Synthesis and in vitro evaluation of 2-(((2-ether)amino)methylene)-dimedone derivatives as potential antimicrobial agents

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Vol 114 ◽  
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Author(s):  
Ali Mohd Lone ◽  
Muzafar Ahmad Rather ◽  
Muneer Ahmad Bhat ◽  
Zubair Shanib Bhat ◽  
Irfan Qadir Tantry ◽  
...  
2020 ◽  
Vol 1220 ◽  
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Author(s):  
Vikrant Patil ◽  
Anurag Noonikara-Poyil ◽  
Shrinivas D. Joshi ◽  
Shivaputra A. Patil ◽  
Siddappa A. Patil ◽  
...  

2019 ◽  
Vol 97 (S263) ◽  
Author(s):  
Santa Viola ◽  
Giuseppe De Pasquale ◽  
Cristina Zappulla ◽  
Maria Cristina Curatolo ◽  
Maria Grazia Mazzone ◽  
...  

2015 ◽  
Vol 12 (7) ◽  
pp. 607-611 ◽  
Author(s):  
Ahmet Ozdemir ◽  
Mehlika Dilek Altıntop ◽  
Zerrin Canturk ◽  
Zafer Asim Kaplancikli

1996 ◽  
Vol 2 (4) ◽  
pp. 213-221 ◽  
Author(s):  
Kimiko Ubukata ◽  
Tomoko Muraki ◽  
Atsumi Igarashi ◽  
Yasuko Asahi ◽  
Masatoshi Konno

1998 ◽  
Vol 42 (4) ◽  
pp. 818-820 ◽  
Author(s):  
Philippe Brasseur ◽  
Sophie Lecoublet ◽  
Nathalie Kapel ◽  
Loic Favennec ◽  
Jean J. Ballet

ABSTRACT The susceptibilities of three bovine and two human Babesia divergens isolates to antimicrobial agents were evaluated in vitro by a tritiated hypoxanthine incorporation assay. The MICs at which 50% of isolates are inhibited (MIC50s) for mefloquine (chlorhydrate), chloroquine (sulfate), quinine (chlorhydrate), clindamycin (phosphate), pentamidine (isethionate), phenamidine (isethionate) plus oxomemazine (chlorhydrate), lincomycin (chlorhydrate monohydrate), and imidocarb (dipropionate) were determined. Except for imidocarb, the MIC50s observed for the different isolates were close. Imidocarb and the combination of phenamidine plus oxomemazine exhibited the highest in vitro activity, while antimalarial agents such as mefloquine, choroquine, and quinine were inactive. Other drugs had intermediate activities. The data support further in vitro evaluation of antimicrobial agents active against B. divergens for the improvement of therapeutic strategies.


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