Complete genomic analysis of multidrug-resistance Pseudomonas aeruginosa Guangzhou-Pae617, the host of megaplasmid pBM413

2018 ◽  
Vol 117 ◽  
pp. 265-269 ◽  
Author(s):  
Junyan Liu ◽  
Lin Li ◽  
Brian M. Peters ◽  
Bing Li ◽  
Dingqiang Chen ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Multidrug Resistance ◽  
Genomic Analysis ◽  
Complete Genomic

scholarly journals Genomic analysis of carbapenem resistant Pseudomonas aeruginosa ST143 clone showing susceptibility to broad spectrum cephalosporins

2021 ◽  
Author(s):  
Ana Paula Streling ◽  
Rodrigo Cayô ◽  
Carolina S. Nodari ◽  
Luiz G.P. Almeida ◽  
Fernanda F. Santos ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Broad Spectrum ◽  
Genomic Analysis ◽  
Carbapenem Resistant

scholarly journals Genomic analysis of an extensively drug-resistant Pseudomonas aeruginosa ST312 harbouring IncU plasmid-mediated blaKPC-2 isolated from ascitic fluid

2021 ◽  
Vol 25 ◽  
pp. 151-153
Author(s):  
Daniela Cristina Tartari ◽  
Caetana Paes Zamparette ◽  
Graciele Martini ◽  
Sandra Christakis ◽  
Luiz Henrique Costa ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Ascitic Fluid ◽  
Genomic Analysis ◽  
Drug Resistant ◽  
Extensively Drug Resistant

Impact of Multidrug Resistance on Experimental Empyema by Pseudomonas aeruginosa

Respiration ◽  
2011 ◽  
Vol 82 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Evangelos J. Giamarellos-Bourboulis ◽  
Ira Tzepi ◽  
Irini Tsovolou ◽  
Aikaterini Spyridaki ◽  
Thomas Tsaganos ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Multidrug Resistance

scholarly journals Relationship between type III secretion toxins, biofilm formation, and antibiotic resistance in clinical Pseudomonas aeruginosa isolates

2021 ◽  
Vol 11 (6) ◽  
pp. 1075-1082
Author(s):  
S. Derakhshan ◽  
A. Rezaee ◽  
Sh. Mohammadi
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Multidrug Resistance ◽  
Type Iii Secretion ◽  
Biofilm Formation ◽  
Virulence Gene ◽  
Microtiter Plate ◽  
P Value ◽  
Type Iii ◽  
Disk Diffusion Assay

Background and aim. Pseudomonas aeruginosa is considered as a notorious pathogen due to its multidrug resistance and life threatening infections. We investigated the relationship between type III secretion toxins, biofilm formation, and antibiotic resistance among clinical P. aeruginosa isolates. Methods. A total of 70 genetically distinct clinical P. aeruginosa isolates were characterized for antibiotic resistance by disk diffusion assay. Biofilm formation was evaluated by microtiter plate method and presence of four exo genes (exoS, exoU, exoT and exoY) was investigated by PCR. A p-value < 0.05 was regarded statistically significant. Results. The most effective antibiotics were Meropenem and Piperacillin. Multidrug resistance was more prevalent in the ciprofloxacin-resistant isolates than in the susceptible isolates. The most frequently identified exo was exoS (37.1%). Genotype exoS/exoT was found in 4 isolates, while genotype exoU/exoT was not found. Prevalence of exoS was generally higher in the susceptible isolates than in the resistant isolates. A significant association was found between the formation of strong biofilm and resistance to antibiotics (p < 0.05). Prevalence of exoY and exoU was higher in the non-strong biofilm producers compared to the strong biofilm producers. Conclusion. Our study revealed formation of strong biofilm along with antibiotic resistance and the presence of exo genes in P. aeruginosa isolates. Knowledge of virulence gene profiles and biofilm formation may be useful in deciding appropriate treatment.

scholarly journals In Vitro Potency of CXA-101, a Novel Cephalosporin, against Pseudomonas aeruginosa Displaying Various Resistance Phenotypes, Including Multidrug Resistance

2009 ◽  
Vol 54 (1) ◽  
pp. 557-559 ◽  
Author(s):  
Catharine C. Bulik ◽  
Henry Christensen ◽  
David P. Nicolau
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Multidrug Resistance

ABSTRACT We describe the activity of a novel cephalosporin, CXA-101 (FR26 4205), against a panel of highly resistant Pseudomonas aeruginosa isolates collected from U.S. hospitals. CXA-101 demonstrated increased potency against this population of resistant isolates, with activity that is 4- to 10-fold higher than that of comparator agents in each phenotypic category. The addition of tazobactam did not improve its activity. CXA-101 appears to be a promising addition to the category of antipseudomonal β-lactams.

Complete genomic analysis of a Bangladeshi G1P[8] rotavirus strain detected in 2003 reveals a close evolutionary relationship with contemporary human Wa-like strains

2010 ◽  
Vol 10 (6) ◽  
pp. 746-754 ◽  
Author(s):  
Mustafizur Rahman ◽  
Jelle Matthijnssens ◽  
Farjana Saiada ◽  
Zahid Hassan ◽  
Elisabeth Heylen ◽  
...  
Keyword(s):  
Evolutionary Relationship ◽  
Genomic Analysis ◽  
Complete Genomic
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