scholarly journals Neglected posterior urethral valve: Cause of irreversible renal damage and end-stage renal disease

2018 ◽  
Vol 74 (4) ◽  
pp. 410-411
Author(s):  
Suprita Kalra ◽  
Santosh Dey ◽  
Karunesh Chand ◽  
Madhuri Kanitkar
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Renal Damage ◽  
Posterior Urethral Valve ◽  
Urethral Valve ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Impact of surgical intervention on progression to end-stage renal disease in patients with posterior urethral valve

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Rishikesh Velhal ◽  
Aadhar Jain ◽  
Anveshi Nayan ◽  
Sujata Patwardhan ◽  
Bhushan Patil
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Posterior Urethral Valve ◽  
Renal Outcome ◽  
Lower Urinary Tract Obstruction ◽  
Significant Difference ◽  
Febrile Uti ◽  
Urethral Valve ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background Posterior urethral valve patients present with varied presentations at any age of life and have significant associated morbidity and require long-term follow-up and care. Methods This was a single-center ambispective cohort study carried out over a period of 2 years. Patient data regarding the symptoms, investigations, interventions, secondary complications were recorded and were followed up regularly during the study till either normalization of their creatinine level which was maintained up to one-year post-fulguration (non-CKD) or progression to end-stage renal disease (ESRD) requiring renal transplant. Various clinical factors were then compared between these groups. Results The age of presentation varies from 6 months antenatal period to a maximum of 34 years. Most common symptom was of lower urinary tract obstruction, followed by recurrent febrile UTI. The interval between disease presentation detection and PU valve fulguration ranged from 6 days to more than 5 years, median duration being 1 month. 85.7% patients had hydroureteronephrosis on initial USG. In VCUG, there was no significant difference found between the presence of reflux and poor renal outcome. Age of presentation greater than 2 years was seen in 52% of patients with CKD compared to only 10% patients in non-CKD group (significant, p value 0.02). Among patients who developed CKD, 60% of patients had PU valve fulguration after one month of disease presentation, while in contrast, among the non-CKD group, 80% of patients had it done within one month of disease presentation. (significant, p value 0.03). Conclusions Late age of presentation, delayed fulguration with high initial creatinine, and failure of serum creatinine to return to normal after one-month post-fulguration are important risk factors in the progression of the disease to ESRD. Symptomatic improvement after interventions does not correlate with progression to ESRD. The number of interventions also does not predict progression to ESRD. Interventions should be chosen wisely on case to restore near-normal physiology and delay progression to ESRD.

scholarly journals A case of Sotos syndrome presented with end-stage renal disease due to the posterior urethral valve

2014 ◽  
Vol 11 (2) ◽  
pp. 94
Author(s):  
Won Im Cho ◽  
Jung Min Ko ◽  
Hee Gyung Kang ◽  
Il-Soo Ha ◽  
Hae Il Cheong
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Posterior Urethral Valve ◽  
Sotos Syndrome ◽  
Urethral Valve ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals A case of Sotos syndrome presented with end-stage renal disease due to the posterior urethral valve

2014 ◽  
Vol 11 (2) ◽  
pp. 74-78
Author(s):  
Won Im Cho ◽  
Jung Min Ko ◽  
Hee Gyung Kang ◽  
Il-Soo Ha ◽  
Hae Il Cheong
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Posterior Urethral Valve ◽  
Sotos Syndrome ◽  
Urethral Valve ◽  
Stage Renal Disease ◽  
End Stage

Anterior urethral valve as a cause of end-stage renal disease

2001 ◽  
Vol 8 (3) ◽  
pp. 141-143 ◽  
Author(s):  
Cem Aygun ◽  
Oguz Guven ◽  
Mehmet I.lteris Tekin ◽  
Levent Peskircioglu ◽  
Hakan Ozkardes
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Anterior Urethral Valve ◽  
Urethral Valve ◽  
Stage Renal Disease ◽  
End Stage
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