scholarly journals The Human Base Excision Repair Enzyme SMUG1 Directly Interacts with DKC1 and Contributes to RNA Quality Control

2013 ◽  
Vol 49 (2) ◽  
pp. 339-345 ◽  
Author(s):  
Laure Jobert ◽  
Hanne K. Skjeldam ◽  
Bjørn Dalhus ◽  
Anastasia Galashevskaya ◽  
Cathrine Broberg Vågbø ◽  
...  
Keyword(s):  
Quality Control ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Repair Enzyme ◽  
Rna Quality ◽  
Rna Quality Control ◽  
Base Excision

scholarly journals The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

2005 ◽  
Vol 389 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Ekaterina SMIRNOVA ◽  
Magali TOUEILLE ◽  
Enni MARKKANEN ◽  
Ulrich HÜBSCHER
Keyword(s):  
Quality Control ◽  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Ligase ◽  
Dna Polymerase Β ◽  
Flap Endonuclease 1 ◽  
Important Target ◽  
Dna Ligase I ◽  
Base Excision

The human checkpoint sensor and alternative clamp Rad9–Rad1–Hus1 can interact with and specifically stimulate DNA ligase I. The very recently described interactions of Rad9–Rad1–Hus1 with MutY DNA glycosylase, DNA polymerase β and Flap endonuclease 1 now complete our view that the long-patch base excision machinery is an important target of the Rad9–Rad1–Hus1 complex, thus enhancing the quality control of DNA.

scholarly journals Base excision repair enzyme endonuclease III suppresses mutagenesis caused by 8-hydroxy-dGTP

DNA Repair ◽  
2008 ◽  
Vol 7 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Tetsuya Suzuki ◽  
Kazuo Yamamoto ◽  
Hideyoshi Harashima ◽  
Hiroyuki Kamiya
Keyword(s):  
Base Excision Repair ◽  
Excision Repair ◽  
Repair Enzyme ◽  
Endonuclease Iii ◽  
Base Excision

Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe

2013 ◽  
Vol 49 (50) ◽  
pp. 5630 ◽  
Author(s):  
Ka-Ho Leung ◽  
Hong-Zhang He ◽  
Victor Pui-Yan Ma ◽  
Hai-Jing Zhong ◽  
Daniel Shiu-Hin Chan ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Repair Enzyme ◽  
G Quadruplex ◽  
Base Excision

A fluorescent G-quadruplex probe for the assay of base excision repair enzyme activity

2015 ◽  
Vol 51 (72) ◽  
pp. 13744-13747 ◽  
Author(s):  
Chang Yeol Lee ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Enzyme Activity ◽  
Base Excision Repair ◽  
Fluorescence Enhancement ◽  
Excision Repair ◽  
High Sensitivity ◽  
Repair Enzyme ◽  
Quadruplex Structure ◽  
G Quadruplex ◽  
Base Excision ◽  
Novel Strategy

A G-quadruplex probe incorporating 2-AP is utilized to develop a novel strategy to accurately determine UDG activity. The excision reaction promoted by UDG is designed to trigger the formation of G-quadruplex structure with significant fluorescence enhancement of 2-AP within the probe. By employing this strategy, UDG activity can be reliably determined with high sensitivity and specificity.

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