Biological therapeutics of Pongamia pinnata coated zinc oxide nanoparticles against clinically important pathogenic bacteria, fungi and MCF-7 breast cancer cells

2017 ◽  
Vol 104 ◽  
pp. 268-277 ◽  
Author(s):  
Balasubramanian Malaikozhundan ◽  
Baskaralingam Vaseeharan ◽  
Sekar Vijayakumar ◽  
Karuppiah Pandiselvi ◽  
Mohamed Ali Rajamohamed Kalanjiam ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Zinc Oxide ◽  
Cancer Cells ◽  
Zinc Oxide Nanoparticles ◽  
Breast Cancer Cells ◽  
Pathogenic Bacteria ◽  
Pongamia Pinnata ◽  
Oxide Nanoparticles ◽  
Biological Therapeutics ◽  
Mcf 7

scholarly journals Biological Fabrication and Characterization of Zinc Oxide Nanoparticles Using Gymnema Sylvestre Potentially Produces Toxicity in Breast Cancer Cells -MCF-7

2021 ◽  
Author(s):  
Murali Santhoshkumar ◽  
Agilan Balupillai ◽  
Ernest David
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Zinc Oxide Nanoparticles ◽  
Breast Cancer Cells ◽  
Oxide Nanoparticles ◽  
Gymnema Sylvestre ◽  
Zno Nps ◽  
Fabrication And Characterization ◽  
Mcf 7

Abstract To study the biological fabrication and characterization of zinc oxide nanoparticles (ZnO NPs) using Gymnema sylvestre and their toxicity to breast cancer cells MCF-7.In the existing work, ZnO NPs were synthesized using leaf extract of the Indian medicinal plant Gymnema sylvestre and it was characterized by Particle size, Zeta potential, FT-IR, XRD and SEM analyses.This ZnO NPs to have potentially validated anticancer role in breast cancer cells MCF-7 in vitro approach.The plant-based synthesized ZnO NPs were evaluated against the inhibitory role on breast cancer cell lines. We significantly observed that ZnO-NPs induce efficient toxicity of MCF-7 cells by increasing ROS, mitochondrion membrane damage and apoptotic morphological alterations. These results stated that ZnO-NP induces Bax and Caspases and down-regulates Bcl-2 proteins in MCF-7 cells. Thus, the biologically synthesized ZnO NPs were identified as good performance to inhibit breast cancer cell growth even at low concentrations.

scholarly journals Zinc Oxide Nanoparticles Induces Apoptosis in Human Breast Cancer Cells via Caspase-8 and P53 Pathway

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Haitham Ali Kadhem ◽  
Sumayah Abdulhussien Ibraheem ◽  
Majid Sakhi Jabir ◽  
Afraa Ali Kadhim ◽  
Zainab Jihad Taqi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Zinc Oxide ◽  
Cancer Cells ◽  
Zinc Oxide Nanoparticles ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Caspase 8 ◽  
Oxide Nanoparticles ◽  
Human Breast Cancer Cells ◽  
Human Breast

Frizzled-7-targeted delivery of zinc oxide nanoparticles to drug-resistant breast cancer cells

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12858-12870 ◽  
Author(s):  
Pakatip Ruenraroengsak ◽  
Darya Kiryushko ◽  
Ioannis G. Theodorou ◽  
Michał M. Klosowski ◽  
Erik R. Taylor ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Resistance ◽  
Zinc Oxide ◽  
Targeted Delivery ◽  
Zinc Oxide Nanoparticles ◽  
Breast Cancer Cells ◽  
Oxide Nanoparticles ◽  
Drug Resistant ◽  
Cancer Subtypes ◽  
Aggressive Breast Cancer

There is a need for novel strategies to treat aggressive breast cancer subtypes and overcome drug resistance.

scholarly journals Estimation of radiation dose-reduction factor for cerium oxide nanoparticles in MRC-5 human lung fibroblastic cells and MCF-7 breast-cancer cells

2018 ◽  
Vol 46 (sup3) ◽  
pp. S1215-S1225 ◽  
Author(s):  
Nouraddin Abdi Goushbolagh ◽  
Razzagh Abedi Firouzjah ◽  
Kourosh Ebrahimnejad Gorji ◽  
Mohammadjavad Khosravanipour ◽  
Saman Moradi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Dose ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Human Lung ◽  
Reduction Factor ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Fibroblastic Cells ◽  
Mcf 7

scholarly journals Effect of topotycan and zinc oxide nanoparticles combination on cytotoxicity and P53 gene expression against breast cancer (MCF-7) cell line

2020 ◽  
Vol 22 (1) ◽  
pp. 192-197
Author(s):  
Alireza Sharifian ◽  
Fahimeh Baghbani-Arani ◽  
Hasan Sahebjami ◽  
◽  
◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Zinc Oxide ◽  
Cell Line ◽  
Zinc Oxide Nanoparticles ◽  
P53 Gene ◽  
Oxide Nanoparticles ◽  
Mcf 7
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