Complete genome sequence and pathogenicity of fowl adenovirus serotype 4 involved in hydropericardium syndrome in Southwest China

2018 ◽  
Vol 117 ◽  
pp. 290-298 ◽  
Author(s):  
Ru Guan ◽  
Yiming Tian ◽  
Xiaoxiao Han ◽  
Xin Yang ◽  
Hongning Wang
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Southwest China ◽  
Adenovirus Serotype ◽  
Hydropericardium Syndrome ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

scholarly journals Complete genome sequence of a non-pathogenic strain of Fowl Adenovirus serotype 11: Minimal genomic differences between pathogenic and non-pathogenic viruses

Virology ◽  
2017 ◽  
Vol 501 ◽  
pp. 63-69 ◽  
Author(s):  
Angel E. Absalón ◽  
Andrés Morales-Garzón ◽  
Pedro F. Vera-Hernández ◽  
Diana V. Cortés-Espinosa ◽  
Sara M. Uribe-Ochoa ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Pathogenic Strain ◽  
Adenovirus Serotype ◽  
Fowl Adenovirus ◽  
Pathogenic Viruses

scholarly journals Pathogenicity and complete genome sequence of a fowl adenovirus serotype 8b isolate from China

2019 ◽  
Vol 98 (2) ◽  
pp. 573-580 ◽  
Author(s):  
Qinghua Huang ◽  
Xinxin Ma ◽  
Xiaoying Huang ◽  
Yanyan Huang ◽  
Shaohua Yang ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Adenovirus Serotype ◽  
Fowl Adenovirus

scholarly journals Complete Genome Sequence of a Fowl Adenovirus D Strain Isolated from Chickens with Inclusion Body Hepatitis in Japan

2021 ◽  
Vol 10 (46) ◽  
Author(s):  
Masaji Mase ◽  
Hiroshi Iseki ◽  
Satoko Watanabe
Keyword(s):  
Inclusion Body ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Common Origin ◽  
Fowl Adenovirus ◽  
Inclusion Body Hepatitis

We report the complete genome sequence of fowl adenovirus D (FAdV-D) strain JP/Tokushima/2010IBH, which was isolated from chickens with inclusion body hepatitis in Japan. This FAdV-D isolate was genetically highly similar to recent isolates from China, suggesting a common origin.

scholarly journals Identification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4

AMB Express ◽  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jingyi Liu ◽  
Nan Mei ◽  
Yaling Wang ◽  
Xinjin Shi ◽  
Hongjun Chen
Keyword(s):  
Amino Acid Sequence Analysis ◽  
Serum Samples ◽  
Protein Amino Acid ◽  
Adenovirus Serotype ◽  
Linear Peptide ◽  
Hydropericardium Syndrome ◽  
Hexon Protein ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

AbstractFowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated with viral species or serotypes. However, the epitopes of Hexon protein remain largely unknown. In this study, a monoclonal antibody (mAb) specific to Hexon protein of FAdV-4, designated as 3G8, was generated. Subsequently, the linear peptide recognized by 3G8 was mapped and identified as 213AYGAYVK219 using a series of overlapping peptides generated from Hexon protein. Amino acid sequence analysis revealed that the epitope recognized by 3G8 was highly conserved across all the FAdVs. The epitope was immunogenic and could be recognized by FAdV-4 positive chicken serum samples. These findings will enrich our knowledge regarding the epitope on Hexon and provide valuable information for further characterization of the antigenicity of Hexon protein.

scholarly journals Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors

Viruses ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 741 ◽  
Author(s):  
Zeng Wang ◽  
Jun Zhao
Keyword(s):  
Host Defense ◽  
Host Factors ◽  
Present Review ◽  
Defense System ◽  
Adenovirus Serotype ◽  
Vaccine Candidates ◽  
Hydropericardium Syndrome ◽  
Fowl Adenovirus ◽  
Host Defense System ◽  
Fowl Adenovirus Serotype 4

Since 2015, severe outbreaks of hepatitis-hydropericardium syndrome (HHS), caused by hypervirulent fowl adenovirus serotype 4 (FAdV-4), have emerged in several provinces in China, posing a great threat to poultry industry. So far, factors contributing to the pathogenesis of hypervirulent FAdV-4 have not been fully uncovered. Elucidation of the pathogenesis of FAdV-4 will facilitate the development of effective FAdV-4 vaccine candidates for the control of HHS and vaccine vector. The interaction between pathogen and host defense system determines the pathogenicity of the pathogen. Therefore, the present review highlights the knowledge of both viral and host factors contributing to the pathogenesis of hypervirulent FAdV-4 strains to facilitate the related further studies.

scholarly journals Genome Sequence of a Fowl Adenovirus Serotype 4 Strain Lethal to Chickens, Isolated from China

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Lintao Li ◽  
Ling Luo ◽  
Qingping Luo ◽  
Tengfei Zhang ◽  
Kang Zhao ◽  
...  
Keyword(s):  
Amino Acid ◽  
Sequence Analysis ◽  
Genome Sequence ◽  
Viral Genome ◽  
Open Reading Frame ◽  
Amino Acid Deletion ◽  
Adenovirus Serotype ◽  
Reading Frame ◽  
Fowl Adenovirus ◽  
Fowl Adenovirus Serotype 4

We report here the complete genome sequence of virulent fowl adenovirus serotype 4 strain HB1510, isolated from a diseased chicken with hydropericardium-hepatitis syndrome in Hubei, China, in 2015. The viral genome is 43,721 bp long, and sequence analysis showed an 11-amino-acid deletion in open reading frame 29 (ORF29).

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