and activation of the apoptotic cell-death pathway. Intracellular chaperones, responsible for protein integrity and structural repair, may play a crucial role in the progression of a disease. In this paper, we aim to summarize our understanding of the role and potential of a particular family of chaperones, the heat-shock proteins, in neurodegeneration, by focusing our discussion on models of motoneuron death.

Heat shock proteins in willow (Salix viminalis)

1990 ◽  
Vol 80 (2) ◽  
pp. 301-306
Author(s):  
Tiina Vahala ◽  
Tage Eriksson ◽  
Peter Engstrom
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Salix Viminalis ◽  
Shock Proteins
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