Self-fluorescent drug delivery vector based on genipin-crosslinked polyethylenimine conjugated globin nanoparticle

2017 ◽  
Vol 71 ◽  
pp. 17-24 ◽  
Author(s):  
Yan Zhang ◽  
Lina Mao ◽  
Juan Liu ◽  
Tianjun Liu
Keyword(s):  
Drug Delivery ◽  
Delivery Vector

Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

2020 ◽  
Vol 26 (15) ◽  
pp. 1637-1649 ◽  
Author(s):  
Imran Ali ◽  
Sofi D. Mukhtar ◽  
Heyam S. Ali ◽  
Marcus T. Scotti ◽  
Luciana Scotti
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Medical Science ◽  
Drug Carriers ◽  
Anticancer Drug Delivery ◽  
Ph Values ◽  
Delivery Vector ◽  
Future Challenges ◽  
Smart Drug ◽  
Smart Drug Delivery

Background: Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors that have recently been developed and recommended for use by scientists because of their potential targeting capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery. Method: The present review article provides an overview of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. Results: This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine, personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and perspectives, biodegradability and safety. Conclusions: This article will benefit academia, researchers, clinicians, and government authorities by providing a basis for further research advancements.

Advances in Oral Chitosan Based Nano Delivery System for colon Targeted Drug Delivery in Inflammatory Bowel Disease

2021 ◽  
pp. 3769-3774
Author(s):  
Ganesh Narayan Sharma ◽  
Ch. Praveen Kumar ◽  
Birendra Shrivastava ◽  
B. Kumar
Keyword(s):  
Drug Delivery ◽  
Oral Absorption ◽  
Drug Carriers ◽  
Multiple Features ◽  
Delivery Vector ◽  
Macromolecular Drugs ◽  
Natural Polysaccharide ◽  
Low Toxicity ◽  
Inflammatory Bowel ◽  
Derivatives Of

Nanomaterials can be used as drug carriers with multiple features, including target delivery triggered by environmental, pH, thermal responses, enhanced biocompatibility, and the ability to cross the blood-brain barrier. Chitosan (CS) is a natural polysaccharide largely obtained from marine crustaceans. It provides drug delivery vector for therapeutic CS and diagnostic CS, owing to its biocompatibility, biodegradability, low toxicity, and structural variability. Derivatives of CS such as quaternized CS, thiolated CS and carboxylated CS have enhanced its effectiveness in oral absorption of macromolecular drugs. This review discusses different forms of nanomaterials generated from CS and its derivatives for controlled drug delivery.

scholarly journals Structural and Hydrodynamic Analysis of a Novel Drug Delivery Vector: ELP[V5G3A2-150]

2013 ◽  
Vol 104 (9) ◽  
pp. 2009-2021 ◽  
Author(s):  
Daniel F. Lyons ◽  
Vu Le ◽  
Gene L. Bidwell ◽  
Wolfgang H. Kramer ◽  
Edwin A. Lewis ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hydrodynamic Analysis ◽  
Delivery Vector ◽  
Novel Drug

Preparation of folate-conjugated starch nanoparticles and its application to tumor-targeted drug delivery vector

2006 ◽  
Vol 51 (14) ◽  
pp. 1693-1697 ◽  
Author(s):  
Suyao Xiao ◽  
Chunyi Tong ◽  
Xuanming Liu ◽  
Danmi Yu ◽  
Qiaoling Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Delivery Vector ◽  
Starch Nanoparticles ◽  
Targeted Drug

scholarly journals Effect of Basic Cell-Penetrating Peptides on the Structural, Thermodynamic, and Hydrodynamic Properties of a Novel Drug Delivery Vector, ELP[V5G3A2-150]

Biochemistry ◽  
2014 ◽  
Vol 53 (6) ◽  
pp. 1081-1091 ◽  
Author(s):  
Daniel F. Lyons ◽  
Vu Le ◽  
Wolfgang H. Kramer ◽  
Gene L. Bidwell ◽  
Edwin A. Lewis ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Penetrating Peptides ◽  
Hydrodynamic Properties ◽  
Basic Cell ◽  
Delivery Vector ◽  
Cell Penetrating ◽  
Novel Drug

Hydrophobic myristic acid modified PAMAM dendrimers augment the delivery of tamoxifen to breast cancer cells

RSC Advances ◽  
2016 ◽  
Vol 6 (30) ◽  
pp. 24808-24819 ◽  
Author(s):  
Ishita Matai ◽  
P. Gopinath
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Cells ◽  
Myristic Acid ◽  
Breast Cancer Cells ◽  
Pamam Dendrimers ◽  
Hydrophobically Modified ◽  
Delivery Vector

In the present study, cationic generation 5 polyamido amine (G5 PAMAM) dendrimers were hydrophobically modified by grafting the surface with lipid-like myristic acid (My) tails to augment their potential as a drug delivery vector in vitro.

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