Genome-wide differential gene expression in children exposed to air pollution in the Czech Republic

2006 ◽  
Vol 600 (1-2) ◽  
pp. 12-22 ◽  
Author(s):  
D.M. van Leeuwen ◽  
M.H.M. van Herwijnen ◽  
M. Pedersen ◽  
L.E. Knudsen ◽  
M. Kirsch-Volders ◽  
...  
Keyword(s):  
Gene Expression ◽  
Air Pollution ◽  
Czech Republic ◽  
Differential Gene Expression ◽  
The Czech Republic ◽  
Genome Wide ◽  
Differential Gene

scholarly journals Genome-Wide Analysis of Differential Gene Expression and Splicing in Excitatory Neurons and Interneuron Subtypes

2019 ◽  
Vol 40 (5) ◽  
pp. 958-973 ◽  
Author(s):  
Melanie A. Huntley ◽  
Karpagam Srinivasan ◽  
Brad A. Friedman ◽  
Tzu-Ming Wang ◽  
Ada X. Yee ◽  
...  
Keyword(s):  
Gene Expression ◽  
Differential Gene Expression ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Excitatory Neurons ◽  
Differential Gene

scholarly journals Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0134865 ◽  
Author(s):  
Matthew N. Davies ◽  
Serena Verdi ◽  
Andrea Burri ◽  
Maciej Trzaskowski ◽  
Minyoung Lee ◽  
...  
Keyword(s):  
Gene Expression ◽  
Anxiety Disorder ◽  
Differential Gene Expression ◽  
Twin Study ◽  
Genetic Architecture ◽  
Genome Wide Association ◽  
Generalised Anxiety Disorder ◽  
Genome Wide ◽  
Differential Gene

Genome-Wide Differential Gene Expression Profiles in Broiler Chickens with Gangrenous Dermatitis

2012 ◽  
Vol 56 (4) ◽  
pp. 670-679 ◽  
Author(s):  
Duk Kyung Kim ◽  
Hyun S. Lillehoj ◽  
Kyung Woo Lee ◽  
Seung Ik Jang ◽  
Anthony P. Neumann ◽  
...  
Keyword(s):  
Gene Expression ◽  
Differential Gene Expression ◽  
Broiler Chickens ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Genome Wide ◽  
Differential Gene

Abstract T P240: Sex-specific Differential Gene Expression in a Murine Model of Experimental Intracerebral Hemorrhage

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Sankalp Gokhale ◽  
Dawn Kernagis ◽  
Beilei Lei ◽  
Yi-Ju Li ◽  
David Warner ◽  
...  
Keyword(s):  
Gene Expression ◽  
Intracerebral Hemorrhage ◽  
Differential Gene Expression ◽  
Mouse Genome ◽  
Differential Analysis ◽  
Genome Wide ◽  
Collagenase Injection ◽  
Differential Gene ◽  
Males And Females ◽  
Genome Wide Expression

Introduction: Decreased mortality and improved functional outcome in female compared to male mice after experimental intracerebral hemorrhage (ICH) has been demonstrated. We postulate that sex-specific differences in post-ICH gene expression may provide mechanistic insight. Methods: Ten to 12 week old C57/Bl6 male (M) and female in low estrus (LE-F) or high estrous state (HE-F) mice (n=3/group) underwent ICH induction via left intrastriatal collagenase injection. Whole brain samples were collected at baseline, immediately after sham injury and 6 hours after injury. Genome-wide expression profiling was performed with Affymetrix GeneChip Mouse Genome 2.0 to identify genes differentially expressed between baseline and 6 hours in males and females. Probes showing expression levels greater than log2 (10) for all samples were selected for differential analysis. Comparisons were made between baseline and 6-hour time points to determine significant differential gene expression in both sexes. An adjusted p < 0.05 was considered significant. Results: A total of 12136 probes qualified for our filtering criteria, representing 9830 genes. Of the genes tested, 119 in M, 76 in LE-F, and 420 in HE-F were expressed differently at 6 hours as compared to baseline. Of these genes, a total of 37 were shared in M and HE-F groups, 32 in M and LE-F groups, and 42 in HE-F and LE-F groups. Several pathways were identified based on the top list of genes in each group comparison, including coagulation and inflammatory mediator signaling. Conclusions: Sex-specific differential gene expression exists at 6 hours after experimental ICH. Further experiments will be designed to test whether these observed differences in gene expression are associated with outcome after experimental ICH and, thus, may yield novel therapeutic targets for translation into the human disease.

scholarly journals Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis

BMC Genomics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 825 ◽  
Author(s):  
Nuria Palau ◽  
Antonio Julià ◽  
Carlos Ferrándiz ◽  
Lluís Puig ◽  
Eduardo Fonseca ◽  
...  
Keyword(s):  
Gene Expression ◽  
T Cell ◽  
Differential Gene Expression ◽  
T Cell Activation ◽  
Cell Activation ◽  
Transcriptional Analysis ◽  
Genome Wide ◽  
Differential Gene
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