Comparison of biofilm formation and antibiotic resistance pattern of Pseudomonas aeruginosa in human and environmental isolates

2017 ◽  
Vol 109 ◽  
pp. 94-98 ◽  
Author(s):  
Sayyad gholami ◽  
Mohammad Tabatabaei ◽  
Nasrollah Sohrabi
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Biofilm Formation ◽  
Resistance Pattern ◽  
Environmental Isolates ◽  
Antibiotic Resistance Pattern

The correlation between biofilm formation capability and antibiotic resistance pattern in Pseudomonas aeruginosa

Gene Reports ◽  
2020 ◽  
Vol 18 ◽  
pp. 100561 ◽  
Author(s):  
Pezhman Karami ◽  
Azad Khaledi ◽  
Rasool Yousefi Mashoof ◽  
Mojtaba Hedayat Yaghoobi ◽  
Manoochehr Karami ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Biofilm Formation ◽  
Resistance Pattern ◽  
Antibiotic Resistance Pattern

scholarly journals Correlation of biofilm production with antibiotic susceptibility pattern of Pseudomonas aeruginosa from various clinical specimens

2022 ◽  
Vol 13 (1) ◽  
pp. 88-92
Author(s):  
M Swapna ◽  
G Sumathi ◽  
M Anitha
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Biofilm Formation ◽  
Antibiotic Sensitivity ◽  
Microtiter Plate ◽  
Resistance Pattern ◽  
Sensitivity Testing ◽  
Clinical Specimens ◽  
Biofilm Production ◽  
Microbiological Methods

Background: Pseudomonas aeruginosa is one of the most prevalent nosocomial pathogens that cause a life-threatening infection. One of the important characteristics of P. aeruginosa is biofilm formation which leads to antibiotic resistance. Aims and Objectives: The aim of the study was to study the antibiotic resistance pattern of P. aeruginosa isolates and correlation with their biofilm-production. Materials and Methods: A total of 87 P. aeruginosa isolates from different clinical specimens were processed and confirmed by conventional microbiological methods as per standard methodology. Antibiotic sensitivity testing was done for all isolates. Biofilm producing isolates were identified by the microtiter plate method (MTPM). Results: Of 87 P. aeruginosa isolates, majority were from pus 33 (38%), followed by urine 26 (30%), sputum 19 (22%), body fluids 7 (8%), and blood 2 (2%). Biofilm producing isolates showed more resistance in comparison to non-biofilm producers. The observed difference between biofilm formation for multidrug resistant and susceptible isolates was found to be statistically significant. Conclusion: MTPM method was an effective test for detection of biofilm formation and was also able to verify biofilm production by P. aeruginosa. This indicated a higher propensity among the clinical isolates of P. aeruginosa to form biofilm and revealed a positive correlation between biofilm formation and antibiotic resistance. This indicates the need for testing of even susceptible isolates for virulence factors such as biofilm production.

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