One pot synthesis of Curcumin-NSAIDs prodrug, spectroscopic characterization, conformational analysis, chemical reactivity, intramolecular interactions and first order hyperpolarizability by DFT method

2016 ◽  
Vol 1117 ◽  
pp. 173-180 ◽  
Author(s):  
Sangeeta Srivastava ◽  
Preeti Gupta ◽  
Arun Sethi ◽  
Ranvijay Pratap Singh
Keyword(s):  
Conformational Analysis ◽  
Chemical Reactivity ◽  
Dft Method ◽  
Spectroscopic Characterization ◽  
Intramolecular Interactions ◽  
One Pot ◽  
First Order ◽  
One Pot Synthesis

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

Synthesis, spectroscopic characterization, X-ray analysis and theoretical studies on the spectral features (FT-IR, 1H-NMR), chemical reactivity, NBO analyses of 2-(4-fluorophenyl)-2-(4-fluorophenylamino)acetonitrile and its docking into IDO enzyme

RSC Advances ◽  
2015 ◽  
Vol 5 (99) ◽  
pp. 80967-80977 ◽  
Author(s):  
Goutam Brahmachari ◽  
Abhishek Kumar ◽  
Ambrish Kumar Srivastava ◽  
Shashi Gangwar ◽  
Neeraj Misra ◽  
...  
Keyword(s):  
Green Synthesis ◽  
1H Nmr ◽  
Chemical Reactivity ◽  
Spectroscopic Characterization ◽  
Theoretical Studies ◽  
Spectral Features ◽  
One Pot ◽  
X Ray ◽  
Ft Ir

One-pot green synthesis and combined spectral and theoretical studies of 2-(4-fluorophenyl)-2-(4-fluorophenylamino)acetonitrile along with its X-ray crystallographic properties are described.

One-Pot Synthesis and Conformational Analysis of Six-Membered Cyclic Iodonium Salts

2020 ◽  
Vol 85 (14) ◽  
pp. 9161-9178
Author(s):  
Lucien D. Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris J. Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
One Pot ◽  
Iodonium Salts ◽  
One Pot Synthesis

scholarly journals One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

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