55 Reactive oxygen species mediated regulation of mitochondrial biogenesis in the yeast Saccharomyces cerevisiae

Mitochondrion ◽  
2007 ◽  
Vol 7 (6) ◽  
pp. 420
Author(s):  
Cyrille Chevtzoff ◽  
Anne Galinier ◽  
Louis Casteilla ◽  
Bertrand Daignan-Fornier ◽  
Michel Rigoulet ◽  
...  
2009 ◽  
Vol 285 (3) ◽  
pp. 1733-1742 ◽  
Author(s):  
Cyrille Chevtzoff ◽  
Edgar D. Yoboue ◽  
Anne Galinier ◽  
Louis Casteilla ◽  
Bertrand Daignan-Fornier ◽  
...  

Mitochondrion ◽  
2010 ◽  
Vol 10 (2) ◽  
pp. 200
Author(s):  
Anne Devin ◽  
Michel Rigoulet ◽  
Bertrand Daignan-Fornier ◽  
Louis Casteilla ◽  
Anne Galinier ◽  
...  

2006 ◽  
Vol 53 (4) ◽  
pp. 679-684 ◽  
Author(s):  
Volodymyr I Lushchak

The budding yeast Saccharomyces cerevisiae is a well studied unicellular eukaryotic organism the genome of which has been sequenced. The use of yeast in many commercial systems makes its investigation important not only from basic, but also from practical point of view. Yeast may be grown under both aerobic and anaerobic conditions. The investigation of the response of eukaryotes to different kinds of stresses was pioneered owing to yeast and here we focus mainly on the so-called oxidative stress. It is a result of an imbalance between the formation and decomposition of reactive oxygen species increasing their steady-state concentration. Reactive oxygen species may attack any cellular component. In the present review oxidation of proteins in S. cerevisiae is analyzed. There are two connected approaches to study oxidative protein modification - characterization of the overall process and identification of individual oxidized proteins. Because all aerobic organisms possess special systems which defend them against reactive oxygen species, the involvement of so-called antioxidant enzymes, particularly superoxide dismutase and catalase, in the protection of proteins is also analyzed.


2017 ◽  
Vol 51 (7-8) ◽  
pp. 657-668 ◽  
Author(s):  
Leticia Selinger Galant ◽  
Marcos Martins Braga ◽  
Diego de Souza ◽  
Andreza Fabro de Bem ◽  
Luca Sancineto ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ritika Singh ◽  
Lucy Mohapatra ◽  
Alok Shiomurthi Tripathi

Abstract Background Diabetes mellitus is a lingering hyperglycemic ailment resulting in several life-threatening difficulties. Enduring hyperglycemia often persuades the buildup of reactive oxygen species that are the significant pathological makers of diabetic complications. The mitochondrial dysfunction, with mitochondrial damage and too much production of reactive oxygen species, have been proposed to be convoluted in the progress of insulin resistance. Numerous studies advocate that agents that enhance the mitochondrial number and/or decrease their dysfunction, could be greatly helpful in management of diabetes and its complications. Main body Mitochondrial biogenesis is an extremely delimited procedure arbitrated by numerous transcription influences, in which mitochondrial fusion and fission happen in synchronization in a standard vigorous cell. But this synchronization is greatly disturbed in diabetic condition designated by modification in the working of several important transcription factors regulating the expressions of different genes. Numerous preclinical and clinical investigations have suggested that, the compromised functions of mitochondria play a significant protagonist in development of pancreatic β-cell dysfunction, skeletal muscle insulin resistance and several diabetic complications. However, there are several phytoconstituents performing through numerous alleyways, either unswervingly by motivating biogenesis or indirectly by constraining or averting dysfunction and producing a beneficial effect on overall function of the mitochondria. Conclusion This review describes standard mitochondrial physiology and anomalous modifications that transpire in answer to persistent hyperglycemia in diabetes condition. It also discusses about the different phytoconstituents that can affect the biogenesis pathways of mitochondria and thus can be used in the treatment and prevention of diabetes.


RSC Advances ◽  
2015 ◽  
Vol 5 (94) ◽  
pp. 76718-76728 ◽  
Author(s):  
P. Suyana ◽  
S. Nishanth Kumar ◽  
Nimisha Madhavan ◽  
B. S. Dileep Kumar ◽  
Balagopal N. Nair ◽  
...  

Enhanced antifungal activity against the yeast species Candida albicans, Candida tropicalis and Saccharomyces cerevisiae was displayed by ZnS–ZnO nanocomposites prepared by a simple precipitation technique.


2017 ◽  
Vol 6 (1) ◽  
pp. 30-41 ◽  
Author(s):  
Selvaraj Rajakumar ◽  
Vasanthi Nachiappan

Cadmium (Cd) induces oxidative stress that generates reactive oxygen species (ROS) and increased lipid accumulation.


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